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528 related items for PubMed ID: 1793460

  • 1. Amyloid plaques, neurofibrillary tangles and neuronal loss in brains of transgenic mice overexpressing a C-terminal fragment of human amyloid precursor protein.
    Kawabata S, Higgins GA, Gordon JW.
    Nature; 1991 Dec 12; 354(6353):476-8. PubMed ID: 1793460
    [Abstract] [Full Text] [Related]

  • 2. Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice.
    Hartmann J, Erb C, Ebert U, Baumann KH, Popp A, König G, Klein J.
    Neuroscience; 2004 Dec 12; 125(4):1009-17. PubMed ID: 15120860
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  • 3. Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
    Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M, Nakahara J, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K.
    Eur J Neurosci; 2004 May 12; 19(10):2826-38. PubMed ID: 15147316
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  • 4. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.
    Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F.
    Nature; 1995 Feb 09; 373(6514):523-7. PubMed ID: 7845465
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  • 5. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep 09; 23(3):653-62. PubMed ID: 16829076
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  • 6. Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.
    Ribé EM, Pérez M, Puig B, Gich I, Lim F, Cuadrado M, Sesma T, Catena S, Sánchez B, Nieto M, Gómez-Ramos P, Morán MA, Cabodevilla F, Samaranch L, Ortiz L, Pérez A, Ferrer I, Avila J, Gómez-Isla T.
    Neurobiol Dis; 2005 Dec 09; 20(3):814-22. PubMed ID: 16125396
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  • 7. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.
    Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E.
    Science; 2001 Aug 24; 293(5534):1487-91. PubMed ID: 11520987
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  • 8. Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation.
    Koistinaho M, Kettunen MI, Goldsteins G, Keinänen R, Salminen A, Ort M, Bures J, Liu D, Kauppinen RA, Higgins LS, Koistinaho J.
    Proc Natl Acad Sci U S A; 2002 Feb 05; 99(3):1610-5. PubMed ID: 11818564
    [Abstract] [Full Text] [Related]

  • 9. Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites.
    Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, Matsubara E, Abe K, Nakazato Y.
    Virchows Arch; 2002 Oct 05; 441(4):358-67. PubMed ID: 12404061
    [Abstract] [Full Text] [Related]

  • 10. High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
    Güntert A, Döbeli H, Bohrmann B.
    Neuroscience; 2006 Dec 01; 143(2):461-75. PubMed ID: 17008022
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  • 11. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 01; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 12. Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.
    Van Broeck B, Vanhoutte G, Pirici D, Van Dam D, Wils H, Cuijt I, Vennekens K, Zabielski M, Michalik A, Theuns J, De Deyn PP, Van der Linden A, Van Broeckhoven C, Kumar-Singh S.
    Neurobiol Aging; 2008 Feb 01; 29(2):241-52. PubMed ID: 17112635
    [Abstract] [Full Text] [Related]

  • 13. Neocortical synaptic bouton number is maintained despite robust amyloid deposition in APP23 transgenic mice.
    Boncristiano S, Calhoun ME, Howard V, Bondolfi L, Kaeser SA, Wiederhold KH, Staufenbiel M, Jucker M.
    Neurobiol Aging; 2005 May 01; 26(5):607-13. PubMed ID: 15708435
    [Abstract] [Full Text] [Related]

  • 14. Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein.
    Lee KW, Lee SH, Kim H, Song JS, Yang SD, Paik SG, Han PL.
    J Neurosci Res; 2004 May 15; 76(4):572-80. PubMed ID: 15114629
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  • 20. Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.
    Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, Kitamoto T.
    Acta Neuropathol; 2007 Jun 15; 113(6):627-36. PubMed ID: 17431643
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