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Journal Abstract Search

128 related items for PubMed ID: 17951386

  • 1. Transmembrane helix 12 of the Staphylococcus aureus multidrug transporter QacA lines the bivalent cationic drug binding pocket.
    Hassan KA, Skurray RA, Brown MH.
    J Bacteriol; 2007 Dec; 189(24):9131-4. PubMed ID: 17951386
    [Abstract] [Full Text] [Related]

  • 2. Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA.
    Hassan KA, Galea M, Wu J, Mitchell BA, Skurray RA, Brown MH.
    FEMS Microbiol Lett; 2006 Oct; 263(1):76-85. PubMed ID: 16958854
    [Abstract] [Full Text] [Related]

  • 3. Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA.
    Xu Z, O'Rourke BA, Skurray RA, Brown MH.
    J Biol Chem; 2006 Jan 13; 281(2):792-9. PubMed ID: 16282328
    [Abstract] [Full Text] [Related]

  • 4. Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity.
    Paulsen IT, Brown MH, Littlejohn TG, Mitchell BA, Skurray RA.
    Proc Natl Acad Sci U S A; 1996 Apr 16; 93(8):3630-5. PubMed ID: 8622987
    [Abstract] [Full Text] [Related]

  • 5. The role of TMS 12 in the staphylococcal multidrug efflux protein QacA.
    Dashtbani-Roozbehani A, Chitsaz M, Brown MH.
    J Antimicrob Chemother; 2023 Jun 01; 78(6):1522-1531. PubMed ID: 37100459
    [Abstract] [Full Text] [Related]

  • 6. Staphylococcal multidrug efflux protein QacA.
    Brown MH, Skurray RA.
    J Mol Microbiol Biotechnol; 2001 Apr 01; 3(2):163-70. PubMed ID: 11321569
    [Abstract] [Full Text] [Related]

  • 7. Fluoroquinolone efflux by the plasmid-mediated multidrug efflux pump QacB variant QacBIII in Staphylococcus aureus.
    Nakaminami H, Noguchi N, Sasatsu M.
    Antimicrob Agents Chemother; 2010 Oct 01; 54(10):4107-11. PubMed ID: 20660673
    [Abstract] [Full Text] [Related]

  • 8. Analysis of tryptophan residues in the staphylococcal multidrug transporter QacA reveals long-distance functional associations of residues on opposite sides of the membrane.
    Hassan KA, Souhani T, Skurray RA, Brown MH.
    J Bacteriol; 2008 Apr 01; 190(7):2441-9. PubMed ID: 18223078
    [Abstract] [Full Text] [Related]

  • 9. Dissection of Protonation Sites for Antibacterial Recognition and Transport in QacA, a Multi-Drug Efflux Transporter.
    Majumder P, Khare S, Athreya A, Hussain N, Gulati A, Penmatsa A.
    J Mol Biol; 2019 May 17; 431(11):2163-2179. PubMed ID: 30910733
    [Abstract] [Full Text] [Related]

  • 10. Biochemical characterization of the multidrug regulator QacR distinguishes residues that are crucial to multidrug binding and induction of qacA transcription.
    Peters KM, Sharbeen G, Theis T, Skurray RA, Brown MH.
    Biochemistry; 2009 Oct 20; 48(41):9794-800. PubMed ID: 19761200
    [Abstract] [Full Text] [Related]

  • 11. Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations.
    Mitchell BA, Paulsen IT, Brown MH, Skurray RA.
    J Biol Chem; 1999 Feb 05; 274(6):3541-8. PubMed ID: 9920900
    [Abstract] [Full Text] [Related]

  • 12. Cryo-EM structure of antibacterial efflux transporter QacA from Staphylococcus aureus reveals a novel extracellular loop with allosteric role.
    Majumder P, Ahmed S, Ahuja P, Athreya A, Ranjan R, Penmatsa A.
    EMBO J; 2023 Aug 15; 42(16):e113418. PubMed ID: 37458117
    [Abstract] [Full Text] [Related]

  • 13. Low-level resistance of Staphylococcus aureus to thrombin-induced platelet microbicidal protein 1 in vitro associated with qacA gene carriage is independent of multidrug efflux pump activity.
    Bayer AS, Kupferwasser LI, Brown MH, Skurray RA, Grkovic S, Jones T, Mukhopadhay K, Yeaman MR.
    Antimicrob Agents Chemother; 2006 Jul 15; 50(7):2448-54. PubMed ID: 16801425
    [Abstract] [Full Text] [Related]

  • 14. Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization.
    Truong-Bolduc QC, Wang Y, Hooper DC.
    Infect Immun; 2021 Apr 16; 89(5):. PubMed ID: 33619028
    [Abstract] [Full Text] [Related]

  • 15. Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA.
    Wu J, Hassan KA, Skurray RA, Brown MH.
    BMC Microbiol; 2008 Sep 16; 8():147. PubMed ID: 18793443
    [Abstract] [Full Text] [Related]

  • 16. Interactions of the QacR multidrug-binding protein with structurally diverse ligands: implications for the evolution of the binding pocket.
    Grkovic S, Hardie KM, Brown MH, Skurray RA.
    Biochemistry; 2003 Dec 30; 42(51):15226-36. PubMed ID: 14690433
    [Abstract] [Full Text] [Related]

  • 17. QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA.
    Grkovic S, Brown MH, Roberts NJ, Paulsen IT, Skurray RA.
    J Biol Chem; 1998 Jul 17; 273(29):18665-73. PubMed ID: 9660841
    [Abstract] [Full Text] [Related]

  • 18. GraXSR proteins interact with the VraFG ABC transporter to form a five-component system required for cationic antimicrobial peptide sensing and resistance in Staphylococcus aureus.
    Falord M, Karimova G, Hiron A, Msadek T.
    Antimicrob Agents Chemother; 2012 Feb 17; 56(2):1047-58. PubMed ID: 22123691
    [Abstract] [Full Text] [Related]

  • 19. Analysis on distribution and genomic diversity of high-level antiseptic resistance genes qacA and qacB in human clinical isolates of Staphylococcus aureus.
    Alam MM, Kobayashi N, Uehara N, Watanabe N.
    Microb Drug Resist; 2003 Feb 17; 9(2):109-21. PubMed ID: 12820795
    [Abstract] [Full Text] [Related]

  • 20. Promiscuity in the geometry of electrostatic interactions between the Escherichia coli multidrug resistance transporter MdfA and cationic substrates.
    Adler J, Bibi E.
    J Biol Chem; 2005 Jan 28; 280(4):2721-9. PubMed ID: 15557318
    [Abstract] [Full Text] [Related]

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