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Journal Abstract Search

424 related items for PubMed ID: 17938582

  • 1. Molecular basis for the inhibition of p53 by Mdmx.
    Popowicz GM, Czarna A, Rothweiler U, Szwagierczak A, Krajewski M, Weber L, Holak TA.
    Cell Cycle; 2007 Oct 01; 6(19):2386-92. PubMed ID: 17938582
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  • 3. Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction.
    Lemos A, Leão M, Soares J, Palmeira A, Pinto M, Saraiva L, Sousa ME.
    Med Res Rev; 2016 Sep 01; 36(5):789-844. PubMed ID: 27302609
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  • 5. Abnormal MDMX degradation in tumor cells due to ARF deficiency.
    Li X, Gilkes D, Li B, Cheng Q, Pernazza D, Lawrence H, Lawrence N, Chen J.
    Oncogene; 2012 Aug 09; 31(32):3721-32. PubMed ID: 22120712
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  • 6. Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
    Popowicz GM, Czarna A, Holak TA.
    Cell Cycle; 2008 Aug 09; 7(15):2441-3. PubMed ID: 18677113
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  • 7. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
    Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Kubo T, Kaneda M, Ohno H, Osada H, Fujii N.
    Bioorg Med Chem Lett; 2013 Jul 01; 23(13):3802-5. PubMed ID: 23726030
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  • 8. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.
    Xia M, Knezevic D, Tovar C, Huang B, Heimbrook DC, Vassilev LT.
    Cell Cycle; 2008 Jun 01; 7(11):1604-12. PubMed ID: 18520179
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  • 10. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX.
    Hu B, Gilkes DM, Chen J.
    Cancer Res; 2007 Sep 15; 67(18):8810-7. PubMed ID: 17875722
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  • 12. Designing dual inhibitors of Mdm2/MdmX: Unexpected coupling of water with gatekeeper Y100/99.
    Lee XA, Verma C, Sim AYL.
    Proteins; 2017 Aug 15; 85(8):1493-1506. PubMed ID: 28425639
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  • 14. Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.
    Zdzalik M, Pustelny K, Kedracka-Krok S, Huben K, Pecak A, Wladyka B, Jankowski S, Dubin A, Potempa J, Dubin G.
    Cell Cycle; 2010 Nov 15; 9(22):4584-91. PubMed ID: 21088494
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  • 16. A site-directed mutagenesis study of the MdmX RING domain.
    Egorova O, Mis M, Sheng Y.
    Biochem Biophys Res Commun; 2014 May 16; 447(4):696-701. PubMed ID: 24755078
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  • 17. Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay.
    Golestanian S, Sharifi A, Popowicz GM, Azizian H, Foroumadi A, Szwagierczak A, Holak TA, Amanlou M.
    Life Sci; 2016 Jan 15; 145():240-6. PubMed ID: 26746660
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  • 18. Autoinhibition of MDMX by intramolecular p53 mimicry.
    Chen L, Borcherds W, Wu S, Becker A, Schonbrunn E, Daughdrill GW, Chen J.
    Proc Natl Acad Sci U S A; 2015 Apr 14; 112(15):4624-9. PubMed ID: 25825738
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  • 19. In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.
    Bozzi F, Conca E, Laurini E, Posocco P, Lo Sardo A, Jocollè G, Sanfilippo R, Gronchi A, Perrone F, Tamborini E, Pelosi G, Pierotti MA, Maestro R, Pricl S, Pilotti S.
    Lab Invest; 2013 Nov 14; 93(11):1232-40. PubMed ID: 24018792
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  • 20. On the interaction mechanisms of a p53 peptide and nutlin with the MDM2 and MDMX proteins: a Brownian dynamics study.
    ElSawy KM, Verma CS, Joseph TL, Lane DP, Twarock R, Caves LS.
    Cell Cycle; 2013 Feb 01; 12(3):394-404. PubMed ID: 23324352
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