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Journal Abstract Search

504 related items for PubMed ID: 18070930

  • 1. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
    Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L.
    Mol Pharmacol; 2008 Mar; 73(3):930-9. PubMed ID: 18070930
    [Abstract] [Full Text] [Related]

  • 2. The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.
    Razuvaev A, Henderson B, Girnita L, Larsson O, Axelson M, Hedin U, Roy J.
    J Vasc Surg; 2007 Jul; 46(1):108-15. PubMed ID: 17606126
    [Abstract] [Full Text] [Related]

  • 3. Role of ubiquitination in IGF-1 receptor signaling and degradation.
    Sehat B, Andersson S, Vasilcanu R, Girnita L, Larsson O.
    PLoS One; 2007 Apr 04; 2(4):e340. PubMed ID: 17406664
    [Abstract] [Full Text] [Related]

  • 4. Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells.
    Banno Y, Takuwa Y, Yamada M, Takuwa N, Ohguchi K, Hara A, Nozawa Y.
    Biochem J; 2003 Jan 15; 369(Pt 2):363-8. PubMed ID: 12385647
    [Abstract] [Full Text] [Related]

  • 5. Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells.
    Banudevi S, Senthilkumar K, Sharmila G, Arunkumar R, Vijayababu MR, Arunakaran J.
    Clin Chim Acta; 2010 Feb 15; 411(3-4):172-8. PubMed ID: 19913001
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
    Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A.
    Invest Ophthalmol Vis Sci; 2008 Jun 15; 49(6):2620-6. PubMed ID: 18515591
    [Abstract] [Full Text] [Related]

  • 7. Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.
    Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.
    Oncogene; 2006 Jan 12; 25(2):176-85. PubMed ID: 16170353
    [Abstract] [Full Text] [Related]

  • 8. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
    Strömberg T, Feng X, Delforoush M, Berglund M, Lin Y, Axelson M, Larsson O, Georgii-Hemming P, Lennartsson J, Enblad G.
    Med Oncol; 2015 Jul 12; 32(7):188. PubMed ID: 26021470
    [Abstract] [Full Text] [Related]

  • 9. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O, Almazan G.
    J Neurochem; 2009 Jun 12; 109(5):1440-51. PubMed ID: 19453943
    [Abstract] [Full Text] [Related]

  • 10. Tyrosine kinase-independent activation of extracellular-regulated kinase (ERK) 1/2 by the insulin-like growth factor-1 receptor.
    Perrault R, Wright B, Storie B, Hatherell A, Zahradka P.
    Cell Signal; 2011 Apr 12; 23(4):739-46. PubMed ID: 21215800
    [Abstract] [Full Text] [Related]

  • 11. IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.
    Borowiec AS, Hague F, Harir N, Guénin S, Guerineau F, Gouilleux F, Roudbaraki M, Lassoued K, Ouadid-Ahidouch H.
    J Cell Physiol; 2007 Sep 12; 212(3):690-701. PubMed ID: 17520698
    [Abstract] [Full Text] [Related]

  • 12. IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R-).
    Rosengren L, Vasilcanu D, Vasilcanu R, Fickenscher S, Sehat B, Natalishvili N, Naughton S, Yin S, Girnita A, Girnita L, Axelson M, Larsson O.
    Biochem Biophys Res Commun; 2006 Sep 08; 347(4):1059-66. PubMed ID: 16857168
    [Abstract] [Full Text] [Related]

  • 13. Expression of insulin-like growth factor-1 receptor, p-AKT and p-ERK1/2 protein in extramammary Paget's disease.
    Liu H, Moroi Y, Yasumoto S, Kokuba H, Imafuku S, Koga T, Masuda T, Tu Y, Furue M, Urabe K.
    Br J Dermatol; 2006 Sep 08; 155(3):586-91. PubMed ID: 16911286
    [Abstract] [Full Text] [Related]

  • 14. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
    Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L.
    Clin Cancer Res; 2006 Feb 15; 12(4):1383-91. PubMed ID: 16489097
    [Abstract] [Full Text] [Related]

  • 15. Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells.
    Fang J, Zhou Q, Shi XL, Jiang BH.
    Carcinogenesis; 2007 Mar 15; 28(3):713-23. PubMed ID: 17065200
    [Abstract] [Full Text] [Related]

  • 16. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
    Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L.
    Acta Ophthalmol; 2008 Nov 15; 86 Thesis 4():26-34. PubMed ID: 19032679
    [Abstract] [Full Text] [Related]

  • 17. Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma.
    Friedrichs N, Küchler J, Endl E, Koch A, Czerwitzki J, Wurst P, Metzger D, Schulte JH, Holst MI, Heukamp LC, Larsson O, Tanaka S, Kawai A, Wardelmann E, Buettner R, Pietsch T, Hartmann W.
    J Pathol; 2008 Dec 15; 216(4):428-39. PubMed ID: 18855347
    [Abstract] [Full Text] [Related]

  • 18. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
    Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O.
    Acta Ophthalmol; 2008 Nov 15; 86 Thesis 4():35-41. PubMed ID: 19032680
    [Abstract] [Full Text] [Related]

  • 19. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
    Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O.
    Invest Ophthalmol Vis Sci; 2008 Jun 15; 49(6):2337-42. PubMed ID: 18515579
    [Abstract] [Full Text] [Related]

  • 20. The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.
    Vasilcanu D, Girnita A, Girnita L, Vasilcanu R, Axelson M, Larsson O.
    Oncogene; 2004 Oct 14; 23(47):7854-62. PubMed ID: 15334055
    [Abstract] [Full Text] [Related]

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