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Journal Abstract Search


167 related items for PubMed ID: 17921191

  • 1. Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier.
    Lockman PR, Manda VK, Geldenhuys WJ, Mittapalli RK, Thomas F, Albayati ZF, Crooks PA, Dwoskin LP, Allen DD.
    J Pharmacol Exp Ther; 2008 Jan; 324(1):244-50. PubMed ID: 17921191
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  • 3. N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.
    Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT.
    J Pharmacol Exp Ther; 2008 Aug; 326(2):563-76. PubMed ID: 18460644
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  • 4. The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens.
    Rahman S, Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT.
    Neuropharmacology; 2007 Mar; 52(3):755-63. PubMed ID: 17097117
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  • 5. Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo.
    Rahman S, Zhang Z, Papke RL, Crooks PA, Dwoskin LP, Bardo MT.
    Br J Pharmacol; 2008 Feb; 153(4):792-804. PubMed ID: 18059317
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  • 8. 3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter.
    Geldenhuys WJ, Lockman PR, Nguyen TH, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD.
    Bioorg Med Chem; 2005 Jul 01; 13(13):4253-61. PubMed ID: 15878282
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  • 9. The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.
    Smith AM, Dhawan GK, Zhang Z, Siripurapu KB, Crooks PA, Dwoskin LP.
    Biochem Pharmacol; 2009 Oct 01; 78(7):889-97. PubMed ID: 19631612
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  • 13. Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.
    Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP.
    Bioorg Med Chem Lett; 2004 Apr 19; 14(8):1869-74. PubMed ID: 15050618
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  • 15. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices.
    Wilkins LH, Haubner A, Ayers JT, Crooks PA, Dwoskin LP.
    J Pharmacol Exp Ther; 2002 Jun 19; 301(3):1088-96. PubMed ID: 12023541
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  • 18. Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.
    Neugebauer NM, Zhang Z, Crooks PA, Dwoskin LP, Bardo MT.
    Psychopharmacology (Berl); 2006 Mar 19; 184(3-4):426-34. PubMed ID: 16220336
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  • 19. In vivo and in vitro evidence for nonrestricted transport of 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein tetraacetoxymethyl ester at the blood-brain barrier.
    Hirohashi T, Terasaki T, Shigetoshi M, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Feb 19; 280(2):813-9. PubMed ID: 9023295
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