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Journal Abstract Search

336 related items for PubMed ID: 18004886

  • 1. Interactions of substrates at the surface of P450s can greatly enhance substrate potency.
    Hegde A, Haines DC, Bondlela M, Chen B, Schaffer N, Tomchick DR, Machius M, Nguyen H, Chowdhary PK, Stewart L, Lopez C, Peterson JA.
    Biochemistry; 2007 Dec 11; 46(49):14010-7. PubMed ID: 18004886
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
    Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, Peterson JA.
    Biochemistry; 2008 Mar 25; 47(12):3662-70. PubMed ID: 18298086
    [Abstract] [Full Text] [Related]

  • 3. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
    Gustafsson MC, Roitel O, Marshall KR, Noble MA, Chapman SK, Pessegueiro A, Fulco AJ, Cheesman MR, von Wachenfeldt C, Munro AW.
    Biochemistry; 2004 May 11; 43(18):5474-87. PubMed ID: 15122913
    [Abstract] [Full Text] [Related]

  • 4. P450BM-3: absolute configuration of the primary metabolites of palmitic acid.
    Truan G, Komandla MR, Falck JR, Peterson JA.
    Arch Biochem Biophys; 1999 Jun 15; 366(2):192-8. PubMed ID: 10356283
    [Abstract] [Full Text] [Related]

  • 5. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
    Huang WC, Westlake AC, Maréchal JD, Joyce MG, Moody PC, Roberts GC.
    J Mol Biol; 2007 Oct 26; 373(3):633-51. PubMed ID: 17868686
    [Abstract] [Full Text] [Related]

  • 6. Obligatory intermolecular electron-transfer from FAD to FMN in dimeric P450BM-3.
    Kitazume T, Haines DC, Estabrook RW, Chen B, Peterson JA.
    Biochemistry; 2007 Oct 23; 46(42):11892-901. PubMed ID: 17902705
    [Abstract] [Full Text] [Related]

  • 7. How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.
    Lüdemann SK, Lounnas V, Wade RC.
    J Mol Biol; 2000 Nov 10; 303(5):797-811. PubMed ID: 11061976
    [Abstract] [Full Text] [Related]

  • 8. Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.
    Li QS, Ogawa J, Shimizu S.
    Biochem Biophys Res Commun; 2001 Feb 09; 280(5):1258-61. PubMed ID: 11162663
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  • 11. Thr268 in substrate binding and catalysis in P450BM-3.
    Truan G, Peterson JA.
    Arch Biochem Biophys; 1998 Jan 01; 349(1):53-64. PubMed ID: 9439582
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  • 13. P450BM-3; a tale of two domains--or is it three?
    Peterson JA, Sevrioukova I, Truan G, Graham-Lorence SE.
    Steroids; 1997 Jan 01; 62(1):117-23. PubMed ID: 9029725
    [Abstract] [Full Text] [Related]

  • 14. Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains.
    Sevrioukova I, Truan G, Peterson JA.
    Arch Biochem Biophys; 1997 Apr 15; 340(2):231-8. PubMed ID: 9143326
    [Abstract] [Full Text] [Related]

  • 15. The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid.
    Li H, Poulos TL.
    Nat Struct Biol; 1997 Feb 15; 4(2):140-6. PubMed ID: 9033595
    [Abstract] [Full Text] [Related]

  • 16. A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, P450 102, and P450 108.
    de Groot MJ, Vermeulen NP, Kramer JD, van Acker FA, Donné-Op den Kelder GM.
    Chem Res Toxicol; 1996 Feb 15; 9(7):1079-91. PubMed ID: 8902262
    [Abstract] [Full Text] [Related]

  • 17. Dithionite-supported hydroxylation of palmitic acid by cytochrome P450BM-3.
    Fang X, Halpert JR.
    Drug Metab Dispos; 1996 Nov 15; 24(11):1282-5. PubMed ID: 8937865
    [Abstract] [Full Text] [Related]

  • 18. Molecular dynamics simulations of P450 BM3--examination of substrate-induced conformational change.
    Chang YT, Loew GH.
    J Biomol Struct Dyn; 1999 Jun 15; 16(6):1189-203. PubMed ID: 10447203
    [Abstract] [Full Text] [Related]

  • 19. Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes.
    Shimada T, Mernaugh RL, Guengerich FP.
    Arch Biochem Biophys; 2005 Mar 01; 435(1):207-16. PubMed ID: 15680923
    [Abstract] [Full Text] [Related]

  • 20. Thermal equilibrium of high- and low-spin forms of cytochrome P450 BM-3: repositioning of the substrate?
    Jovanovic T, Farid R, Friesner RA, McDermott AE.
    J Am Chem Soc; 2005 Oct 05; 127(39):13548-52. PubMed ID: 16190718
    [Abstract] [Full Text] [Related]

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