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Journal Abstract Search

323 related items for PubMed ID: 18063223

  • 1. Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.
    Li L, Zhang X, Yang D, Luo G, Chen S, Le W.
    Neurobiol Aging; 2009 Jul; 30(7):1091-8. PubMed ID: 18063223
    [Abstract] [Full Text] [Related]

  • 2. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 3. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
    [Abstract] [Full Text] [Related]

  • 4. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 01; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 5. Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice.
    Kulnane LS, Lamb BT.
    Neurobiol Dis; 2001 Dec 01; 8(6):982-92. PubMed ID: 11741394
    [Abstract] [Full Text] [Related]

  • 6. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
    Barten DM, Guss VL, Corsa JA, Loo A, Hansel SB, Zheng M, Munoz B, Srinivasan K, Wang B, Robertson BJ, Polson CT, Wang J, Roberts SB, Hendrick JP, Anderson JJ, Loy JK, Denton R, Verdoorn TA, Smith DW, Felsenstein KM.
    J Pharmacol Exp Ther; 2005 Feb 01; 312(2):635-43. PubMed ID: 15452193
    [Abstract] [Full Text] [Related]

  • 7. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB, Franko M, Banks WA, Kasinadhuni P, Farr SA, Vyas K, Choudhuri V, Morley JE.
    J Exp Biol; 2009 Feb 01; 212(Pt 4):494-8. PubMed ID: 19181896
    [Abstract] [Full Text] [Related]

  • 8. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb 01; 100(3):802-9. PubMed ID: 17156133
    [Abstract] [Full Text] [Related]

  • 9. Pharmacokinetics and amyloid plaque targeting ability of a novel peptide-based magnetic resonance contrast agent in wild-type and Alzheimer's disease transgenic mice.
    Kandimalla KK, Wengenack TM, Curran GL, Gilles EJ, Poduslo JF.
    J Pharmacol Exp Ther; 2007 Aug 01; 322(2):541-9. PubMed ID: 17505020
    [Abstract] [Full Text] [Related]

  • 10. Novel aspects of accumulation dynamics and A beta composition in transgenic models of AD.
    Lewis HD, Beher D, Smith D, Hewson L, Cookson N, Reynolds DS, Dawson GR, Jiang M, Van der Ploeg LH, Qian S, Rosahl TW, Kalaria RN, Shearman MS.
    Neurobiol Aging; 2004 Oct 01; 25(9):1175-85. PubMed ID: 15312963
    [Abstract] [Full Text] [Related]

  • 11. A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.
    Flood DG, Lin YG, Lang DM, Trusko SP, Hirsch JD, Savage MJ, Scott RW, Howland DS.
    Neurobiol Aging; 2009 Jul 01; 30(7):1078-90. PubMed ID: 18053619
    [Abstract] [Full Text] [Related]

  • 12. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
    Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR.
    Exp Neurol; 2001 Sep 01; 171(1):59-71. PubMed ID: 11520121
    [Abstract] [Full Text] [Related]

  • 13. [Advances in molecular biology and clinical study of amyloid precursor protein for Alzheimer's disease].
    Xu BG, Wu X.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Apr 01; 26(2):201-9. PubMed ID: 15171563
    [Abstract] [Full Text] [Related]

  • 14. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
    Tan J, Town T, Crawford F, Mori T, DelleDonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ.
    Nat Neurosci; 2002 Dec 01; 5(12):1288-93. PubMed ID: 12402041
    [Abstract] [Full Text] [Related]

  • 15. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Lin HC, Hsieh HM, Chen YH, Hu ML.
    Neurotoxicology; 2009 Jul 01; 30(4):622-7. PubMed ID: 19635394
    [Abstract] [Full Text] [Related]

  • 16. Enhanced accumulation of tau in doubly transgenic mice expressing mutant betaAPP and presenilin-1.
    Samura E, Shoji M, Kawarabayashi T, Sasaki A, Matsubara E, Murakami T, Wuhua X, Tamura S, Ikeda M, Ishiguro K, Saido TC, Westaway D, St George Hyslop P, Harigaya Y, Abe K.
    Brain Res; 2006 Jun 13; 1094(1):192-9. PubMed ID: 16713590
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J, Ayral E, Hernandez JF, Martinez J, Checler F.
    J Neurochem; 2009 Jul 13; 110(1):275-83. PubMed ID: 19457123
    [Abstract] [Full Text] [Related]

  • 18. A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
    Philipson O, Hammarström P, Nilsson KP, Portelius E, Olofsson T, Ingelsson M, Hyman BT, Blennow K, Lannfelt L, Kalimo H, Nilsson LN.
    Neurobiol Aging; 2009 Sep 13; 30(9):1393-405. PubMed ID: 18192084
    [Abstract] [Full Text] [Related]

  • 19. Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer's disease.
    El Tannir El Tayara N, Delatour B, Le Cudennec C, Guégan M, Volk A, Dhenain M.
    Neurobiol Dis; 2006 Apr 13; 22(1):199-208. PubMed ID: 16337798
    [Abstract] [Full Text] [Related]

  • 20. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Brijbassi S, Amtul Z, Newbigging S, Westaway D, St George-Hyslop P, Rozmahel RF.
    Neurobiol Dis; 2007 Feb 13; 25(2):291-6. PubMed ID: 17071095
    [Abstract] [Full Text] [Related]

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