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204 related items for PubMed ID: 18031609

  • 1. Astragalus polysaccharide reduces hepatic endoplasmic reticulum stress and restores glucose homeostasis in a diabetic KKAy mouse model.
    Mao XQ, Wu Y, Wu K, Liu M, Zhang JF, Zou F, Ou-Yang JP.
    Acta Pharmacol Sin; 2007 Dec; 28(12):1947-56. PubMed ID: 18031609
    [Abstract] [Full Text] [Related]

  • 2. Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes.
    Wang N, Zhang D, Mao X, Zou F, Jin H, Ouyang J.
    Mol Cell Endocrinol; 2009 Aug 13; 307(1-2):89-98. PubMed ID: 19524131
    [Abstract] [Full Text] [Related]

  • 3. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism.
    Mao XQ, Yu F, Wang N, Wu Y, Zou F, Wu K, Liu M, Ouyang JP.
    Phytomedicine; 2009 May 13; 16(5):416-25. PubMed ID: 19201177
    [Abstract] [Full Text] [Related]

  • 4. Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B.
    Wu Y, Ou-Yang JP, Wu K, Wang Y, Zhou YF, Wen CY.
    Acta Pharmacol Sin; 2005 Mar 13; 26(3):345-52. PubMed ID: 15715932
    [Abstract] [Full Text] [Related]

  • 5. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle.
    Liu M, Wu K, Mao X, Wu Y, Ouyang J.
    J Ethnopharmacol; 2010 Jan 08; 127(1):32-7. PubMed ID: 19800959
    [Abstract] [Full Text] [Related]

  • 6. Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.
    Latreille M, Laberge MK, Bourret G, Yamani L, Larose L.
    Am J Physiol Endocrinol Metab; 2011 Mar 08; 300(3):E423-34. PubMed ID: 20587749
    [Abstract] [Full Text] [Related]

  • 7. The role of quantitative changes in the epxression of insulin receptor substrate-1 and nuclear ubiquitin in abnormal glycometabolism in the livers of KKay mice and the relative therapeutic mechanisms of Astragalus polysaccharide.
    Ye Y, Deng T, Wan XY, Ouyang JP, Liu M, Mao XQ.
    Int J Mol Med; 2014 Feb 08; 33(2):341-50. PubMed ID: 24337258
    [Abstract] [Full Text] [Related]

  • 8. Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK.
    Zou F, Mao XQ, Wang N, Liu J, Ou-Yang JP.
    Acta Pharmacol Sin; 2009 Dec 08; 30(12):1607-15. PubMed ID: 19960007
    [Abstract] [Full Text] [Related]

  • 9. Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content.
    Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.
    J Agric Food Chem; 2008 Jun 25; 56(12):4377-85. PubMed ID: 18522411
    [Abstract] [Full Text] [Related]

  • 10. Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy mouse.
    Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.
    Diabetes Obes Metab; 2008 Sep 25; 10(10):939-49. PubMed ID: 18201205
    [Abstract] [Full Text] [Related]

  • 11. Low molecular weight fucoidan improves endoplasmic reticulum stress-reduced insulin sensitivity through AMP-activated protein kinase activation in L6 myotubes and restores lipid homeostasis in a mouse model of type 2 diabetes.
    Jeong YT, Kim YD, Jung YM, Park DC, Lee DS, Ku SK, Li X, Lu Y, Chao GH, Kim KJ, Lee JY, Baek MC, Kang W, Hwang SL, Chang HW.
    Mol Pharmacol; 2013 Jul 25; 84(1):147-57. PubMed ID: 23658008
    [Abstract] [Full Text] [Related]

  • 12. Rhaponticin from rhubarb rhizomes alleviates liver steatosis and improves blood glucose and lipid profiles in KK/Ay diabetic mice.
    Chen J, Ma M, Lu Y, Wang L, Wu C, Duan H.
    Planta Med; 2009 Apr 25; 75(5):472-7. PubMed ID: 19235684
    [Abstract] [Full Text] [Related]

  • 13. Acute exercise reduces insulin resistance-induced TRB3 expression and amelioration of the hepatic production of glucose in the liver of diabetic mice.
    Lima AF, Ropelle ER, Pauli JR, Cintra DE, Frederico MJ, Pinho RA, Velloso LA, De Souza CT.
    J Cell Physiol; 2009 Oct 25; 221(1):92-7. PubMed ID: 19492410
    [Abstract] [Full Text] [Related]

  • 14. Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
    Han KL, Choi JS, Lee JY, Song J, Joe MK, Jung MH, Hwang JK.
    Diabetes; 2008 Mar 25; 57(3):737-45. PubMed ID: 18065517
    [Abstract] [Full Text] [Related]

  • 15. Liraglutide ameliorates glycometabolism and insulin resistance through the upregulation of GLUT4 in diabetic KKAy mice.
    Chen LN, Lyu J, Yang XF, Ji WJ, Yuan BX, Chen MX, Ma X, Wang B.
    Int J Mol Med; 2013 Oct 25; 32(4):892-900. PubMed ID: 23877319
    [Abstract] [Full Text] [Related]

  • 16. Merit of Astragalus polysaccharide in the improvement of early diabetic nephropathy with an effect on mRNA expressions of NF-kappaB and IkappaB in renal cortex of streptozotoxin-induced diabetic rats.
    Zhang YW, Wu CY, Cheng JT.
    J Ethnopharmacol; 2007 Dec 03; 114(3):387-92. PubMed ID: 17900838
    [Abstract] [Full Text] [Related]

  • 17. Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis.
    Lee YS, Shin S, Shigihara T, Hahm E, Liu MJ, Han J, Yoon JW, Jun HS.
    Diabetes; 2007 Jun 03; 56(6):1671-9. PubMed ID: 17369525
    [Abstract] [Full Text] [Related]

  • 18. Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model.
    Novelli M, D'Aleo V, Lupi R, Paolini M, Soleti A, Marchetti P, Masiello P.
    Pancreas; 2007 Nov 03; 35(4):e10-7. PubMed ID: 18090226
    [Abstract] [Full Text] [Related]

  • 19. APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
    Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y.
    J Mol Endocrinol; 2019 Jul 03; 63(1):77-91. PubMed ID: 31137008
    [Abstract] [Full Text] [Related]

  • 20. Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function.
    Matsuda T, Kido Y, Uchida T, Kasuga M.
    Kobe J Med Sci; 2008 Jul 18; 54(2):E114-21. PubMed ID: 18772613
    [Abstract] [Full Text] [Related]

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