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421 related items for PubMed ID: 17942461

  • 1. Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53.
    Hockley SL, Arlt VM, Jahnke G, Hartwig A, Giddings I, Phillips DH.
    Carcinogenesis; 2008 Jan; 29(1):202-10. PubMed ID: 17942461
    [Abstract] [Full Text] [Related]

  • 2. Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.
    Hockley SL, Arlt VM, Brewer D, Giddings I, Phillips DH.
    BMC Genomics; 2006 Oct 16; 7():260. PubMed ID: 17042939
    [Abstract] [Full Text] [Related]

  • 3. Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells.
    Akerman GS, Rosenzweig BA, Domon OE, McGarrity LJ, Blankenship LR, Tsai CA, Culp SJ, MacGregor JT, Sistare FD, Chen JJ, Morris SM.
    Mutat Res; 2004 May 18; 549(1-2):43-64. PubMed ID: 15120962
    [Abstract] [Full Text] [Related]

  • 4. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA, Zhu Q, El-Mahdy M, Venkatachalam S, Wani AA.
    Cancer Res; 2000 Apr 15; 60(8):2273-80. PubMed ID: 10786695
    [Abstract] [Full Text] [Related]

  • 5. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ.
    Carcinogenesis; 2007 Jan 15; 28(1):207-14. PubMed ID: 16885195
    [Abstract] [Full Text] [Related]

  • 6. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC, Tsou TC.
    Toxicol In Vitro; 2009 Aug 15; 23(5):897-905. PubMed ID: 19470404
    [Abstract] [Full Text] [Related]

  • 7. Effects of cadmium(II) on (+/-)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage response in human fibroblasts and DNA repair: a possible mechanism of cadmium's cogenotoxicity.
    Mukherjee JJ, Gupta SK, Kumar S, Sikka HC.
    Chem Res Toxicol; 2004 Mar 15; 17(3):287-93. PubMed ID: 15025498
    [Abstract] [Full Text] [Related]

  • 8. Alterations in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible associations with cytochrome P450 metabolism and increased protein tyrosine phosphorylation.
    Mounho BJ, Burchiel SW.
    Toxicol Appl Pharmacol; 1998 Mar 15; 149(1):80-9. PubMed ID: 9512730
    [Abstract] [Full Text] [Related]

  • 9. PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells.
    Burdick AD, Ivnitski-Steele ID, Lauer FT, Burchiel SW.
    Carcinogenesis; 2006 Nov 15; 27(11):2331-40. PubMed ID: 16774943
    [Abstract] [Full Text] [Related]

  • 10. Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis.
    Huovinen M, Loikkanen J, Myllynen P, Vähäkangas KH.
    Toxicol In Vitro; 2011 Aug 15; 25(5):1007-17. PubMed ID: 21457773
    [Abstract] [Full Text] [Related]

  • 11. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
    Zhan DJ, Heflich RH, Fu PP.
    Environ Mol Mutagen; 1996 Aug 15; 27(1):19-29. PubMed ID: 8625944
    [Abstract] [Full Text] [Related]

  • 12. [Study on lung carcinogenesis associated genes in human lung squamous cell carcinoma and malignant transformation of human bronchial epithelial cells induced by carcinogen].
    Lü JC, Chen JK, Ji WD, Jiang YG, Shi LY, Wu ZL, He M, Zeng BH.
    Zhonghua Yi Xue Za Zhi; 2003 Dec 25; 83(24):2146-51. PubMed ID: 14720424
    [Abstract] [Full Text] [Related]

  • 13. Benzo(a)pyrene increases phosphorylation of p53 at serine 392 in relation to p53 induction and cell death in MCF-7 cells.
    Tampio M, Loikkanen J, Myllynen P, Mertanen A, Vähäkangas KH.
    Toxicol Lett; 2008 May 30; 178(3):152-9. PubMed ID: 18440733
    [Abstract] [Full Text] [Related]

  • 14. Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.
    Dreij K, Seidel A, Jernström B.
    Chem Res Toxicol; 2005 Apr 30; 18(4):655-64. PubMed ID: 15833025
    [Abstract] [Full Text] [Related]

  • 15. Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).
    Shinmura K, Iwaizumi M, Igarashi H, Nagura K, Yamada H, Suzuki M, Fukasawa K, Sugimura H.
    J Pathol; 2008 Nov 30; 216(3):365-74. PubMed ID: 18788085
    [Abstract] [Full Text] [Related]

  • 16. Early whole-genome transcriptional response induced by benzo[a]pyrene diol epoxide in a normal human cell line.
    Lu X, Shao J, Li H, Yu Y.
    Genomics; 2009 Apr 30; 93(4):332-42. PubMed ID: 19150397
    [Abstract] [Full Text] [Related]

  • 17. High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Rojas M, Marie B, Vignaud JM, Martinet N, Siat J, Grosdidier G, Cascorbi I, Alexandrov K.
    Cancer Lett; 2004 Apr 30; 207(2):157-63. PubMed ID: 15072824
    [Abstract] [Full Text] [Related]

  • 18. Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.
    Khan QA, Anderson LM.
    Toxicol Appl Pharmacol; 2001 Jun 01; 173(2):105-13. PubMed ID: 11384212
    [Abstract] [Full Text] [Related]

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  • 20. Temporal gene expression changes induced by a low concentration of benzo[a]pyrene diol epoxide in a normal human cell line.
    Lu X, Shao J, Li H, Yu Y.
    Mutat Res; 2010 Feb 03; 684(1-2):74-80. PubMed ID: 20018196
    [Abstract] [Full Text] [Related]

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