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271 related items for PubMed ID: 17991869

  • 1. BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.
    Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.
    Mol Pharmacol; 2008 Feb; 73(2):419-30. PubMed ID: 17991869
    [Abstract] [Full Text] [Related]

  • 2. Requirement of a functional spindle checkpoint for arsenite-induced apoptosis.
    Wu YC, Yen WY, Yih LH.
    J Cell Biochem; 2008 Oct 15; 105(3):678-87. PubMed ID: 18668508
    [Abstract] [Full Text] [Related]

  • 3. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.
    Ha GH, Baek KH, Kim HS, Jeong SJ, Kim CM, McKeon F, Lee CW.
    Cancer Res; 2007 Aug 01; 67(15):7155-64. PubMed ID: 17671183
    [Abstract] [Full Text] [Related]

  • 4. Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.
    Mulligan JM, Greene LM, Cloonan S, Mc Gee MM, Onnis V, Campiani G, Fattorusso C, Lawler M, Williams DC, Zisterer DM.
    Mol Pharmacol; 2006 Jul 01; 70(1):60-70. PubMed ID: 16571652
    [Abstract] [Full Text] [Related]

  • 5. p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase.
    Wu H, Lan Z, Li W, Wu S, Weinstein J, Sakamoto KM, Dai W.
    Oncogene; 2000 Sep 21; 19(40):4557-62. PubMed ID: 11030144
    [Abstract] [Full Text] [Related]

  • 6. STI-571 (imatinib mesylate) enhances the apoptotic efficacy of pyrrolo-1,5-benzoxazepine-6, a novel microtubule-targeting agent, in both STI-571-sensitive and -resistant Bcr-Abl-positive human chronic myeloid leukemia cells.
    Greene LM, Kelly L, Onnis V, Campiani G, Lawler M, Williams DC, Zisterer DM.
    J Pharmacol Exp Ther; 2007 Apr 21; 321(1):288-97. PubMed ID: 17202400
    [Abstract] [Full Text] [Related]

  • 7. Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells.
    Nathwani SM, Cloonan SM, Stronach M, Campiani G, Lawler M, Williams DC, Zisterer DM.
    Oncol Rep; 2010 Dec 21; 24(6):1499-507. PubMed ID: 21042745
    [Abstract] [Full Text] [Related]

  • 8. Weakened spindle checkpoint with reduced BubR1 expression in paclitaxel-resistant ovarian carcinoma cell line SKOV3-TR30.
    Fu Y, Ye D, Chen H, Lu W, Ye F, Xie X.
    Gynecol Oncol; 2007 Apr 21; 105(1):66-73. PubMed ID: 17234259
    [Abstract] [Full Text] [Related]

  • 9. Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1.
    Gupta A, Inaba S, Wong OK, Fang G, Liu J.
    Oncogene; 2003 Oct 23; 22(48):7593-9. PubMed ID: 14576821
    [Abstract] [Full Text] [Related]

  • 10. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT.
    Carcinogenesis; 2013 Aug 23; 34(8):1852-60. PubMed ID: 23615402
    [Abstract] [Full Text] [Related]

  • 11. Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents.
    Zisterer DM, Campiani G, Nacci V, Williams DC.
    J Pharmacol Exp Ther; 2000 Apr 23; 293(1):48-59. PubMed ID: 10734152
    [Abstract] [Full Text] [Related]

  • 12. The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia.
    McElligott AM, Maginn EN, Greene LM, McGuckin S, Hayat A, Browne PV, Butini S, Campiani G, Catherwood MA, Vandenberghe E, Williams DC, Zisterer DM, Lawler M.
    Cancer Res; 2009 Nov 01; 69(21):8366-75. PubMed ID: 19826055
    [Abstract] [Full Text] [Related]

  • 13. BUBR1 phosphorylation is regulated during mitotic checkpoint activation.
    Li W, Lan Z, Wu H, Wu S, Meadows J, Chen J, Zhu V, Dai W.
    Cell Growth Differ; 1999 Nov 01; 10(11):769-75. PubMed ID: 10593653
    [Abstract] [Full Text] [Related]

  • 14. Induction of centrosome amplification during arsenite-induced mitotic arrest in CGL-2 cells.
    Yih LH, Tseng YY, Wu YC, Lee TC.
    Cancer Res; 2006 Feb 15; 66(4):2098-106. PubMed ID: 16489010
    [Abstract] [Full Text] [Related]

  • 15. Chromosome damage in mitosis induces BubR1 activation and prometaphase arrest.
    Choi E, Lee H.
    FEBS Lett; 2008 May 28; 582(12):1700-6. PubMed ID: 18440313
    [Abstract] [Full Text] [Related]

  • 16. The mitotic checkpoint gene BubR1 has two distinct functions in mitosis.
    Harris L, Davenport J, Neale G, Goorha R.
    Exp Cell Res; 2005 Aug 01; 308(1):85-100. PubMed ID: 15907836
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
    Vogel C, Hager C, Bastians H.
    Cancer Res; 2007 Jan 01; 67(1):339-45. PubMed ID: 17210716
    [Abstract] [Full Text] [Related]

  • 18. BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells.
    Greene LM, Carr M, Keeley NO, Lawler M, Meegan MJ, Zisterer DM.
    Int J Mol Med; 2011 May 01; 27(5):715-23. PubMed ID: 21369694
    [Abstract] [Full Text] [Related]

  • 19. Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.
    Yuan B, Xu Y, Woo JH, Wang Y, Bae YK, Yoon DS, Wersto RP, Tully E, Wilsbach K, Gabrielson E.
    Clin Cancer Res; 2006 Jan 15; 12(2):405-10. PubMed ID: 16428479
    [Abstract] [Full Text] [Related]

  • 20. Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.
    Grabsch H, Takeno S, Parsons WJ, Pomjanski N, Boecking A, Gabbert HE, Mueller W.
    J Pathol; 2003 May 15; 200(1):16-22. PubMed ID: 12692836
    [Abstract] [Full Text] [Related]

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