These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

186 related items for PubMed ID: 17938264

  • 21. DNA interstrand crosslinking agents: synthesis, DNA interactions, and cytotoxicity of dimeric achiral seco-amino-CBI and conjugates of achiral seco-amino-CBI with pyrrolobenzodiazepine (PBD).
    Purnell B, Sato A, O'kelley A, Price C, Summerville K, Hudson S, O'hare C, Kiakos K, Asao T, Lee M, Hartley JA.
    Bioorg Med Chem Lett; 2006 Nov 01; 16(21):5677-81. PubMed ID: 16919946
    [Abstract] [Full Text] [Related]

  • 22. Metal cation complexation and activation of reversed CPyI analogues of CC-1065 and duocarmycin SA: partitioning the effects of binding and catalysis.
    Ellis DA, Wolkenberg SE, Boger DL.
    J Am Chem Soc; 2001 Sep 26; 123(38):9299-306. PubMed ID: 11562212
    [Abstract] [Full Text] [Related]

  • 23. Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.
    Plosky B, Samson L, Engelward BP, Gold B, Schlaen B, Millas T, Magnotti M, Schor J, Scicchitano DA.
    DNA Repair (Amst); 2002 Aug 06; 1(8):683-96. PubMed ID: 12509290
    [Abstract] [Full Text] [Related]

  • 24. Photocontrollable sequence-specific DNA alkylation by a pyrrole-imidazole polyamide seco-CBI conjugate.
    Park S, Bando T, Shinohara K, Nishijima S, Sugiyama H.
    Bioconjug Chem; 2011 Feb 16; 22(2):120-4. PubMed ID: 21192678
    [Abstract] [Full Text] [Related]

  • 25. The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.
    Brooks N, McHugh PJ, Lee M, Hartley JA.
    Anticancer Drug Des; 1999 Feb 16; 14(1):11-8. PubMed ID: 10363024
    [Abstract] [Full Text] [Related]

  • 26. Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.
    Tichenor MS, MacMillan KS, Stover JS, Wolkenberg SE, Pavani MG, Zanella L, Zaid AN, Spalluto G, Rayl TJ, Hwang I, Baraldi PG, Boger DL.
    J Am Chem Soc; 2007 Nov 14; 129(45):14092-9. PubMed ID: 17948994
    [Abstract] [Full Text] [Related]

  • 27. Synthesis of pyrrole-imidazole polyamide seco-1-chloromethyl-5-hydroxy-1,2-dihydro-3h-benz[e]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence.
    Takagaki T, Bando T, Sugiyama H.
    J Am Chem Soc; 2012 Aug 08; 134(31):13074-81. PubMed ID: 22799887
    [Abstract] [Full Text] [Related]

  • 28. Characterization of a duocarmycin-DNA adduct-recognizing protein in cancer cells.
    Asai A, Yano K, Mizukami T, Nakano H.
    Cancer Res; 1999 Nov 01; 59(21):5417-20. PubMed ID: 10554008
    [Abstract] [Full Text] [Related]

  • 29. Recognition of DNA adducts by human nucleotide excision repair. Evidence for a thermodynamic probing mechanism.
    Gunz D, Hess MT, Naegeli H.
    J Biol Chem; 1996 Oct 11; 271(41):25089-98. PubMed ID: 8810263
    [Abstract] [Full Text] [Related]

  • 30. Differential effect of duocarmycin A and its novel derivative DU-86 on DNA strand breaks in HeLa S3 cells.
    Okamoto A, Asai A, Saito H, Okabe M, Gomi K.
    Jpn J Cancer Res; 1994 Dec 11; 85(12):1304-11. PubMed ID: 7852193
    [Abstract] [Full Text] [Related]

  • 31. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA.
    Gieseg MA, Matejovic J, Denny WA.
    Anticancer Drug Des; 1999 Feb 11; 14(1):77-84. PubMed ID: 10363030
    [Abstract] [Full Text] [Related]

  • 32. Mechanism of action of AminoCBIs: highly reactive but highly cytotoxic analogues of the duocarmycins.
    Tercel M, Pruijn FB, O'Connor PD, Liyanage HD, Atwell GJ, Alix SM.
    Chembiochem; 2014 Sep 05; 15(13):1998-2006. PubMed ID: 25087870
    [Abstract] [Full Text] [Related]

  • 33. Efficient synthesis of achiral seco-cyclopropylbenz[2,3-e]indoline analogues: [4-amino-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl]ethyl chloride and [4-hydroxy-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl]ethyl chloride.
    Sato A, Scott A, Asao T, Lee M.
    J Org Chem; 2006 Jun 09; 71(12):4692-5. PubMed ID: 16749810
    [Abstract] [Full Text] [Related]

  • 34. Nucleotide excision repair defect influences lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent in the absence of base excision repair.
    Monti P, Iannone R, Campomenosi P, Ciribilli Y, Varadarajan S, Shah D, Menichini P, Gold B, Fronza G.
    Biochemistry; 2004 May 18; 43(19):5592-9. PubMed ID: 15134433
    [Abstract] [Full Text] [Related]

  • 35. The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent.
    Zewail-Foote M, Li VS, Kohn H, Bearss D, Guzman M, Hurley LH.
    Chem Biol; 2001 Nov 18; 8(11):1033-49. PubMed ID: 11731295
    [Abstract] [Full Text] [Related]

  • 36. Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti-cancer agents.
    Damia G, Imperatori L, Stefanini M, D'Incalci M.
    Int J Cancer; 1996 Jun 11; 66(6):779-83. PubMed ID: 8647649
    [Abstract] [Full Text] [Related]

  • 37. Recognition and repair of the CC-1065-(N3-adenine)-DNA adduct by the UVRABC nucleases.
    Tang MS, Lee CS, Doisy R, Ross L, Needham-VanDevanter DR, Hurley LH.
    Biochemistry; 1988 Feb 09; 27(3):893-901. PubMed ID: 2966637
    [Abstract] [Full Text] [Related]

  • 38. Evaluation of functional analogs of CC-1065 and the duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e (C2BI) alkylation subunit.
    Boger DL, Johnson DS, Palanki MS, Kitos PA, Chang J, Dowell P.
    Bioorg Med Chem; 1993 Jul 09; 1(1):27-38. PubMed ID: 8081835
    [Abstract] [Full Text] [Related]

  • 39. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis.
    Boger DL, Santillán A, Searcey M, Brunette SR, Wolkenberg SE, Hedrick MP, Jin Q.
    J Org Chem; 2000 Jun 30; 65(13):4101-11. PubMed ID: 10866627
    [Abstract] [Full Text] [Related]

  • 40. Novel (S)-(-)- and R-(+)-seco-iso-cyclopropylfurano[e]indoline-5,6,7-trimethoxyindole-2-carboxamide (iso-CFI) analogs of duocarmycin C2: synthesis and biological evaluation.
    Purnell B, Lingerfelt B, Scott A, Townes H, Summerville K, Hudson S, Kiakos K, Hartley JA, Lee M.
    Med Chem; 2006 Mar 30; 2(2):139-46. PubMed ID: 16787363
    [Abstract] [Full Text] [Related]

    Page: [Previous] [Next] [New Search]
    of 10.