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Journal Abstract Search

257 related items for PubMed ID: 17968948

  • 1. Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis.
    Majumdar MK, Askew R, Schelling S, Stedman N, Blanchet T, Hopkins B, Morris EA, Glasson SS.
    Arthritis Rheum; 2007 Nov; 56(11):3670-4. PubMed ID: 17968948
    [Abstract] [Full Text] [Related]

  • 2. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.
    Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, Flannery CR, Kanki K, Wang E, Peluso D, Yang Z, Majumdar MK, Morris EA.
    Arthritis Rheum; 2004 Aug; 50(8):2547-58. PubMed ID: 15334469
    [Abstract] [Full Text] [Related]

  • 3. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.
    Song RH, Tortorella MD, Malfait AM, Alston JT, Yang Z, Arner EC, Griggs DW.
    Arthritis Rheum; 2007 Feb; 56(2):575-85. PubMed ID: 17265492
    [Abstract] [Full Text] [Related]

  • 4. ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.
    Verma P, Dalal K.
    J Cell Biochem; 2011 Dec; 112(12):3507-14. PubMed ID: 21815191
    [Abstract] [Full Text] [Related]

  • 5. Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5.
    Rogerson FM, Stanton H, East CJ, Golub SB, Tutolo L, Farmer PJ, Fosang AJ.
    Arthritis Rheum; 2008 Jun; 58(6):1664-73. PubMed ID: 18512787
    [Abstract] [Full Text] [Related]

  • 6. Aggrecanase and aggrecan degradation in osteoarthritis: a review.
    Huang K, Wu LD.
    J Int Med Res; 2008 Jun; 36(6):1149-60. PubMed ID: 19094423
    [Abstract] [Full Text] [Related]

  • 7. Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice.
    Ilic MZ, East CJ, Rogerson FM, Fosang AJ, Handley CJ.
    J Biol Chem; 2007 Dec 28; 282(52):37420-8. PubMed ID: 17938173
    [Abstract] [Full Text] [Related]

  • 8. Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis.
    Kadri A, Ea HK, Bazille C, Hannouche D, Lioté F, Cohen-Solal ME.
    Arthritis Rheum; 2008 Aug 28; 58(8):2379-86. PubMed ID: 18668550
    [Abstract] [Full Text] [Related]

  • 9. Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy.
    Clements KM, Price JS, Chambers MG, Visco DM, Poole AR, Mason RM.
    Arthritis Rheum; 2003 Dec 28; 48(12):3452-63. PubMed ID: 14673996
    [Abstract] [Full Text] [Related]

  • 10. ADAMTS-4_v1 is a splice variant of ADAMTS-4 that is expressed as a protein in human synovium and cleaves aggrecan at the interglobular domain.
    Wainwright SD, Bondeson J, Caterson B, Hughes CE.
    Arthritis Rheum; 2013 Nov 28; 65(11):2866-75. PubMed ID: 23897278
    [Abstract] [Full Text] [Related]

  • 11. [Research progress of a disintegrin and metalloproteinase with thrombospondin motif 4 and 5 in osteoarthritis].
    Ji Q, Zhang Q, Wang Y.
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2013 Sep 28; 27(9):1080-4. PubMed ID: 24279019
    [Abstract] [Full Text] [Related]

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  • 13. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    He Y, Zheng Q, Jiang M, Sun S, Christiansen TG, Kassem M, Karsdal MA, Bay-Jensen AC.
    PLoS One; 2015 Sep 28; 10(4):e0122700. PubMed ID: 25909781
    [Abstract] [Full Text] [Related]

  • 14. The development and characterization of a competitive ELISA for measuring active ADAMTS-4 in a bovine cartilage ex vivo model.
    He Y, Zheng Q, Simonsen O, Petersen KK, Christiansen TG, Karsdal MA, Bay-Jensen AC.
    Matrix Biol; 2013 Apr 24; 32(3-4):143-51. PubMed ID: 23295731
    [Abstract] [Full Text] [Related]

  • 15. Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system.
    Powell AJ, Little CB, Hughes CE.
    Arthritis Rheum; 2007 Sep 24; 56(9):3010-9. PubMed ID: 17763444
    [Abstract] [Full Text] [Related]

  • 16. ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury.
    Demircan K, Topcu V, Takigawa T, Akyol S, Yonezawa T, Ozturk G, Ugurcu V, Hasgul R, Yigitoglu MR, Akyol O, McCulloch DR, Hirohata S.
    Biomed Res Int; 2014 Sep 24; 2014():693746. PubMed ID: 25101296
    [Abstract] [Full Text] [Related]

  • 17. Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice.
    Imada K, Lin N, Liu C, Lu A, Chen W, Yano M, Sato T, Ito A.
    Biochem Biophys Res Commun; 2008 Aug 22; 373(2):181-5. PubMed ID: 18541144
    [Abstract] [Full Text] [Related]

  • 18. ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes.
    Botter SM, Glasson SS, Hopkins B, Clockaerts S, Weinans H, van Leeuwen JP, van Osch GJ.
    Osteoarthritis Cartilage; 2009 May 22; 17(5):636-45. PubMed ID: 19010693
    [Abstract] [Full Text] [Related]

  • 19. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro.
    Stanton H, Rogerson FM, East CJ, Golub SB, Lawlor KE, Meeker CT, Little CB, Last K, Farmer PJ, Campbell IK, Fourie AM, Fosang AJ.
    Nature; 2005 Mar 31; 434(7033):648-52. PubMed ID: 15800625
    [Abstract] [Full Text] [Related]

  • 20. Increased serum ADAMTS-4 in knee osteoarthritis: a potential indicator for the diagnosis of osteoarthritis in early stages.
    Li W, Du C, Wang H, Zhang C.
    Genet Mol Res; 2014 Nov 14; 13(4):9642-9. PubMed ID: 25501175
    [Abstract] [Full Text] [Related]

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