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Journal Abstract Search


351 related items for PubMed ID: 18072756

  • 1. Role of Glu312 in binding and positioning of the substrate for the hydride transfer reaction in choline oxidase.
    Quaye O, Lountos GT, Fan F, Orville AM, Gadda G.
    Biochemistry; 2008 Jan 08; 47(1):243-56. PubMed ID: 18072756
    [Abstract] [Full Text] [Related]

  • 2. On the catalytic role of the conserved active site residue His466 of choline oxidase.
    Ghanem M, Gadda G.
    Biochemistry; 2005 Jan 25; 44(3):893-904. PubMed ID: 15654745
    [Abstract] [Full Text] [Related]

  • 3. Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue.
    Quaye O, Nguyen T, Gannavaram S, Pennati A, Gadda G.
    Arch Biochem Biophys; 2010 Jul 25; 499(1-2):1-5. PubMed ID: 20447376
    [Abstract] [Full Text] [Related]

  • 4. On the role of histidine 351 in the reaction of alcohol oxidation catalyzed by choline oxidase.
    Rungsrisuriyachai K, Gadda G.
    Biochemistry; 2008 Jul 01; 47(26):6762-9. PubMed ID: 18540638
    [Abstract] [Full Text] [Related]

  • 5. Role of asparagine 510 in the relative timing of substrate bond cleavages in the reaction catalyzed by choline oxidase.
    Rungsrisuriyachai K, Gadda G.
    Biochemistry; 2010 Mar 23; 49(11):2483-90. PubMed ID: 20163155
    [Abstract] [Full Text] [Related]

  • 6. Importance of a serine proximal to the C(4a) and N(5) flavin atoms for hydride transfer in choline oxidase.
    Yuan H, Gadda G.
    Biochemistry; 2011 Feb 08; 50(5):770-9. PubMed ID: 21174412
    [Abstract] [Full Text] [Related]

  • 7. On the contribution of the positively charged headgroup of choline to substrate binding and catalysis in the reaction catalyzed by choline oxidase.
    Gadda G, Fan F, Hoang JV.
    Arch Biochem Biophys; 2006 Jul 15; 451(2):182-7. PubMed ID: 16713988
    [Abstract] [Full Text] [Related]

  • 8. Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase.
    Quaye O, Gadda G.
    Arch Biochem Biophys; 2009 Sep 15; 489(1-2):10-4. PubMed ID: 19653994
    [Abstract] [Full Text] [Related]

  • 9. Substitution of an active site valine uncovers a kinetically slow equilibrium between competent and incompetent forms of choline oxidase.
    Finnegan S, Gadda G.
    Biochemistry; 2008 Dec 30; 47(52):13850-61. PubMed ID: 19053262
    [Abstract] [Full Text] [Related]

  • 10. Identification of the catalytic base for alcohol activation in choline oxidase.
    Smitherman C, Rungsrisuriyachai K, Germann MW, Gadda G.
    Biochemistry; 2015 Jan 20; 54(2):413-21. PubMed ID: 25478900
    [Abstract] [Full Text] [Related]

  • 11. Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling.
    Fan F, Gadda G.
    J Am Chem Soc; 2005 Dec 21; 127(50):17954-61. PubMed ID: 16351127
    [Abstract] [Full Text] [Related]

  • 12. Structural and kinetic studies on the Ser101Ala variant of choline oxidase: catalysis by compromise.
    Finnegan S, Yuan H, Wang YF, Orville AM, Weber IT, Gadda G.
    Arch Biochem Biophys; 2010 Sep 15; 501(2):207-13. PubMed ID: 20561507
    [Abstract] [Full Text] [Related]

  • 13. Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde.
    Fan F, Germann MW, Gadda G.
    Biochemistry; 2006 Feb 14; 45(6):1979-86. PubMed ID: 16460045
    [Abstract] [Full Text] [Related]

  • 14. An internal equilibrium preorganizes the enzyme-substrate complex for hydride tunneling in choline oxidase.
    Fan F, Gadda G.
    Biochemistry; 2007 May 29; 46(21):6402-8. PubMed ID: 17472346
    [Abstract] [Full Text] [Related]

  • 15. Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase.
    Ghanem M, Gadda G.
    Biochemistry; 2006 Mar 14; 45(10):3437-47. PubMed ID: 16519539
    [Abstract] [Full Text] [Related]

  • 16. The trimethylammonium headgroup of choline is a major determinant for substrate binding and specificity in choline oxidase.
    Gadda G, Powell NL, Menon P.
    Arch Biochem Biophys; 2004 Oct 15; 430(2):264-73. PubMed ID: 15369826
    [Abstract] [Full Text] [Related]

  • 17. On the catalytic mechanism of choline oxidase.
    Fan F, Gadda G.
    J Am Chem Soc; 2005 Feb 23; 127(7):2067-74. PubMed ID: 15713082
    [Abstract] [Full Text] [Related]

  • 18. Crystal structure of the 270 kDa homotetrameric lignin-degrading enzyme pyranose 2-oxidase.
    Hallberg BM, Leitner C, Haltrich D, Divne C.
    J Mol Biol; 2004 Aug 13; 341(3):781-96. PubMed ID: 15288786
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
    Yue QK, Kass IJ, Sampson NS, Vrielink A.
    Biochemistry; 1999 Apr 06; 38(14):4277-86. PubMed ID: 10194345
    [Abstract] [Full Text] [Related]

  • 20. The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity.
    Ilari A, Bonamore A, Franceschini S, Fiorillo A, Boffi A, Colotti G.
    Proteins; 2008 Jun 06; 71(4):2065-75. PubMed ID: 18186483
    [Abstract] [Full Text] [Related]


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