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Journal Abstract Search

188 related items for PubMed ID: 18000940

  • 1. Heteroaryl-substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine derivatives as potent and selective corticotropin-releasing factor receptor-1 antagonists.
    Sabbatini FM, Di Fabio R, St-Denis Y, Capelli AM, Castiglioni E, Contini S, Donati D, Fazzolari E, Gentile G, Micheli F, Pavone F, Rinaldi M, Pasquarello A, Zampori MG, Di Felice P, Zarantonello P, Arban R, Perini B, Vitulli G, Benedetti R, Oliosi B, Worby A.
    ChemMedChem; 2008 Feb; 3(2):226-9. PubMed ID: 18000940
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  • 2. Cyclopenta[d]pyrimidines and dihydropyrrolo[2,3-d]pyrimidines as potent and selective corticotropin-releasing factor 1 receptor antagonists.
    Arban R, Benedetti R, Bonanomi G, Capelli AM, Castiglioni E, Contini S, Degiorgis F, Di Felice P, Donati D, Fazzolari E, Gentile G, Marchionni C, Marchioro C, Messina F, Micheli F, Oliosi B, Pavone F, Pasquarello A, Perini B, Rinaldi M, Sabbatini FM, Vitulli G, Zarantonello P, Di Fabio R, St-Denis Y.
    ChemMedChem; 2007 Apr; 2(4):528-40. PubMed ID: 17335099
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  • 4. Optimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility.
    Chen C, Wilcoxen KM, Huang CQ, McCarthy JR, Chen T, Grigoriadis DE.
    Bioorg Med Chem Lett; 2004 Jul 16; 14(14):3669-73. PubMed ID: 15203140
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  • 6. Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists.
    Chen C, Wilcoxen KM, Huang CQ, Xie YF, McCarthy JR, Webb TR, Zhu YF, Saunders J, Liu XJ, Chen TK, Bozigian H, Grigoriadis DE.
    J Med Chem; 2004 Sep 09; 47(19):4787-98. PubMed ID: 15341493
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  • 11. Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor(1) (CRF(1)) receptor antagonists.
    Huang CQ, Grigoriadis DE, Liu Z, McCarthy JR, Ramphal J, Webb T, Whitten JP, Xie MY, Chen C.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2083-6. PubMed ID: 15080983
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  • 13. Potential uses of corticotropin-releasing hormone antagonists.
    Zoumakis E, Rice KC, Gold PW, Chrousos GP.
    Ann N Y Acad Sci; 2006 Nov 03; 1083():239-51. PubMed ID: 17148743
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  • 14. Design and synthesis of tricyclic corticotropin-releasing factor-1 antagonists.
    Gross RS, Guo Z, Dyck B, Coon T, Huang CQ, Lowe RF, Marinkovic D, Moorjani M, Nelson J, Zamani-Kord S, Grigoriadis DE, Hoare SR, Crowe PD, Bu JH, Haddach M, McCarthy J, Saunders J, Sullivan R, Chen T, Williams JP.
    J Med Chem; 2005 Sep 08; 48(18):5780-93. PubMed ID: 16134945
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  • 16. Design, synthesis, and structure-activity relationships of novel pyrazolo[5,1-b]thiazole derivatives as potent and orally active corticotropin-releasing factor 1 receptor antagonists.
    Takahashi Y, Hashizume M, Shin K, Terauchi T, Takeda K, Hibi S, Murata-Tai K, Fujisawa M, Shikata K, Taguchi R, Ino M, Shibata H, Yonaga M.
    J Med Chem; 2012 Oct 11; 55(19):8450-63. PubMed ID: 22971011
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  • 19. Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice.
    Nielsen DM, Carey GJ, Gold LH.
    Eur J Pharmacol; 2004 Sep 19; 499(1-2):135-46. PubMed ID: 15363960
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  • 20. Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists.
    Wustrow DJ, Capiris T, Rubin R, Knobelsdorf JA, Akunne H, Davis MD, MacKenzie R, Pugsley TA, Zoski KT, Heffner TG, Wise LD.
    Bioorg Med Chem Lett; 1998 Aug 18; 8(16):2067-70. PubMed ID: 9873487
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