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7. The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact p53 and pRb binding region do not have this effect. Goetz F, Tzeng YJ, Guhl E, Merker J, Graessmann M, Graessmann A. Oncogene; 2001 Apr 26; 20(18):2325-32. PubMed ID: 11402328 [Abstract] [Full Text] [Related]
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