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1144 related items for PubMed ID: 18004725

  • 1. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S, Koistinaho M.
    Glia; 2008 Jan 15; 56(2):154-63. PubMed ID: 18004725
    [Abstract] [Full Text] [Related]

  • 2. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep 15; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 3. A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.
    Flood DG, Lin YG, Lang DM, Trusko SP, Hirsch JD, Savage MJ, Scott RW, Howland DS.
    Neurobiol Aging; 2009 Jul 15; 30(7):1078-90. PubMed ID: 18053619
    [Abstract] [Full Text] [Related]

  • 4. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.
    Malm TM, Koistinaho M, Pärepalo M, Vatanen T, Ooka A, Karlsson S, Koistinaho J.
    Neurobiol Dis; 2005 Feb 15; 18(1):134-42. PubMed ID: 15649704
    [Abstract] [Full Text] [Related]

  • 5. In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
    Härtig W, Kacza J, Paulke BR, Grosche J, Bauer U, Hoffmann A, Elsinghorst PW, Gütschow M.
    Eur J Neurosci; 2010 Jan 15; 31(1):99-109. PubMed ID: 20092557
    [Abstract] [Full Text] [Related]

  • 6. High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
    Güntert A, Döbeli H, Bohrmann B.
    Neuroscience; 2006 Dec 01; 143(2):461-75. PubMed ID: 17008022
    [Abstract] [Full Text] [Related]

  • 7. Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice.
    Zhang X, Luhrs KJ, Ryff KA, Malik WT, Driscoll MJ, Culver B.
    Neuroscience; 2009 Jun 16; 161(1):53-8. PubMed ID: 19286451
    [Abstract] [Full Text] [Related]

  • 8. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
    Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR.
    Neurobiol Dis; 2005 Apr 16; 18(3):602-17. PubMed ID: 15755686
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics and amyloid plaque targeting ability of a novel peptide-based magnetic resonance contrast agent in wild-type and Alzheimer's disease transgenic mice.
    Kandimalla KK, Wengenack TM, Curran GL, Gilles EJ, Poduslo JF.
    J Pharmacol Exp Ther; 2007 Aug 16; 322(2):541-9. PubMed ID: 17505020
    [Abstract] [Full Text] [Related]

  • 10. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
    Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR.
    Exp Neurol; 2001 Sep 16; 171(1):59-71. PubMed ID: 11520121
    [Abstract] [Full Text] [Related]

  • 11. Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.
    Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, Kitamoto T.
    Acta Neuropathol; 2007 Jun 16; 113(6):627-36. PubMed ID: 17431643
    [Abstract] [Full Text] [Related]

  • 12. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease.
    Simard AR, Soulet D, Gowing G, Julien JP, Rivest S.
    Neuron; 2006 Feb 16; 49(4):489-502. PubMed ID: 16476660
    [Abstract] [Full Text] [Related]

  • 13. Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.
    Koistinaho M, Lin S, Wu X, Esterman M, Koger D, Hanson J, Higgs R, Liu F, Malkani S, Bales KR, Paul SM.
    Nat Med; 2004 Jul 16; 10(7):719-26. PubMed ID: 15195085
    [Abstract] [Full Text] [Related]

  • 14. Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.
    Hartlage-Rübsamen M, Zeitschel U, Apelt J, Gärtner U, Franke H, Stahl T, Günther A, Schliebs R, Penkowa M, Bigl V, Rossner S.
    Glia; 2003 Jan 15; 41(2):169-79. PubMed ID: 12509807
    [Abstract] [Full Text] [Related]

  • 15. Indirubin-3'-monoxime rescues spatial memory deficits and attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimer's disease.
    Ding Y, Qiao A, Fan GH.
    Neurobiol Dis; 2010 Aug 15; 39(2):156-68. PubMed ID: 20381617
    [Abstract] [Full Text] [Related]

  • 16. Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
    Melnikova T, Savonenko A, Wang Q, Liang X, Hand T, Wu L, Kaufmann WE, Vehmas A, Andreasson KI.
    Neuroscience; 2006 Sep 01; 141(3):1149-62. PubMed ID: 16753269
    [Abstract] [Full Text] [Related]

  • 17. Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.
    Van Broeck B, Vanhoutte G, Pirici D, Van Dam D, Wils H, Cuijt I, Vennekens K, Zabielski M, Michalik A, Theuns J, De Deyn PP, Van der Linden A, Van Broeckhoven C, Kumar-Singh S.
    Neurobiol Aging; 2008 Feb 01; 29(2):241-52. PubMed ID: 17112635
    [Abstract] [Full Text] [Related]

  • 18. Adult mouse astrocytes degrade amyloid-beta in vitro and in situ.
    Wyss-Coray T, Loike JD, Brionne TC, Lu E, Anankov R, Yan F, Silverstein SC, Husemann J.
    Nat Med; 2003 Apr 01; 9(4):453-7. PubMed ID: 12612547
    [Abstract] [Full Text] [Related]

  • 19. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.
    Behav Brain Res; 2011 Sep 23; 222(2):342-50. PubMed ID: 21513747
    [Abstract] [Full Text] [Related]

  • 20. Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
    Howlett DR, Richardson JC, Austin A, Parsons AA, Bate ST, Davies DC, Gonzalez MI.
    Brain Res; 2004 Aug 13; 1017(1-2):130-6. PubMed ID: 15261108
    [Abstract] [Full Text] [Related]


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