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275 related items for PubMed ID: 18054347

  • 1. Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.
    Hira A, Watanabe H, Maeda Y, Yokoo K, Sanematsu E, Fujii J, Sasaki J, Hamada A, Saito H.
    Biochem Pharmacol; 2008 Feb 15; 75(4):973-80. PubMed ID: 18054347
    [Abstract] [Full Text] [Related]

  • 2. Over-expression of MDR1 in amrubicinol-resistant lung cancer cells.
    Takakuwa O, Oguri T, Ozasa H, Uemura T, Kasai D, Miyazaki M, Maeno K, Sato S.
    Cancer Chemother Pharmacol; 2011 Sep 15; 68(3):669-76. PubMed ID: 21128075
    [Abstract] [Full Text] [Related]

  • 3. Interaction of imatinib mesilate with human P-glycoprotein.
    Hamada A, Miyano H, Watanabe H, Saito H.
    J Pharmacol Exp Ther; 2003 Nov 15; 307(2):824-8. PubMed ID: 12975485
    [Abstract] [Full Text] [Related]

  • 4. Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein.
    Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJ.
    J Pharmacol Exp Ther; 2004 Sep 15; 310(3):1199-207. PubMed ID: 15100388
    [Abstract] [Full Text] [Related]

  • 5. Transport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1.
    Ito T, Yano I, Tanaka K, Inui KI.
    J Pharmacol Exp Ther; 1997 Aug 15; 282(2):955-60. PubMed ID: 9262363
    [Abstract] [Full Text] [Related]

  • 6. Evidence for the involvement of P-glycoprotein on the extrusion of taken up L-DOPA in cyclosporine A treated LLC-PK1 cells.
    Soares-da-Silva P, Serrão MP, Vieira-Coelho MA, Pestana M.
    Br J Pharmacol; 1998 Jan 15; 123(1):13-22. PubMed ID: 9484849
    [Abstract] [Full Text] [Related]

  • 7. Increased cellular accumulation and distribution of amrubicin contribute to its activity in anthracycline-resistant cancer cells.
    Mamidipudi V, Shi T, Brady H, Surapaneni S, Chopra R, Aukerman SL, Heise C, Sung V.
    Cancer Chemother Pharmacol; 2012 Apr 15; 69(4):965-76. PubMed ID: 22120960
    [Abstract] [Full Text] [Related]

  • 8. Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines.
    Kühne A, Tzvetkov MV, Hagos Y, Lage H, Burckhardt G, Brockmöller J.
    Biochem Pharmacol; 2009 Jul 01; 78(1):45-53. PubMed ID: 19447222
    [Abstract] [Full Text] [Related]

  • 9. Additive effects of amrubicin with cisplatin on human lung cancer cell lines.
    Yamauchi S, Kudoh S, Kimura T, Hirata K, Yoshikawa J.
    Osaka City Med J; 2002 Jun 01; 48(1):69-76. PubMed ID: 12375699
    [Abstract] [Full Text] [Related]

  • 10. Cytotoxicity of amrubicin, a novel 9-aminoanthracycline, and its active metabolite amrubicinol on human tumor cells.
    Yamaoka T, Hanada M, Ichii S, Morisada S, Noguchi T, Yanagi Y.
    Jpn J Cancer Res; 1998 Oct 01; 89(10):1067-73. PubMed ID: 9849587
    [Abstract] [Full Text] [Related]

  • 11. Modification of thermosensitivity by amrubicin or amrubicinol in human lung adenocarcinoma A549 cells and the kinetics of apoptosis and necrosis induction.
    Hayashi S, Hatashita M, Matsumoto H, Jin ZH, Shioura H, Kano E.
    Int J Mol Med; 2005 Sep 01; 16(3):381-7. PubMed ID: 16077943
    [Abstract] [Full Text] [Related]

  • 12. Role of P-glycoprotein in the efflux of raltegravir from human intestinal cells and CD4+ T-cells as an interaction target for anti-HIV agents.
    Hashiguchi Y, Hamada A, Shinohara T, Tsuchiya K, Jono H, Saito H.
    Biochem Biophys Res Commun; 2013 Sep 20; 439(2):221-7. PubMed ID: 23981805
    [Abstract] [Full Text] [Related]

  • 13. Modulation of cellular cholesterol alters P-glycoprotein activity in multidrug-resistant cells.
    Troost J, Lindenmaier H, Haefeli WE, Weiss J.
    Mol Pharmacol; 2004 Nov 20; 66(5):1332-9. PubMed ID: 15308763
    [Abstract] [Full Text] [Related]

  • 14. Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.
    Inoue T, Osada K, Tagawa M, Ogawa Y, Haga T, Sogame Y, Hashizume T, Watanabe T, Taguchi A, Katsumata T, Yabuki M, Yamaguchi N.
    Prog Neuropsychopharmacol Biol Psychiatry; 2012 Oct 01; 39(1):156-62. PubMed ID: 22691713
    [Abstract] [Full Text] [Related]

  • 15. Enhancement of radiosensitivity by topoisomerase II inhibitor, amrubicin and amrubicinol, in human lung adenocarcinoma A549 cells and kinetics of apoptosis and necrosis induction.
    Hayashi S, Hatashita M, Matsumoto H, Shioura H, Kitai R, Kano E.
    Int J Mol Med; 2006 Nov 01; 18(5):909-15. PubMed ID: 17016621
    [Abstract] [Full Text] [Related]

  • 16. Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies.
    Batrakova EV, Miller DW, Li S, Alakhov VY, Kabanov AV, Elmquist WF.
    J Pharmacol Exp Ther; 2001 Feb 01; 296(2):551-7. PubMed ID: 11160643
    [Abstract] [Full Text] [Related]

  • 17. Outward transfer of dopamine precursor L-3,4-dihydroxyphenylalanine (L-dopa) by native and human P-glycoprotein in LLC-PK(1) and LLC-GA5 col300 renal cells.
    Soares-Da-Silva P, Serrão MP.
    J Pharmacol Exp Ther; 2000 May 01; 293(2):697-704. PubMed ID: 10773046
    [Abstract] [Full Text] [Related]

  • 18. Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
    Tanigawara Y, Okamura N, Hirai M, Yasuhara M, Ueda K, Kioka N, Komano T, Hori R.
    J Pharmacol Exp Ther; 1992 Nov 01; 263(2):840-5. PubMed ID: 1359120
    [Abstract] [Full Text] [Related]

  • 19. Heterologous expression of various P-glycoproteins in polarized epithelial cells induces directional transport of small (type 1) and bulky (type 2) cationic drugs.
    Smit JW, Weert B, Schinkel AH, Meijer DK.
    J Pharmacol Exp Ther; 1998 Jul 01; 286(1):321-7. PubMed ID: 9655875
    [Abstract] [Full Text] [Related]

  • 20. Effects of P-glycoprotein inhibitors on transepithelial transport of cadmium in cultured renal epithelial cells, LLC-PK1 and LLC-GA5-COL 150.
    Kimura O, Endo T, Hotta Y, Sakata M.
    Toxicology; 2005 Mar 01; 208(1):123-32. PubMed ID: 15664439
    [Abstract] [Full Text] [Related]

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