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Journal Abstract Search


201 related items for PubMed ID: 18093923

  • 1. A potent cytotoxic photoactivated platinum complex.
    Mackay FS, Woods JA, Heringová P, Kaspárková J, Pizarro AM, Moggach SA, Parsons S, Brabec V, Sadler PJ.
    Proc Natl Acad Sci U S A; 2007 Dec 26; 104(52):20743-8. PubMed ID: 18093923
    [Abstract] [Full Text] [Related]

  • 2. Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.
    Zhao Y, Woods JA, Farrer NJ, Robinson KS, Pracharova J, Kasparkova J, Novakova O, Li H, Salassa L, Pizarro AM, Clarkson GJ, Song L, Brabec V, Sadler PJ.
    Chemistry; 2013 Jul 15; 19(29):9578-91. PubMed ID: 23733242
    [Abstract] [Full Text] [Related]

  • 3. Fast interstrand cross-linking of cisplatin-DNA monoadducts compared with intrastrand chelation: a kinetic study using hairpin-stabilized duplex oligonucleotides.
    Monjardet-Bas V, Chottard JC, Kozelka J.
    Chemistry; 2002 Mar 01; 8(5):1144-50. PubMed ID: 11891902
    [Abstract] [Full Text] [Related]

  • 4. Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs.
    Shi H, Romero-Canelón I, Hreusova M, Novakova O, Venkatesh V, Habtemariam A, Clarkson GJ, Song JI, Brabec V, Sadler PJ.
    Inorg Chem; 2018 Nov 19; 57(22):14409-14420. PubMed ID: 30365308
    [Abstract] [Full Text] [Related]

  • 5. Combined theoretical and computational study of interstrand DNA guanine-guanine cross-linking by trans-[Pt(pyridine)2] derived from the photoactivated prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2].
    Tai HC, Brodbeck R, Kasparkova J, Farrer NJ, Brabec V, Sadler PJ, Deeth RJ.
    Inorg Chem; 2012 Jun 18; 51(12):6830-41. PubMed ID: 22668523
    [Abstract] [Full Text] [Related]

  • 6. Interactions of DNA with a new platinum(IV) azide dipyridine complex activated by UVA and visible light: relationship to toxicity in tumor cells.
    Pracharova J, Zerzankova L, Stepankova J, Novakova O, Farrer NJ, Sadler PJ, Brabec V, Kasparkova J.
    Chem Res Toxicol; 2012 May 21; 25(5):1099-111. PubMed ID: 22420335
    [Abstract] [Full Text] [Related]

  • 7. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N.
    J Am Chem Soc; 2004 Feb 25; 126(7):2166-80. PubMed ID: 14971952
    [Abstract] [Full Text] [Related]

  • 8. Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
    Muchova T, Quintal SM, Farrell NP, Brabec V, Kasparkova J.
    J Biol Inorg Chem; 2012 Feb 25; 17(2):239-45. PubMed ID: 21938443
    [Abstract] [Full Text] [Related]

  • 9. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V, Kaspárková J, Vrána O, Nováková O, Cox JW, Qu Y, Farrell N.
    Biochemistry; 1999 May 25; 38(21):6781-90. PubMed ID: 10346899
    [Abstract] [Full Text] [Related]

  • 10. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
    Kasparkova J, Marini V, Najajreh Y, Gibson D, Brabec V.
    Biochemistry; 2003 May 27; 42(20):6321-32. PubMed ID: 12755637
    [Abstract] [Full Text] [Related]

  • 11. Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand.
    Frybortova M, Novakova O, Stepankova J, Novohradsky V, Gibson D, Kasparkova J, Brabec V.
    J Inorg Biochem; 2013 Sep 27; 126():46-54. PubMed ID: 23770803
    [Abstract] [Full Text] [Related]

  • 12. A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.
    Mackay FS, Woods JA, Moseley H, Ferguson J, Dawson A, Parsons S, Sadler PJ.
    Chemistry; 2006 Apr 03; 12(11):3155-61. PubMed ID: 16470886
    [Abstract] [Full Text] [Related]

  • 13. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J, Novakova O, Farrell N, Brabec V.
    Biochemistry; 2003 Jan 28; 42(3):792-800. PubMed ID: 12534292
    [Abstract] [Full Text] [Related]

  • 14. Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
    Ang WH, Myint M, Lippard SJ.
    J Am Chem Soc; 2010 Jun 02; 132(21):7429-35. PubMed ID: 20443565
    [Abstract] [Full Text] [Related]

  • 15. Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.
    Mlcouskova J, Malina J, Novohradsky V, Kasparkova J, Komeda S, Brabec V.
    Biochim Biophys Acta; 2012 Oct 02; 1820(10):1502-11. PubMed ID: 22683702
    [Abstract] [Full Text] [Related]

  • 16. Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(IV) complexes.
    Westendorf AF, Bodtke A, Bednarski PJ.
    Dalton Trans; 2011 May 21; 40(19):5342-51. PubMed ID: 21461431
    [Abstract] [Full Text] [Related]

  • 17. Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.
    Ali MS, Khan SR, Ojima H, Guzman IY, Whitmire KH, Siddik ZH, Khokhar AR.
    J Inorg Biochem; 2005 Mar 21; 99(3):795-804. PubMed ID: 15708801
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and X-ray crystal structure of trans,cis-[Pt(OAc)2I2(en)]: a novel type of cisplatin analog that can be photolyzed by visible light to DNA-binding and cytotoxic species in vitro.
    Kratochwil NA, Zabel M, Range KJ, Bednarski PJ.
    J Med Chem; 1996 Jun 21; 39(13):2499-507. PubMed ID: 8691447
    [Abstract] [Full Text] [Related]

  • 19. DNA cross-linking patterns induced by an antitumor-active trinuclear platinum complex and comparison with its dinuclear analogue.
    Zhu J, Zhao Y, Zhu Y, Wu Z, Lin M, He W, Wang Y, Chen G, Dong L, Zhang J, Lu Y, Guo Z.
    Chemistry; 2009 Jun 21; 15(21):5245-53. PubMed ID: 19350599
    [Abstract] [Full Text] [Related]

  • 20. Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites.
    Qu Y, Scarsdale NJ, Tran MC, Farrell NP.
    J Biol Inorg Chem; 2003 Jan 21; 8(1-2):19-28. PubMed ID: 12459895
    [Abstract] [Full Text] [Related]


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