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Journal Abstract Search

277 related items for PubMed ID: 17967933

  • 1. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
    Acharya P, O'Connor MP, Polli JW, Ayrton A, Ellens H, Bentz J.
    Drug Metab Dispos; 2008 Feb; 36(2):452-60. PubMed ID: 17967933
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  • 2. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.
    Acharya P, Tran TT, Polli JW, Ayrton A, Ellens H, Bentz J.
    Biochemistry; 2006 Dec 26; 45(51):15505-19. PubMed ID: 17176072
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  • 4. Extrapolation of Elementary Rate Constants of P-glycoprotein-Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells.
    Meng Z, Ellens H, Bentz J.
    Drug Metab Dispos; 2017 Feb 26; 45(2):190-197. PubMed ID: 27856526
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  • 6. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Taub ME, Podila L, Ely D, Almeida I.
    Drug Metab Dispos; 2005 Nov 26; 33(11):1679-87. PubMed ID: 16093365
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  • 7. If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?
    Lumen AA, Acharya P, Polli JW, Ayrton A, Ellens H, Bentz J.
    Drug Metab Dispos; 2010 Feb 26; 38(2):260-9. PubMed ID: 19889884
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  • 8. The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.
    Tran TT, Mittal A, Aldinger T, Polli JW, Ayrton A, Ellens H, Bentz J.
    Biophys J; 2005 Jan 26; 88(1):715-38. PubMed ID: 15501934
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  • 11. Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
    Tanigawara Y, Okamura N, Hirai M, Yasuhara M, Ueda K, Kioka N, Komano T, Hori R.
    J Pharmacol Exp Ther; 1992 Nov 26; 263(2):840-5. PubMed ID: 1359120
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  • 14. Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.
    Keogh JP, Kunta JR.
    Eur J Pharm Sci; 2006 Apr 26; 27(5):543-54. PubMed ID: 16406207
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  • 17. Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents.
    Garner CE, Solon E, Lai CM, Lin J, Luo G, Jones K, Duan J, Decicco CP, Maduskuie T, Mercer SE, Gan LS, Qian M, Prakash S, Shen HS, Lee FW.
    Drug Metab Dispos; 2008 Jun 26; 36(6):1102-10. PubMed ID: 18347085
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  • 18. Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport.
    Varma MV, Sateesh K, Panchagnula R.
    Mol Pharm; 2005 Jun 26; 2(1):12-21. PubMed ID: 15804173
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  • 20. Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data.
    Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J.
    Drug Metab Dispos; 2018 Mar 26; 46(3):279-290. PubMed ID: 29317410
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