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Journal Abstract Search

308 related items for PubMed ID: 18159922

  • 1. Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series.
    Kalinowski DS, Sharpe PC, Bernhardt PV, Richardson DR.
    J Med Chem; 2008 Jan 24; 51(2):331-44. PubMed ID: 18159922
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  • 2. Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: structure-activity relationships of novel thiohydrazone analogues.
    Kalinowski DS, Sharpe PC, Bernhardt PV, Richardson DR.
    J Med Chem; 2007 Nov 29; 50(24):6212-25. PubMed ID: 17963372
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  • 3. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR.
    J Med Chem; 2007 Jul 26; 50(15):3716-29. PubMed ID: 17602603
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  • 4. Unprecedented oxidation of a biologically active aroylhydrazone chelator catalysed by iron(III): serendipitous identification of diacylhydrazine ligands with high iron chelation efficacy.
    Bernhardt PV, Chin P, Richardson DR.
    J Biol Inorg Chem; 2001 Oct 26; 6(8):801-9. PubMed ID: 11713687
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  • 10. Future of toxicology--iron chelators and differing modes of action and toxicity: the changing face of iron chelation therapy.
    Kalinowski DS, Richardson DR.
    Chem Res Toxicol; 2007 May 26; 20(5):715-20. PubMed ID: 17402750
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  • 11. Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs.
    Becker E, Richardson DR.
    J Lab Clin Med; 1999 Nov 26; 134(5):510-21. PubMed ID: 10560945
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  • 12. Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues.
    Bernhardt PV, Mattsson J, Richardson DR.
    Inorg Chem; 2006 Jan 23; 45(2):752-60. PubMed ID: 16411711
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  • 13. Conjugates of desferrioxamine B (DFOB) with derivatives of adamantane or with orally available chelators as potential agents for treating iron overload.
    Liu J, Obando D, Schipanski LG, Groebler LK, Witting PK, Kalinowski DS, Richardson DR, Codd R.
    J Med Chem; 2010 Feb 11; 53(3):1370-82. PubMed ID: 20041672
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  • 18. Novel "hybrid" iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells.
    Lovejoy DB, Richardson DR.
    Blood; 2002 Jul 15; 100(2):666-76. PubMed ID: 12091363
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  • 19. Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
    Chaston TB, Watts RN, Yuan J, Richardson DR.
    Clin Cancer Res; 2004 Nov 01; 10(21):7365-74. PubMed ID: 15534113
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  • 20. Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.
    Bernhardt PV, Wilson GJ, Sharpe PC, Kalinowski DS, Richardson DR.
    J Biol Inorg Chem; 2008 Jan 01; 13(1):107-19. PubMed ID: 17899222
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