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2. Pressure and temperature jump relaxation kinetics of the conformational change in Salmonella typhimurium tryptophan synthase L-serine complex: large activation compressibility and heat capacity changes demonstrate the contribution of solvation. Phillips RS, Miles EW, McPhie P, Marchal S, Georges C, Dupont Y, Lange R. J Am Chem Soc; 2008 Oct 15; 130(41):13580-8. PubMed ID: 18795779 [Abstract] [Full Text] [Related]
3. Hydrostatic pressure affects the conformational equilibrium of Salmonella typhimurium tryptophan synthase. Phillips RS, Miles EW, Holtermann G, Goody RS. Biochemistry; 2005 May 31; 44(21):7921-8. PubMed ID: 15910007 [Abstract] [Full Text] [Related]
6. Tryptophan synthase: structure and function of the monovalent cation site. Dierkers AT, Niks D, Schlichting I, Dunn MF. Biochemistry; 2009 Nov 24; 48(46):10997-1010. PubMed ID: 19848417 [Abstract] [Full Text] [Related]
7. Effects of hydrostatic pressure on the conformational equilibrium of tryptophan synthase from Salmonella typhimurium. Phillips RS, Miles EW, McPhie P, Marchal S, Lange R, Holtermann G, Goody RS. Ann N Y Acad Sci; 2010 Feb 24; 1189():95-103. PubMed ID: 20233374 [Abstract] [Full Text] [Related]
8. Structural Basis of the Stereochemistry of Inhibition of Tryptophan Synthase by Tryptophan and Derivatives. Phillips RS, Harris AP. Biochemistry; 2021 Jan 26; 60(3):231-244. PubMed ID: 33428374 [Abstract] [Full Text] [Related]
9. Detection of open and closed conformations of tryptophan synthase by 15N-heteronuclear single-quantum coherence nuclear magnetic resonance of bound 1-15N-L-tryptophan. Osborne A, Teng Q, Miles EW, Phillips RS. J Biol Chem; 2003 Nov 07; 278(45):44083-90. PubMed ID: 12939261 [Abstract] [Full Text] [Related]
10. Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity. Ferrari D, Yang LH, Miles EW, Dunn MF. Biochemistry; 2001 Jun 26; 40(25):7421-32. PubMed ID: 11412095 [Abstract] [Full Text] [Related]
11. Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands. Ngo H, Kimmich N, Harris R, Niks D, Blumenstein L, Kulik V, Barends TR, Schlichting I, Dunn MF. Biochemistry; 2007 Jul 03; 46(26):7740-53. PubMed ID: 17559232 [Abstract] [Full Text] [Related]
12. beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex. Pan P, Dunn MF. Biochemistry; 1996 Apr 16; 35(15):5002-13. PubMed ID: 8664293 [Abstract] [Full Text] [Related]
13. Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha 2 beta 2 complex. Peracchi A, Mozzarelli A, Rossi GL. Biochemistry; 1995 Jul 25; 34(29):9459-65. PubMed ID: 7626616 [Abstract] [Full Text] [Related]
14. Allosteric regulation of tryptophan synthase: effects of pH, temperature, and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate-L-serine intermediates. Peracchi A, Bettati S, Mozzarelli A, Rossi GL, Miles EW, Dunn MF. Biochemistry; 1996 Feb 13; 35(6):1872-80. PubMed ID: 8639669 [Abstract] [Full Text] [Related]
15. Time-resolved fluorescence of tryptophan synthase. Vaccari S, Benci S, Peracchi A, Mozzarelli A. Biophys Chem; 1996 Aug 30; 61(1):9-22. PubMed ID: 8855356 [Abstract] [Full Text] [Related]
16. Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium. Raboni S, Mozzarelli A, Cook PF. Biochemistry; 2007 Nov 13; 46(45):13223-34. PubMed ID: 17927213 [Abstract] [Full Text] [Related]
17. Allosteric linkages between beta-site covalent transformations and alpha-site activation and deactivation in the tryptophan synthase bienzyme complex. Leja CA, Woehl EU, Dunn MF. Biochemistry; 1995 May 16; 34(19):6552-61. PubMed ID: 7756286 [Abstract] [Full Text] [Related]
18. BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase. Blumenstein L, Domratcheva T, Niks D, Ngo H, Seidel R, Dunn MF, Schlichting I. Biochemistry; 2007 Dec 11; 46(49):14100-16. PubMed ID: 18004874 [Abstract] [Full Text] [Related]
19. Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding. Casino P, Niks D, Ngo H, Pan P, Brzovic P, Blumenstein L, Barends TR, Schlichting I, Dunn MF. Biochemistry; 2007 Jul 03; 46(26):7728-39. PubMed ID: 17559231 [Abstract] [Full Text] [Related]
20. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes. Rhee S, Parris KD, Hyde CC, Ahmed SA, Miles EW, Davies DR. Biochemistry; 1997 Jun 24; 36(25):7664-80. PubMed ID: 9201907 [Abstract] [Full Text] [Related] Page: [Next] [New Search]