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289 related items for PubMed ID: 17932951

  • 1. Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation.
    Pääjärvi G, Jernström B, Seidel A, Stenius U.
    Mol Carcinog; 2008 Apr; 47(4):301-9. PubMed ID: 17932951
    [Abstract] [Full Text] [Related]

  • 2. Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.
    Dreij K, Seidel A, Jernström B.
    Chem Res Toxicol; 2005 Apr; 18(4):655-64. PubMed ID: 15833025
    [Abstract] [Full Text] [Related]

  • 3. H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides.
    Mattsson A, Jernström B, Cotgreave IA, Bajak E.
    Chem Biol Interact; 2009 Jan 15; 177(1):40-7. PubMed ID: 18848825
    [Abstract] [Full Text] [Related]

  • 4. Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide.
    Lagerqvist A, Håkansson D, Prochazka G, Lundin C, Dreij K, Segerbäck D, Jernström B, Törnqvist M, Seidel A, Erixon K, Jenssen D.
    DNA Repair (Amst); 2008 Aug 02; 7(8):1202-12. PubMed ID: 18479980
    [Abstract] [Full Text] [Related]

  • 5. Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene.
    Malmlöf M, Pääjärvi G, Högberg J, Stenius U.
    Toxicol Sci; 2008 Apr 02; 102(2):232-40. PubMed ID: 18096571
    [Abstract] [Full Text] [Related]

  • 6. Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases.
    Sundberg K, Dreij K, Seidel A, Jernström B.
    Chem Res Toxicol; 2002 Feb 02; 15(2):170-9. PubMed ID: 11849043
    [Abstract] [Full Text] [Related]

  • 7. Catalytic activities of human alpha class glutathione transferases toward carcinogenic dibenzo[a,l]pyrene diol epoxides.
    Dreij K, Sundberg K, Johansson AS, Nordling E, Seidel A, Persson B, Mannervik B, Jernström B.
    Chem Res Toxicol; 2002 Jun 02; 15(6):825-31. PubMed ID: 12067250
    [Abstract] [Full Text] [Related]

  • 8. Formation and differential repair of covalent DNA adducts generated by treatment of human cells with (+/-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxide.
    Spencer WA, Singh J, Orren DK.
    Chem Res Toxicol; 2009 Jan 02; 22(1):81-9. PubMed ID: 19053321
    [Abstract] [Full Text] [Related]

  • 9. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA, Zhu Q, El-Mahdy M, Venkatachalam S, Wani AA.
    Cancer Res; 2000 Apr 15; 60(8):2273-80. PubMed ID: 10786695
    [Abstract] [Full Text] [Related]

  • 10. DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells.
    Lagerqvist A, Håkansson D, Lundin C, Prochazka G, Dreij K, Segerbäck D, Jernström B, Törnqvist M, Frank H, Seidel A, Erixon K, Jenssen D.
    DNA Repair (Amst); 2011 Aug 15; 10(8):877-86. PubMed ID: 21727035
    [Abstract] [Full Text] [Related]

  • 11. Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a,l]pyrene (dibenzo[def,p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene.
    Amin S, Desai D, Dai W, Harvey RG, Hecht SS.
    Carcinogenesis; 1995 Nov 15; 16(11):2813-7. PubMed ID: 7586203
    [Abstract] [Full Text] [Related]

  • 12. Nickel (II) enhances benzo[a]pyrene diol epoxide-induced mutagenesis through inhibition of nucleotide excision repair in human cells: a possible mechanism for nickel (II)-induced carcinogenesis.
    Hu W, Feng Z, Tang MS.
    Carcinogenesis; 2004 Mar 15; 25(3):455-62. PubMed ID: 14604891
    [Abstract] [Full Text] [Related]

  • 13. Differential c-myc expression profiles in normal human bronchial epithelial cells following treatment with benzo[a]pyrene, benzo[a]pyrene-4,5 epoxide, and benzo[a]pyrene-7,8-9,10 diol epoxide.
    Fields WR, Desiderio JG, Leonard RM, Burger EE, Brown BG, Doolittle DJ.
    Mol Carcinog; 2004 Jun 15; 40(2):79-89. PubMed ID: 15170813
    [Abstract] [Full Text] [Related]

  • 14. PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells.
    Burdick AD, Ivnitski-Steele ID, Lauer FT, Burchiel SW.
    Carcinogenesis; 2006 Nov 15; 27(11):2331-40. PubMed ID: 16774943
    [Abstract] [Full Text] [Related]

  • 15. Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase.
    Mukherjee JJ, Sikka HC.
    Carcinogenesis; 2006 Mar 15; 27(3):631-8. PubMed ID: 16244358
    [Abstract] [Full Text] [Related]

  • 16. Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
    Donauer J, Schreck I, Liebel U, Weiss C.
    Arch Toxicol; 2012 Feb 15; 86(2):329-37. PubMed ID: 21983885
    [Abstract] [Full Text] [Related]

  • 17. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC, Tsou TC.
    Toxicol In Vitro; 2009 Aug 15; 23(5):897-905. PubMed ID: 19470404
    [Abstract] [Full Text] [Related]

  • 18. DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53.
    Mukherjee JJ, Kumar S.
    Mutat Res; 2013 Jul 04; 755(1):61-7. PubMed ID: 23692869
    [Abstract] [Full Text] [Related]

  • 19. Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Huang MT, Wood AW, Chang RL, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Cancer Res; 1986 Feb 04; 46(2):558-66. PubMed ID: 3079665
    [Abstract] [Full Text] [Related]

  • 20. Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations.
    Khan MKA, Akhtar S, Arif JM.
    Interdiscip Sci; 2018 Dec 04; 10(4):653-673. PubMed ID: 28374118
    [Abstract] [Full Text] [Related]

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