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Journal Abstract Search

101 related items for PubMed ID: 18065517

  • 1. Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
    Han KL, Choi JS, Lee JY, Song J, Joe MK, Jung MH, Hwang JK.
    Diabetes; 2008 Mar; 57(3):737-45. PubMed ID: 18065517
    [Abstract] [Full Text] [Related]

  • 2. PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells.
    Ke Q, Xiao Y, Liu D, Shi C, Shen R, Qin S, Jiang L, Yang J, Zhou Y.
    Biochem Pharmacol; 2024 Apr; 222():116076. PubMed ID: 38387308
    [Abstract] [Full Text] [Related]

  • 3. PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.
    Ament Z, West JA, Stanley E, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL.
    Free Radic Biol Med; 2016 Jun; 95():357-68. PubMed ID: 26654758
    [Abstract] [Full Text] [Related]

  • 4. A chemical modification of a peroxisome proliferator-activated receptor pan agonist produced a shift to a new dual alpha/gamma partial agonist endowed with mitochondrial pyruvate carrier inhibition and antidiabetic properties.
    Laghezza A, Cerchia C, Genovese M, Montanari R, Capelli D, Wackerlig J, Simic S, Falbo E, Pecora L, Leuci R, Brunetti L, Piemontese L, Tortorella P, Biswas A, Singh RP, Tambe S, Sudeep CA, Pattnaik AK, Jayaprakash V, Paoli P, Lavecchia A, Loiodice F.
    Eur J Med Chem; 2024 Sep 05; 275():116567. PubMed ID: 38865743
    [Abstract] [Full Text] [Related]

  • 5. MASLD/MASH and type 2 diabetes: Two sides of the same coin? From single PPAR to pan-PPAR agonists.
    Cooreman MP, Vonghia L, Francque SM.
    Diabetes Res Clin Pract; 2024 Jun 05; 212():111688. PubMed ID: 38697298
    [Abstract] [Full Text] [Related]

  • 6. Transcriptomics Reveals the Mechanism of Rosa roxburghii Tratt Ellagitannin in Improving Hepatic Lipid Metabolism Disorder in db/db Mice.
    Tan Y, Tan S, Ren T, Yu L, Li P, Xie G, Chen C, Yuan M, Xu Q, Chen Z.
    Nutrients; 2023 Sep 28; 15(19):. PubMed ID: 37836471
    [Abstract] [Full Text] [Related]

  • 7. A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue.
    Sheng R, Li Y, Wu Y, Liu C, Wang W, Han X, Li Y, Lei L, Jiang X, Zhang Y, Zhang Y, Li S, Hong B, Liu C, Xu Y, Si S.
    Biomed Pharmacother; 2024 Mar 28; 172():116220. PubMed ID: 38308968
    [Abstract] [Full Text] [Related]

  • 8. Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics.
    Liu L, Ma Y, Wang RL, Xu WR, Wang SQ, Chou KC.
    Drug Des Devel Ther; 2013 Mar 28; 7():279-88. PubMed ID: 23630413
    [Abstract] [Full Text] [Related]

  • 9. Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice.
    Kim SN, Lee W, Bae GU, Kim YK.
    Biochem Biophys Res Commun; 2012 Aug 10; 424(4):675-80. PubMed ID: 22789850
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and biological evaluation of deuterated indolepropionic acid derivatives as novel long-acting pan PPARα/γ/δ agonists.
    Chen L, Chen Y, Wang B, Yang Z, Cai Z, Wang X, Sun L, Li Z, Wang G.
    Bioorg Med Chem; 2023 Dec 15; 96():117533. PubMed ID: 37976807
    [Abstract] [Full Text] [Related]

  • 11. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.
    Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS.
    Science; 2006 Aug 25; 313(5790):1137-40. PubMed ID: 16931765
    [Abstract] [Full Text] [Related]

  • 12. Therapeutic, and pharmacological prospects of nutmeg seed: A comprehensive review for novel drug potential insights.
    Al-Rawi SS, Ibrahim AH, Ahmed HJ, Khudhur ZO.
    Saudi Pharm J; 2024 Jun 25; 32(6):102067. PubMed ID: 38690209
    [Abstract] [Full Text] [Related]

  • 13. Transcriptomics Reveals the Mechanism of Rosa roxburghii Tratt Ellagitannin in Improving Hepatic Lipid Metabolism Disorder in db/db Mice.
    Tan Y, Tan S, Ren T, Yu L, Li P, Xie G, Chen C, Yuan M, Xu Q, Chen Z.
    Nutrients; 2023 Sep 28; 15(19):. PubMed ID: 37836471
    [Abstract] [Full Text] [Related]

  • 14. Activation of Insulin Signaling by Botanical Products.
    Rosenzweig T, Sampson SR.
    Int J Mol Sci; 2021 Apr 18; 22(8):. PubMed ID: 33919569
    [Abstract] [Full Text] [Related]

  • 15. Anti-Helicobacter pylori, Anti-Inflammatory, Cytotoxic, and Antioxidant Activities of Mace Extracts from Myristica fragrans.
    Suthisamphat N, Dechayont B, Phuaklee P, Prajuabjinda O, Vilaichone RK, Itharat A, Mokmued K, Prommee N.
    Evid Based Complement Alternat Med; 2020 Apr 18; 2020():7576818. PubMed ID: 32308716
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetics and Tissue Distribution of Anwuligan in Rats after Intravenous and Intragastric Administration by Liquid Chromatography-Mass Spectrometry.
    Song Y, Zhang Y, Duan XY, Cui DW, Qiu X, Bian Y, Wang KF, Feng XS.
    Molecules; 2019 Dec 20; 25(1):. PubMed ID: 31861927
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of the Anti-Diabetic Activity of Some Common Herbs and Spices: Providing New Insights with Inverse Virtual Screening.
    Pereira ASP, Banegas-Luna AJ, Peña-García J, Pérez-Sánchez H, Apostolides Z.
    Molecules; 2019 Nov 07; 24(22):. PubMed ID: 31703341
    [Abstract] [Full Text] [Related]

  • 18. High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation.
    Wang YM, Liu HX, Fang NY.
    Front Pharmacol; 2018 Nov 07; 9():1491. PubMed ID: 30666198
    [Abstract] [Full Text] [Related]

  • 19. New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis.
    Yuan T, Yang T, Chen H, Fu D, Hu Y, Wang J, Yuan Q, Yu H, Xu W, Xie X.
    Redox Biol; 2019 Jan 07; 20():247-260. PubMed ID: 30384259
    [Abstract] [Full Text] [Related]

  • 20. Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance.
    Lee JM.
    Diabetes Metab J; 2017 Feb 07; 41(1):10-19. PubMed ID: 28236381
    [Abstract] [Full Text] [Related]

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