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Journal Abstract Search

126 related items for PubMed ID: 17949679

  • 1. Positional dependence of non-native polar mutations on folding of CFTR helical hairpins.
    Wehbi H, Gasmi-Seabrook G, Choi MY, Deber CM.
    Biochim Biophys Acta; 2008 Jan; 1778(1):79-87. PubMed ID: 17949679
    [Abstract] [Full Text] [Related]

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  • 3. The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bonds.
    Loo TW, Clarke DM.
    Biochem Pharmacol; 2014 Mar 01; 88(1):46-57. PubMed ID: 24412276
    [Abstract] [Full Text] [Related]

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  • 5. Role of the extracellular loop in the folding of a CFTR transmembrane helical hairpin.
    Wehbi H, Rath A, Glibowicka M, Deber CM.
    Biochemistry; 2007 Jun 19; 46(24):7099-106. PubMed ID: 17516627
    [Abstract] [Full Text] [Related]

  • 6. Structural basis for misfolding at a disease phenotypic position in CFTR: comparison of TM3/4 helix-loop-helix constructs with TM4 peptides.
    Mulvihill CM, Deber CM.
    Biochim Biophys Acta; 2012 Jan 19; 1818(1):49-54. PubMed ID: 21996038
    [Abstract] [Full Text] [Related]

  • 7. Structural effects of extracellular loop mutations in CFTR helical hairpins.
    Chang YH, Stone TA, Chin S, Glibowicka M, Bear CE, Deber CM.
    Biochim Biophys Acta Biomembr; 2018 May 19; 1860(5):1092-1098. PubMed ID: 29307731
    [Abstract] [Full Text] [Related]

  • 8. Interhelical hydrogen bonds in the CFTR membrane domain.
    Therien AG, Grant FE, Deber CM.
    Nat Struct Biol; 2001 Jul 19; 8(7):597-601. PubMed ID: 11427889
    [Abstract] [Full Text] [Related]

  • 9. CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor.
    Krainer G, Schenkel M, Hartmann A, Ravamehr-Lake D, Deber CM, Schlierf M.
    J Biol Chem; 2020 Feb 14; 295(7):1985-1991. PubMed ID: 31882543
    [Abstract] [Full Text] [Related]

  • 10. Loop sequence dictates the secondary structure of a human membrane protein hairpin.
    Nadeau VG, Deber CM.
    Biochemistry; 2013 Apr 09; 52(14):2419-26. PubMed ID: 23488803
    [Abstract] [Full Text] [Related]

  • 11. Impact of cholesterol and Lumacaftor on the folding of CFTR helical hairpins.
    Schenkel M, Ravamehr-Lake D, Czerniak T, Saenz JP, Krainer G, Schlierf M, Deber CM.
    Biochim Biophys Acta Biomembr; 2023 Jan 01; 1865(1):184078. PubMed ID: 36279907
    [Abstract] [Full Text] [Related]

  • 12. Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): regulation by the amino terminal transmembrane sequences.
    Chen M, Zhang JT.
    Biochemistry; 1999 Apr 27; 38(17):5471-7. PubMed ID: 10220334
    [Abstract] [Full Text] [Related]

  • 13. Hydrophobic helical hairpins: design and packing interactions in membrane environments.
    Johnson RM, Heslop CL, Deber CM.
    Biochemistry; 2004 Nov 16; 43(45):14361-9. PubMed ID: 15533040
    [Abstract] [Full Text] [Related]

  • 14. Transmembrane domain of cystic fibrosis transmembrane conductance regulator: design, characterization, and secondary structure of synthetic peptides m1-m6.
    Wigley WC, Vijayakumar S, Jones JD, Slaughter C, Thomas PJ.
    Biochemistry; 1998 Jan 20; 37(3):844-53. PubMed ID: 9454574
    [Abstract] [Full Text] [Related]

  • 15. The DeltaF508 mutation disrupts packing of the transmembrane segments of the cystic fibrosis transmembrane conductance regulator.
    Chen EY, Bartlett MC, Loo TW, Clarke DM.
    J Biol Chem; 2004 Sep 17; 279(38):39620-7. PubMed ID: 15272010
    [Abstract] [Full Text] [Related]

  • 16. Interhelical packing in detergent micelles. Folding of a cystic fibrosis transmembrane conductance regulator construct.
    Therien AG, Deber CM.
    J Biol Chem; 2002 Feb 22; 277(8):6067-72. PubMed ID: 11748233
    [Abstract] [Full Text] [Related]

  • 17. Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.
    Massiah MA, Ko YH, Pedersen PL, Mildvan AS.
    Biochemistry; 1999 Jun 08; 38(23):7453-61. PubMed ID: 10360942
    [Abstract] [Full Text] [Related]

  • 18. Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: toward understanding topological rules for membrane assembly of polytopic membrane proteins.
    Zhang JT, Chen M, Han E, Wang C.
    Mol Biol Cell; 1998 Apr 08; 9(4):853-63. PubMed ID: 9529383
    [Abstract] [Full Text] [Related]

  • 19. Detergent binding explains anomalous SDS-PAGE migration of membrane proteins.
    Rath A, Glibowicka M, Nadeau VG, Chen G, Deber CM.
    Proc Natl Acad Sci U S A; 2009 Feb 10; 106(6):1760-5. PubMed ID: 19181854
    [Abstract] [Full Text] [Related]

  • 20. Cystic fibrosis transmembrane conductance regulator: expression and helicity of a double membrane-spanning segment.
    Peng S, Liu LP, Emili AQ, Deber CM.
    FEBS Lett; 1998 Jul 10; 431(1):29-33. PubMed ID: 9684859
    [Abstract] [Full Text] [Related]

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