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Journal Abstract Search

182 related items for PubMed ID: 18085536

  • 1. 1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines.
    Hong J, Samudio I, Chintharlapalli S, Safe S.
    Mol Carcinog; 2008 Jul; 47(7):492-507. PubMed ID: 18085536
    [Abstract] [Full Text] [Related]

  • 2. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce apoptosis and inhibit renal cell carcinoma growth.
    York M, Abdelrahim M, Chintharlapalli S, Lucero SD, Safe S.
    Clin Cancer Res; 2007 Nov 15; 13(22 Pt 1):6743-52. PubMed ID: 18006776
    [Abstract] [Full Text] [Related]

  • 3. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways.
    Lei P, Abdelrahim M, Safe S.
    Mol Cancer Ther; 2006 Sep 15; 5(9):2324-36. PubMed ID: 16985067
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effects.
    Calabrò P, Samudio I, Safe SH, Willerson JT, Yeh ET.
    J Vasc Res; 2005 Sep 15; 42(6):509-16. PubMed ID: 16155367
    [Abstract] [Full Text] [Related]

  • 5. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways.
    Chintharlapalli S, Papineni S, Safe S.
    Mol Cancer Ther; 2006 May 15; 5(5):1362-70. PubMed ID: 16731770
    [Abstract] [Full Text] [Related]

  • 6. Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells.
    Guo J, Chintharlapalli S, Lee SO, Cho SD, Lei P, Papineni S, Safe S.
    Cancer Chemother Pharmacol; 2010 May 15; 66(1):141-50. PubMed ID: 19823826
    [Abstract] [Full Text] [Related]

  • 7. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit proliferation of estrogen receptor-negative breast cancer cells by activation of multiple pathways.
    Vanderlaag K, Su Y, Frankel AE, Grage H, Smith R, Khan S, Safe S.
    Breast Cancer Res Treat; 2008 May 15; 109(2):273-83. PubMed ID: 17624585
    [Abstract] [Full Text] [Related]

  • 8. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes are peroxisome proliferator-activated receptor gamma agonists but decrease HCT-116 colon cancer cell survival through receptor-independent activation of early growth response-1 and nonsteroidal anti-inflammatory drug-activated gene-1.
    Chintharlapalli S, Papineni S, Baek SJ, Liu S, Safe S.
    Mol Pharmacol; 2005 Dec 15; 68(6):1782-92. PubMed ID: 16155208
    [Abstract] [Full Text] [Related]

  • 9. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
    Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.
    BMC Cancer; 2010 Dec 03; 10():669. PubMed ID: 21129193
    [Abstract] [Full Text] [Related]

  • 10. 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.
    Abdelrahim M, Newman K, Vanderlaag K, Samudio I, Safe S.
    Carcinogenesis; 2006 Apr 03; 27(4):717-28. PubMed ID: 16332727
    [Abstract] [Full Text] [Related]

  • 11. Chemopreventive effects of synthetic C-substituted diindolylmethanes originating from cruciferous vegetables in human oral cancer cells.
    Shin JA, Shim JH, Choi ES, Leem DH, Kwon KH, Lee SO, Safe S, Cho NP, Cho SD.
    Eur J Cancer Prev; 2011 Sep 03; 20(5):417-25. PubMed ID: 21597379
    [Abstract] [Full Text] [Related]

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  • 13. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells.
    Chintharlapalli S, Smith R, Samudio I, Zhang W, Safe S.
    Cancer Res; 2004 Sep 01; 64(17):5994-6001. PubMed ID: 15342379
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  • 15. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
    Lei P, Abdelrahim M, Cho SD, Liu S, Chintharlapalli S, Safe S.
    Carcinogenesis; 2008 Jun 01; 29(6):1139-47. PubMed ID: 18460448
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  • 17. A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.
    Qin C, Morrow D, Stewart J, Spencer K, Porter W, Smith R, Phillips T, Abdelrahim M, Samudio I, Safe S.
    Mol Cancer Ther; 2004 Mar 01; 3(3):247-60. PubMed ID: 15026545
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  • 19. Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM.
    Vanderlaag K, Samudio I, Burghardt R, Barhoumi R, Safe S.
    Cancer Lett; 2006 May 18; 236(2):198-212. PubMed ID: 16051428
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of docetaxel anticancer activity by a novel diindolylmethane compound in human non-small cell lung cancer.
    Ichite N, Chougule MB, Jackson T, Fulzele SV, Safe S, Singh M.
    Clin Cancer Res; 2009 Jan 15; 15(2):543-52. PubMed ID: 19147759
    [Abstract] [Full Text] [Related]

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