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Journal Abstract Search

144 related items for PubMed ID: 18066777

  • 1. New developments of the "lock-in" modified cycloSal-d4TMPs.
    Vukadinović-Tenter D, Balzarini J, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1325-8. PubMed ID: 18066777
    [Abstract] [Full Text] [Related]

  • 2. Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides.
    Ducho C, Görbig U, Jessel S, Gisch N, Balzarini J, Meier C.
    J Med Chem; 2007 Mar 22; 50(6):1335-46. PubMed ID: 17328534
    [Abstract] [Full Text] [Related]

  • 3. Stereoselective synthesis and antiviral activity of methyl-substituted cycloSal-pronucleotides.
    Rios Morales EH, Balzarini J, Meier C.
    J Med Chem; 2012 Aug 23; 55(16):7245-52. PubMed ID: 22827702
    [Abstract] [Full Text] [Related]

  • 4. "Lock-in" modified cyclosal nucleotides--the second generation of cyclosal prodrugs.
    Vukadinović D, Böge NP, Balzarini J, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2005 Aug 23; 24(5-7):939-42. PubMed ID: 16248067
    [Abstract] [Full Text] [Related]

  • 5. Enzymatically activated cycloSal-d4T-monophosphates: The third generation of cycloSal-pronucleotides.
    Gisch N, Balzarini J, Meier C.
    J Med Chem; 2007 Apr 05; 50(7):1658-67. PubMed ID: 17335187
    [Abstract] [Full Text] [Related]

  • 6. cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.
    Meier C, Lorey M, De Clercq E, Balzarini J.
    J Med Chem; 1998 Apr 23; 41(9):1417-27. PubMed ID: 9554875
    [Abstract] [Full Text] [Related]

  • 7. Doubly loaded cycloSaligenyl-pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates).
    Gisch N, Balzarini J, Meier C.
    J Med Chem; 2009 Jun 11; 52(11):3464-73. PubMed ID: 19438207
    [Abstract] [Full Text] [Related]

  • 8. 5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine monophosphates, a second type of new, enzymatically activated cycloSaligenyl pronucleotides.
    Gisch N, Pertenbreiter F, Balzarini J, Meier C.
    J Med Chem; 2008 Dec 25; 51(24):8115-23. PubMed ID: 19053827
    [Abstract] [Full Text] [Related]

  • 9. Application of the cycloSal-prodrug approach for improving the biological potential of phosphorylated biomolecules.
    Meier C, Balzarini J.
    Antiviral Res; 2006 Sep 25; 71(2-3):282-92. PubMed ID: 16735066
    [Abstract] [Full Text] [Related]

  • 10. Diastereoselective synthesis of aryloxy phosphoramidate prodrugs of 3'-deoxy-2',3'-didehydrothymidine monophosphate.
    Roman CA, Balzarini J, Meier C.
    J Med Chem; 2010 Nov 11; 53(21):7675-81. PubMed ID: 20945915
    [Abstract] [Full Text] [Related]

  • 11. cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
    Meier C, Knispel T, De Clercq E, Balzarini J.
    J Med Chem; 1999 May 06; 42(9):1604-14. PubMed ID: 10229629
    [Abstract] [Full Text] [Related]

  • 12. 5-diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides.
    Gisch N, Balzarini J, Meier C.
    Nucleosides Nucleotides Nucleic Acids; 2007 May 06; 26(6-7):861-4. PubMed ID: 18066914
    [Abstract] [Full Text] [Related]

  • 13. d4TMP delivery from 7-substituted cycloSal-d4TMPs.
    Meier C, Renze JT, Balzarini J, De Clercq E.
    Nucleosides Nucleotides Nucleic Acids; 2003 May 06; 22(5-8):825-7. PubMed ID: 14565288
    [Abstract] [Full Text] [Related]

  • 14. Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity.
    Meier C, Muus U, Renze J, Naesens L, De Clercq E, Balzarini J.
    Antivir Chem Chemother; 2002 Mar 06; 13(2):101-14. PubMed ID: 12238528
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, stability, and biological evaluation of 1,3-dihydrobenzo[c]furan analogue of d4T and its SATE pronucleotide.
    Len C, Selouane A, Postel D, Villa P, Aubertin AM, Egron D, Gosselin G, Périgaud C.
    Nucleosides Nucleotides Nucleic Acids; 2003 Mar 06; 22(5-8):943-5. PubMed ID: 14565317
    [Abstract] [Full Text] [Related]

  • 16. Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription.
    Roy B, Chambert S, Lepoivre M, Aubertin AM, Balzarini J, Décout JL.
    J Med Chem; 2003 Jun 19; 46(13):2565-8. PubMed ID: 12801219
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR.
    Siddiqui AQ, McGuigan C, Ballatore C, Zuccotto F, Gilbert IH, De Clercq E, Balzarini J.
    J Med Chem; 1999 Oct 07; 42(20):4122-8. PubMed ID: 10514282
    [Abstract] [Full Text] [Related]

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  • 20. cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.
    Meiera C, Renzea J, Ducho C, Balzarini J.
    Curr Top Med Chem; 2002 Oct 07; 2(10):1111-21. PubMed ID: 12173970
    [Abstract] [Full Text] [Related]

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