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Journal Abstract Search

409 related items for PubMed ID: 18086127

  • 1. Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice.
    Gharami K, Xie Y, An JJ, Tonegawa S, Xu B.
    J Neurochem; 2008 Apr; 105(2):369-79. PubMed ID: 18086127
    [Abstract] [Full Text] [Related]

  • 2. BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice.
    Xie Y, Hayden MR, Xu B.
    J Neurosci; 2010 Nov 03; 30(44):14708-18. PubMed ID: 21048129
    [Abstract] [Full Text] [Related]

  • 3. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain.
    Ginés S, Bosch M, Marco S, Gavaldà N, Díaz-Hernández M, Lucas JJ, Canals JM, Alberch J.
    Eur J Neurosci; 2006 Feb 03; 23(3):649-58. PubMed ID: 16487146
    [Abstract] [Full Text] [Related]

  • 4. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
    Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W.
    Nat Med; 2011 Dec 18; 18(1):153-8. PubMed ID: 22179319
    [Abstract] [Full Text] [Related]

  • 5. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
    Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J.
    J Neurosci; 2004 Sep 01; 24(35):7727-39. PubMed ID: 15342740
    [Abstract] [Full Text] [Related]

  • 6. Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.
    Spires TL, Grote HE, Varshney NK, Cordery PM, van Dellen A, Blakemore C, Hannan AJ.
    J Neurosci; 2004 Mar 03; 24(9):2270-6. PubMed ID: 14999077
    [Abstract] [Full Text] [Related]

  • 7. Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.
    Brown TB, Bogush AI, Ehrlich ME.
    Hum Mol Genet; 2008 Oct 15; 17(20):3095-104. PubMed ID: 18632688
    [Abstract] [Full Text] [Related]

  • 8. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
    Liot G, Zala D, Pla P, Mottet G, Piel M, Saudou F.
    J Neurosci; 2013 Apr 10; 33(15):6298-309. PubMed ID: 23575829
    [Abstract] [Full Text] [Related]

  • 9. CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice.
    Apostol BL, Simmons DA, Zuccato C, Illes K, Pallos J, Casale M, Conforti P, Ramos C, Roarke M, Kathuria S, Cattaneo E, Marsh JL, Thompson LM.
    Mol Cell Neurosci; 2008 Sep 10; 39(1):8-20. PubMed ID: 18602275
    [Abstract] [Full Text] [Related]

  • 10. Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
    Gabery S, Sajjad MU, Hult S, Soylu R, Kirik D, Petersén Å.
    Eur J Neurosci; 2012 Sep 10; 36(6):2789-800. PubMed ID: 22731249
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
    Cho KJ, Lee BI, Cheon SY, Kim HW, Kim HJ, Kim GW.
    Neuroscience; 2009 Nov 10; 163(4):1128-34. PubMed ID: 19646509
    [Abstract] [Full Text] [Related]

  • 12. Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease.
    Bobrowska A, Paganetti P, Matthias P, Bates GP.
    PLoS One; 2011 Nov 10; 6(6):e20696. PubMed ID: 21677773
    [Abstract] [Full Text] [Related]

  • 13. Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.
    Zajac MS, Pang TY, Wong N, Weinrich B, Leang LS, Craig JM, Saffery R, Hannan AJ.
    Hippocampus; 2010 May 10; 20(5):621-36. PubMed ID: 19499586
    [Abstract] [Full Text] [Related]

  • 14. Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease.
    Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J.
    J Neurochem; 2005 Jun 10; 93(5):1057-68. PubMed ID: 15934928
    [Abstract] [Full Text] [Related]

  • 15. Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain.
    Fusco FR, Zuccato C, Tartari M, Martorana A, De March Z, Giampà C, Cattaneo E, Bernardi G.
    Eur J Neurosci; 2003 Sep 10; 18(5):1093-102. PubMed ID: 12956709
    [Abstract] [Full Text] [Related]

  • 16. Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease.
    Fatoba O, Kloster E, Reick C, Saft C, Gold R, Epplen JT, Arning L, Ellrichmann G.
    Exp Neurol; 2018 Apr 10; 302():112-128. PubMed ID: 29309751
    [Abstract] [Full Text] [Related]

  • 17. Relationship between BDNF expression in major striatal afferents, striatum morphology and motor behavior in the R6/2 mouse model of Huntington's disease.
    Samadi P, Boutet A, Rymar VV, Rawal K, Maheux J, Kvann JC, Tomaszewski M, Beaubien F, Cloutier JF, Levesque D, Sadikot AF.
    Genes Brain Behav; 2013 Feb 10; 12(1):108-24. PubMed ID: 23006318
    [Abstract] [Full Text] [Related]

  • 18. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E, Gafni J, Propp SS, Leavitt BR, Wellington CL, Young JE, Hackam AS, Logvinova AV, Peel AL, Chen SF, Hook V, Singaraja R, Krajewski S, Goldsmith PC, Ellerby HM, Hayden MR, Bredesen DE, Ellerby LM.
    Cell Death Differ; 2004 Apr 10; 11(4):424-38. PubMed ID: 14713958
    [Abstract] [Full Text] [Related]

  • 19. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.
    Brito V, Puigdellívol M, Giralt A, del Toro D, Alberch J, Ginés S.
    Cell Death Dis; 2013 Apr 18; 4(4):e595. PubMed ID: 23598407
    [Abstract] [Full Text] [Related]

  • 20. Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.
    Seo H, Kim W, Isacson O.
    Hum Mol Genet; 2008 Oct 15; 17(20):3144-53. PubMed ID: 18640989
    [Abstract] [Full Text] [Related]

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