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Journal Abstract Search

146 related items for PubMed ID: 17986868

  • 1.
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  • 2. Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
    Atwal RS, Xia J, Pinchev D, Taylor J, Epand RM, Truant R.
    Hum Mol Genet; 2007 Nov 01; 16(21):2600-15. PubMed ID: 17704510
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  • 3. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
    Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW, Lee ST, Kim M, Ryu H, Jung YK.
    Hum Mol Genet; 2012 Jan 01; 21(1):101-14. PubMed ID: 21954231
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  • 5. Hypothesis: Huntingtin may function in membrane association and vesicular trafficking.
    Truant R, Atwal R, Burtnik A.
    Biochem Cell Biol; 2006 Dec 01; 84(6):912-7. PubMed ID: 17215878
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  • 6. Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.
    Reijonen S, Putkonen N, Nørremølle A, Lindholm D, Korhonen L.
    Exp Cell Res; 2008 Mar 10; 314(5):950-60. PubMed ID: 18255062
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  • 8. Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's disease.
    Vidal R, Caballero B, Couve A, Hetz C.
    Curr Mol Med; 2011 Feb 10; 11(1):1-12. PubMed ID: 21189122
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  • 10. Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.
    Passani LA, Bedford MT, Faber PW, McGinnis KM, Sharp AH, Gusella JF, Vonsattel JP, MacDonald ME.
    Hum Mol Genet; 2000 Sep 01; 9(14):2175-82. PubMed ID: 10958656
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  • 11. Huntingtin facilitates polycomb repressive complex 2.
    Seong IS, Woda JM, Song JJ, Lloret A, Abeyrathne PD, Woo CJ, Gregory G, Lee JM, Wheeler VC, Walz T, Kingston RE, Gusella JF, Conlon RA, MacDonald ME.
    Hum Mol Genet; 2010 Feb 15; 19(4):573-83. PubMed ID: 19933700
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  • 12. Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease.
    Truant R, Atwal RS, Burtnik A.
    Prog Neurobiol; 2007 Nov 15; 83(4):211-27. PubMed ID: 17240517
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  • 13. Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy.
    Ravikumar B, Stewart A, Kita H, Kato K, Duden R, Rubinsztein DC.
    Hum Mol Genet; 2003 May 01; 12(9):985-94. PubMed ID: 12700167
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  • 14. Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease.
    Miki Y, Tanji K, Mori F, Wakabayashi K.
    Neurobiol Dis; 2015 Feb 01; 74():25-31. PubMed ID: 25449906
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  • 15. Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
    Cho KJ, Lee BI, Cheon SY, Kim HW, Kim HJ, Kim GW.
    Neuroscience; 2009 Nov 10; 163(4):1128-34. PubMed ID: 19646509
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  • 16. Huntington's disease: degradation of mutant huntingtin by autophagy.
    Sarkar S, Rubinsztein DC.
    FEBS J; 2008 Sep 10; 275(17):4263-70. PubMed ID: 18637946
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  • 17. Polyglutamine expansion in huntingtin alters its interaction with phospholipids.
    Kegel KB, Sapp E, Alexander J, Valencia A, Reeves P, Li X, Masso N, Sobin L, Aronin N, DiFiglia M.
    J Neurochem; 2009 Sep 10; 110(5):1585-97. PubMed ID: 19566678
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  • 18. Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.
    Valencia A, Reeves PB, Sapp E, Li X, Alexander J, Kegel KB, Chase K, Aronin N, DiFiglia M.
    J Neurosci Res; 2010 Jan 10; 88(1):179-90. PubMed ID: 19642201
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  • 19. Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane.
    Brandstaetter H, Kruppa AJ, Buss F.
    Dis Model Mech; 2014 Dec 10; 7(12):1335-40. PubMed ID: 25368120
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  • 20. Huntingtin-protein interactions and the pathogenesis of Huntington's disease.
    Li SH, Li XJ.
    Trends Genet; 2004 Mar 10; 20(3):146-54. PubMed ID: 15036808
    [Abstract] [Full Text] [Related]

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