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Journal Abstract Search


347 related items for PubMed ID: 17933411

  • 1. Saturation mutagenesis reveals the importance of residues alphaR145 and alphaF146 of penicillin acylase in the synthesis of beta-lactam antibiotics.
    Jager SA, Shapovalova IV, Jekel PA, Alkema WB, Svedas VK, Janssen DB.
    J Biotechnol; 2008 Jan 01; 133(1):18-26. PubMed ID: 17933411
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  • 7. Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation.
    Youshko MI, Moody HM, Bukhanov AL, Boosten WH, Svedas VK.
    Biotechnol Bioeng; 2004 Feb 05; 85(3):323-9. PubMed ID: 14748088
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  • 8. Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.
    Otten LG, Sio CF, van der Sloot AM, Cool RH, Quax WJ.
    Chembiochem; 2004 Jun 07; 5(6):820-5. PubMed ID: 15174165
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  • 9. Efficient enzymatic synthesis of ampicillin by mutant Alcaligenes faecalis penicillin G acylase.
    Deng S, Su E, Ma X, Yang S, Wei D.
    J Biotechnol; 2015 Apr 10; 199():62-8. PubMed ID: 25681630
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  • 14. Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues.
    Oh B, Kim K, Park J, Yoon J, Han D, Kim Y.
    Biochem Biophys Res Commun; 2004 Jun 25; 319(2):486-92. PubMed ID: 15178432
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  • 15. The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase.
    Alkema WB, Dijkhuis AJ, De Vries E, Janssen DB.
    Eur J Biochem; 2002 Apr 25; 269(8):2093-100. PubMed ID: 11985586
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  • 16. Improved activity and pH stability of E. coli ATCC 11105 penicillin acylase by error-prone PCR.
    Balci H, Ozturk MT, Pijning T, Ozturk SI, Gumusel F.
    Appl Microbiol Biotechnol; 2014 May 25; 98(10):4467-77. PubMed ID: 24389703
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  • 17. Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase.
    Alkema WB, Hensgens CM, Snijder HJ, Keizer E, Dijkstra BW, Janssen DB.
    Protein Eng Des Sel; 2004 May 25; 17(5):473-80. PubMed ID: 15254299
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  • 18. Efficient synthesis of β-lactam antibiotics with in situ product removal by a newly isolated penicillin G acylase.
    Pan X, Li A, Peng Z, Ji X, Chu J, He B.
    Bioorg Chem; 2020 Jun 25; 99():103765. PubMed ID: 32213361
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  • 19. Efficient synthesis of β-lactam antibiotics with very low product hydrolysis by a mutant Providencia rettgeri penicillin G acylase.
    Pan X, Wang L, Ye J, Qin S, He B.
    Appl Microbiol Biotechnol; 2018 Feb 25; 102(4):1749-1758. PubMed ID: 29306966
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