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PUBMED FOR HANDHELDS

Journal Abstract Search

146 related items for PubMed ID: 18007417

  • 1. Unexpected syntheses of seco-cyclopropyltetrahydroquinolines - from a radical 5-exo-trig cyclization reaction: analogs of CC-1065 and the duocarmycins.
    Pati H, Howard T, Townes H, Lingerfelt B, McNulty L, Lee M.
    Molecules; 2004 Feb 28; 9(3):125-33. PubMed ID: 18007417
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  • 2. Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
    Howard TT, Lingerfelt BM, Purnell BL, Scott AE, Price CA, Townes HM, McNulty L, Handl HL, Summerville K, Hudson SJ, Bowen JP, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2002 Sep 28; 10(9):2941-52. PubMed ID: 12110316
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  • 3. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents.
    Patil PC, Satam V, Lee M.
    Anticancer Agents Med Chem; 2015 Sep 28; 15(5):616-30. PubMed ID: 25511515
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  • 4. Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems.
    Twum EA, Nathubhai A, Wood PJ, Lloyd MD, Thompson AS, Threadgill MD.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3481-9. PubMed ID: 25963825
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  • 5. A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
    Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2004 Dec 01; 12(23):6221-36. PubMed ID: 15519165
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  • 6. A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
    Sato A, McNulty L, Cox K, Kim S, Scott A, Daniell K, Summerville K, Price C, Hudson S, Kiakos K, Hartley JA, Asao T, Lee M.
    J Med Chem; 2005 Jun 02; 48(11):3903-18. PubMed ID: 15916443
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  • 9. Asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).
    Lajiness JP, Boger DL.
    J Org Chem; 2011 Jan 21; 76(2):583-7. PubMed ID: 21192653
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  • 12. DNA interstrand crosslinking agents: synthesis, DNA interactions, and cytotoxicity of dimeric achiral seco-amino-CBI and conjugates of achiral seco-amino-CBI with pyrrolobenzodiazepine (PBD).
    Purnell B, Sato A, O'kelley A, Price C, Summerville K, Hudson S, O'hare C, Kiakos K, Asao T, Lee M, Hartley JA.
    Bioorg Med Chem Lett; 2006 Nov 01; 16(21):5677-81. PubMed ID: 16919946
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  • 13. Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation.
    Lajiness JP, Robertson WM, Dunwiddie I, Broward MA, Vielhauer GA, Weir SJ, Boger DL.
    J Med Chem; 2010 Nov 11; 53(21):7731-8. PubMed ID: 20942408
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  • 16. Sequence-specific alkylation by a tandem motif of pyrrole-imidazole CBI conjugate.
    Sasaki S, Minoshima M, Fujimoto J, Shinohara K, Bando T, Sugiyama H.
    Nucleic Acids Symp Ser (Oxf); 2007 Nov 11; (51):265-6. PubMed ID: 18029688
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  • 19. Antitumor activity of sequence-specific alkylating agents: pyrolle-imidazole CBI conjugates with indole linker.
    Shinohara K, Bando T, Sasaki S, Sakakibara Y, Minoshima M, Sugiyama H.
    Cancer Sci; 2006 Mar 11; 97(3):219-25. PubMed ID: 16542219
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