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Journal Abstract Search

626 related items for PubMed ID: 17961921

  • 1. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H, Tabira T.
    Neurosci Lett; 2007 Nov 27; 428(2-3):103-8. PubMed ID: 17961921
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  • 3. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M, Schnitzler CE, Vasilieva N, Leung D, Choe H.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9712-7. PubMed ID: 10931940
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  • 4. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb 15; 100(3):802-9. PubMed ID: 17156133
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  • 5. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
    Sauder JM, Arthur JW, Dunbrack RL.
    J Mol Biol; 2000 Jul 07; 300(2):241-8. PubMed ID: 10873463
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  • 7. Evidence for dimeric BACE-mediated APP processing.
    Jin S, Agerman K, Kolmodin K, Gustafsson E, Dahlqvist C, Jureus A, Liu G, Fälting J, Berg S, Lundkvist J, Lendahl U.
    Biochem Biophys Res Commun; 2010 Feb 26; 393(1):21-7. PubMed ID: 20097169
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  • 9. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
    Fu H, Dou J, Li W, Cui W, Mak S, Hu Q, Luo J, Lam CS, Pang Y, Youdim MB, Han Y.
    Eur J Pharmacol; 2009 Nov 25; 623(1-3):14-21. PubMed ID: 19765582
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  • 10. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA, Liu WW, Todd SA, Coulson DT, Murphy S, Irvine GB, Passmore AP.
    Biochem Soc Trans; 2005 Nov 25; 33(Pt 5):1096-100. PubMed ID: 16246054
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  • 11. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.
    Mol Vis; 2003 May 01; 9():179-83. PubMed ID: 12740567
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  • 14. Amyloid precursor protein and BACE function as oligomers.
    Multhaup G.
    Neurodegener Dis; 2006 May 01; 3(4-5):270-4. PubMed ID: 17047367
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  • 15. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.
    Proc Natl Acad Sci U S A; 2006 Nov 21; 103(47):17967-72. PubMed ID: 17098871
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  • 16. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH, O'Neill C.
    Biochem Soc Trans; 2007 Jun 21; 35(Pt 3):574-6. PubMed ID: 17511655
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  • 17. Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.
    Parsons RB, Austen BM.
    Biochem Soc Trans; 2007 Nov 21; 35(Pt 5):974-9. PubMed ID: 17956258
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  • 18. Identification of a novel aspartic protease (Asp 2) as beta-secretase.
    Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G.
    Mol Cell Neurosci; 1999 Dec 21; 14(6):419-27. PubMed ID: 10656250
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  • 19. Hydrogen sulfide reduces mRNA and protein levels of β-site amyloid precursor protein cleaving enzyme 1 in PC12 cells.
    Zhang H, Gao Y, Zhao F, Dai Z, Meng T, Tu S, Yan Y.
    Neurochem Int; 2011 Feb 21; 58(2):169-75. PubMed ID: 21095213
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  • 20. Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.
    Boddapati S, Levites Y, Sierks MR.
    J Mol Biol; 2011 Jan 14; 405(2):436-47. PubMed ID: 21073877
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