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280 related items for PubMed ID: 17993254

  • 1. Assessment of the genotoxicity of the rat carcinogen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in rat liver epithelial cells in vitro.
    Mäki-Paakkanen J, Hakulinen P.
    Toxicol In Vitro; 2008 Mar; 22(2):535-40. PubMed ID: 17993254
    [Abstract] [Full Text] [Related]

  • 2. MX, a by-product of water chlorination, lacks in vivo genotoxicity in gpt delta mice but inhibits gap junctional intercellular communication in rat WB cells.
    Nishikawa A, Sai K, Okazaki K, Son HY, Kanki K, Nakajima M, Kinae N, Nohmi T, Trosko JE, Inoue T, Hirose M.
    Environ Mol Mutagen; 2006 Jan; 47(1):48-55. PubMed ID: 16106442
    [Abstract] [Full Text] [Related]

  • 3. Induction of TK mutations in human lymphoblastoid TK6 cells by the rat carcinogen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
    Hakulinen P, Yamamoto A, Koyama N, Kumita W, Yasui M, Honma M.
    Mutat Res; 2011 Oct 09; 725(1-2):43-9. PubMed ID: 21784170
    [Abstract] [Full Text] [Related]

  • 4. Potent inhibition of gap junctional intercellular communication by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in BALB/c 3T3 cells.
    Hakulinen P, Mäki-Paakkanen J, Naarala J, Kronberg L, Komulainen H.
    Toxicol Lett; 2004 Aug 01; 151(3):439-49. PubMed ID: 15261988
    [Abstract] [Full Text] [Related]

  • 5. 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) induces gene mutations and inhibits metabolic cooperation in cultured Chinese hamster cells.
    Matsumura H, Watanabe M, Matsumoto K, Ohta T.
    J Toxicol Environ Health; 1994 Sep 01; 43(1):65-72. PubMed ID: 8078093
    [Abstract] [Full Text] [Related]

  • 6. Oxidative stress and DNA damage induced by a drinking-water chlorination disinfection byproduct 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in mice.
    Yuan J, Liu H, Zhou LH, Zou YL, Lu WQ.
    Mutat Res; 2006 Oct 30; 609(2):129-36. PubMed ID: 16952480
    [Abstract] [Full Text] [Related]

  • 7. Carcinogenicity of the chlorination disinfection by-product MX.
    McDonald TA, Komulainen H.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2005 Oct 30; 23(2):163-214. PubMed ID: 16291527
    [Abstract] [Full Text] [Related]

  • 8. Promoting effects of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone on rat glandular stomach carcinogenesis initiated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Nishikawa A, Furukawa F, Lee IS, Kasahara K, Tanakamaru Z, Nakamura H, Miyauchi M, Kinae N, Hirose M.
    Cancer Res; 1999 May 01; 59(9):2045-9. PubMed ID: 10232584
    [Abstract] [Full Text] [Related]

  • 9. MX [3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone], a drinking-water carcinogen, does not induce mutations in the liver of cII transgenic medaka (Oryzias latipes).
    Geter DR, Winn RN, Fournie JW, Norris MB, DeAngelo AB, Hawkins WE.
    J Toxicol Environ Health A; 2004 Mar 12; 67(5):373-83. PubMed ID: 14718174
    [Abstract] [Full Text] [Related]

  • 10. Genotoxic effects of the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) in mammalian cells in vitro and in rats in vivo.
    Brunborg G, Holme JA, Søderlund EJ, Hongslo JK, Vartiainen T, Lötjönen S, Becher G.
    Mutat Res; 1991 May 12; 260(1):55-64. PubMed ID: 1902909
    [Abstract] [Full Text] [Related]

  • 11. Induction of gene mutation in mammalian cells by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinfection by-product in drinking water.
    Jansson K, Hyttinen JM.
    Mutat Res; 1994 Aug 12; 322(2):129-32. PubMed ID: 7519319
    [Abstract] [Full Text] [Related]

  • 12. Developmental toxicity evaluation of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in Wistar rats.
    Huuskonen H, Venäläinen R, Komulainen H.
    Birth Defects Res B Dev Reprod Toxicol; 2003 Apr 12; 68(2):172-9. PubMed ID: 12866708
    [Abstract] [Full Text] [Related]

  • 13. Bacterial and mammalian-cell genotoxicity of mixtures of chlorohydroxyfuranones, by-products of water chlorination.
    Mäki-Paakkanen J, Komulainen H, Kronberg L.
    Environ Mol Mutagen; 2004 Apr 12; 43(4):217-25. PubMed ID: 15141360
    [Abstract] [Full Text] [Related]

  • 14. 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone [MX] shows initiating and promoting activities in a two-stage BALB/c 3T3 cell transformation assay.
    Nakajima M, Shimada S, Nagai M, Mizuhashi F, Sugiyama C, Masuda S, Hayashi M, Kinae N.
    Mutagenesis; 2005 Sep 12; 20(5):375-9. PubMed ID: 16081471
    [Abstract] [Full Text] [Related]

  • 15. Effects of chlorohydroxyfuranones on 3-methylcholanthrene-induced neoplastic transformation in the two-stage transformation assay in C3H 10T1/2 cells.
    Laaksonen M, Mäki-Paakkanen J, Kronberg L, Komulainen H.
    Arch Toxicol; 2003 Oct 12; 77(10):594-600. PubMed ID: 14574448
    [Abstract] [Full Text] [Related]

  • 16. The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone(mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, balb/ca mice or C57bl/6J-min mice.
    Steffensen IL, Paulsen JE, Engeset D, Kronberg L, Alexander J.
    Pharmacol Toxicol; 1999 Aug 12; 85(2):56-64. PubMed ID: 10488686
    [Abstract] [Full Text] [Related]

  • 17. Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products.
    Plewa MJ, Kargalioglu Y, Vankerk D, Minear RA, Wagner ED.
    Environ Mol Mutagen; 2002 Aug 12; 40(2):134-42. PubMed ID: 12203407
    [Abstract] [Full Text] [Related]

  • 18. Expression of p53 and p21 Ki-ras proteins in rat thyroid gland tumors induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
    Hakulinen P, Kosma VM, Komulainen H.
    Anticancer Res; 2002 Aug 12; 22(2A):703-6. PubMed ID: 12014640
    [Abstract] [Full Text] [Related]

  • 19. Comparable DNA and chromosome damage in Chinese hamster ovary cells by chlorohydroxyfuranones.
    Mäki-Paakkanen J, Laaksonen M, Munter T, Kronberg L, Komulainen H.
    Environ Mol Mutagen; 2001 Aug 12; 38(4):297-305. PubMed ID: 11774360
    [Abstract] [Full Text] [Related]

  • 20. Mutation spectra of the drinking water mutagen 3-chloro-4-methyl-5-hydroxy-2(5H)-furanone (MCF) in Salmonella TA100 and TA104: comparison to MX.
    Shaughnessy DT, Ohe T, Landi S, Warren SH, Richard AM, Munter T, Franzén R, Kronberg L, DeMarini DM.
    Environ Mol Mutagen; 2000 Aug 12; 35(2):106-13. PubMed ID: 10712744
    [Abstract] [Full Text] [Related]

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