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Journal Abstract Search


154 related items for PubMed ID: 18056193

  • 21. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
    Lim YP, Kuo SC, Lai ML, Huang JD.
    Pharmacogenet Genomics; 2009 Jan; 19(1):11-24. PubMed ID: 19077665
    [Abstract] [Full Text] [Related]

  • 22. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.
    Drug Metab Dispos; 2007 Jan; 35(1):36-42. PubMed ID: 17020958
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  • 23. Genetic polymorphisms of CYP1A2, CYP3A4, CYP3A5, pregnane/steroid X receptor and constitutive androstane receptor in 207 healthy Spanish volunteers.
    Oliver P, Lubomirov R, Carcas A.
    Clin Chem Lab Med; 2010 May; 48(5):635-9. PubMed ID: 20218903
    [Abstract] [Full Text] [Related]

  • 24. Expression of constitutive androstane receptor, hepatic nuclear factor 4 alpha, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver.
    Wortham M, Czerwinski M, He L, Parkinson A, Wan YJ.
    Drug Metab Dispos; 2007 Sep; 35(9):1700-10. PubMed ID: 17576804
    [Abstract] [Full Text] [Related]

  • 25. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
    [Abstract] [Full Text] [Related]

  • 26. Combined effects of hepatocyte nuclear factor 4α and constitutive androstane receptor on stable warfarin doses.
    Moon JY, Lee KE, Chang BC, Jeong E, Jeong H, Gwak HS.
    Pharmacogenet Genomics; 2015 Jan 01; 25(1):38-40. PubMed ID: 25356900
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  • 28. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.
    Arch Biochem Biophys; 1999 Aug 01; 368(1):14-22. PubMed ID: 10415106
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  • 29. Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig.
    Nannelli A, Chirulli V, Longo V, Gervasi PG.
    Toxicology; 2008 Oct 30; 252(1-3):105-12. PubMed ID: 18786598
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  • 32. A Transcriptional Regulatory Network Containing Nuclear Receptors and Long Noncoding RNAs Controls Basal and Drug-Induced Expression of Cytochrome P450s in HepaRG Cells.
    Chen L, Bao Y, Piekos SC, Zhu K, Zhang L, Zhong XB.
    Mol Pharmacol; 2018 Jul 30; 94(1):749-759. PubMed ID: 29691280
    [Abstract] [Full Text] [Related]

  • 33. Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha.
    Surapureddi S, Rana R, Reddy JK, Goldstein JA.
    Mol Pharmacol; 2008 Sep 30; 74(3):913-23. PubMed ID: 18552123
    [Abstract] [Full Text] [Related]

  • 34. A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers.
    Yong WP, Wang LZ, Tham LS, Wong CI, Lee SC, Soo R, Sukri N, Lee HS, Goh BC.
    Cancer Chemother Pharmacol; 2008 Jul 30; 62(2):243-51. PubMed ID: 17909805
    [Abstract] [Full Text] [Related]

  • 35. Expression of CYP3A23/1, CYP3A2, PXR, CAR and HNF4alpha in large-for-gestational-age neonatal rats.
    Ni S, Wang X, Wang J, Zeng S, Zhao Z.
    Pharmazie; 2009 Apr 30; 64(4):252-7. PubMed ID: 19435144
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  • 36. Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.
    Lamba J, Lamba V, Strom S, Venkataramanan R, Schuetz E.
    Drug Metab Dispos; 2008 Jan 30; 36(1):169-81. PubMed ID: 17925385
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  • 37. Dexamethasone as a probe for docetaxel clearance.
    Puisset F, Chatelut E, Dalenc F, Busi F, Cresteil T, Azéma J, Poublanc M, Hennebelle I, Lafont T, Chevreau C, Roché H.
    Cancer Chemother Pharmacol; 2004 Sep 30; 54(3):265-72. PubMed ID: 15133628
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  • 38. Activation of Pregnane X Receptor-Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo.
    Wang F, Wang H, Wu Y, Wang L, Zhang L, Ye X, Peng D, Chen W.
    Drug Metab Dispos; 2019 Aug 30; 47(8):785-793. PubMed ID: 31118196
    [Abstract] [Full Text] [Related]

  • 39. NCT01110291: induction of CYP3A activity and lowered exposure to docetaxel in patients with primary breast cancer.
    Hilli J, Sailas L, Jyrkkiö S, Pyrhönen S, Laine K.
    Cancer Chemother Pharmacol; 2011 Jun 30; 67(6):1353-62. PubMed ID: 20798939
    [Abstract] [Full Text] [Related]

  • 40. PXR pharmacogenetics: association of haplotypes with hepatic CYP3A4 and ABCB1 messenger RNA expression and doxorubicin clearance in Asian breast cancer patients.
    Sandanaraj E, Lal S, Selvarajan V, Ooi LL, Wong ZW, Wong NS, Ang PC, Lee EJ, Chowbay B.
    Clin Cancer Res; 2008 Nov 01; 14(21):7116-26. PubMed ID: 18981011
    [Abstract] [Full Text] [Related]


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