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309 related items for PubMed ID: 17991476

  • 1. Development and characterization of beta-secretase monolithic micro-immobilized enzyme reactor for on-line high-performance liquid chromatography studies.
    Mancini F, Naldi M, Cavrini V, Andrisano V.
    J Chromatogr A; 2007 Dec 21; 1175(2):217-26. PubMed ID: 17991476
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  • 2. Development of a liquid chromatographic system with fluorescent detection for beta-secretase immobilized enzyme reactor on-line enzymatic studies.
    Mancini F, Andrisano V.
    J Pharm Biomed Anal; 2010 Jul 08; 52(3):355-61. PubMed ID: 19674859
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  • 6. Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library.
    De Simone A, Mancini F, Cosconati S, Marinelli L, La Pietra V, Novellino E, Andrisano V.
    J Pharm Biomed Anal; 2013 Jan 25; 73():131-4. PubMed ID: 22502908
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  • 7. Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.
    Boddapati S, Levites Y, Sierks MR.
    J Mol Biol; 2011 Jan 14; 405(2):436-47. PubMed ID: 21073877
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  • 8. Identification of beta-secretase-like activity using a mass spectrometry-based assay system.
    Grüninger-Leitch F, Berndt P, Langen H, Nelboeck P, Döbeli H.
    Nat Biotechnol; 2000 Jan 14; 18(1):66-70. PubMed ID: 10625394
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  • 9. An inhibitor binding pocket distinct from the catalytic active site on human beta-APP cleaving enzyme.
    Kornacker MG, Lai Z, Witmer M, Ma J, Hendrick J, Lee VG, Riexinger DJ, Mapelli C, Metzler W, Copeland RA.
    Biochemistry; 2005 Aug 30; 44(34):11567-73. PubMed ID: 16114893
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  • 10. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.
    J Pharmacol Exp Ther; 2008 Mar 30; 324(3):957-69. PubMed ID: 18156464
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  • 11. Expression, purification and activity measurement of soluble BACE protein in E.coli.
    Wei XC, Li H, Ji JG, Li R, Ren YF, Feng JH, Hao FY.
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2002 Jul 30; 34(4):498-501. PubMed ID: 12098775
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  • 12. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H, Tabira T.
    Neurosci Lett; 2007 Nov 27; 428(2-3):103-8. PubMed ID: 17961921
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  • 15. Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid peptide as fluorogenic substrate.
    De Simone A, Seidl C, Santos CA, Andrisano V.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Mar 15; 953-954():108-14. PubMed ID: 24590190
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  • 16. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.
    J Pharmacol Exp Ther; 2008 Aug 15; 326(2):502-13. PubMed ID: 18499745
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  • 17. Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity.
    Fu H, Li W, Luo J, Lee NT, Li M, Tsim KW, Pang Y, Youdim MB, Han Y.
    Biochem Biophys Res Commun; 2008 Feb 15; 366(3):631-6. PubMed ID: 18039469
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  • 18. Application of quantitative LC-MS surrogate peptide methodology in the analysis of the amyloid beta peptide (Abeta) biosynthetic intermediate protein APP-betaCTF.
    Cantone JL, Xu-Lin A, Toyn JH, Drexler DM.
    J Neurosci Methods; 2009 Jun 15; 180(2):255-60. PubMed ID: 19464516
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  • 19. Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.
    Parsons RB, Austen BM.
    Biochem Soc Trans; 2007 Nov 15; 35(Pt 5):974-9. PubMed ID: 17956258
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  • 20. Evidence for dimeric BACE-mediated APP processing.
    Jin S, Agerman K, Kolmodin K, Gustafsson E, Dahlqvist C, Jureus A, Liu G, Fälting J, Berg S, Lundkvist J, Lendahl U.
    Biochem Biophys Res Commun; 2010 Feb 26; 393(1):21-7. PubMed ID: 20097169
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