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141 related items for PubMed ID: 18163884

  • 1. Effects of gastric inhibitory polypeptide (GIP) and related analogues on glucagon release at normo- and hyperglycaemia in Wistar rats and isolated islets.
    Cassidy RS, Irwin N, Flatt PR.
    Biol Chem; 2008 Feb; 389(2):189-93. PubMed ID: 18163884
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide.
    Irwin N, Clarke GC, Green BD, Greer B, Harriott P, Gault VA, O'Harte FP, Flatt PR.
    Biochem Pharmacol; 2006 Sep 14; 72(6):719-28. PubMed ID: 16859646
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the subchronic antidiabetic effects of DPP IV-resistant GIP and GLP-1 analogues in obese diabetic (ob/ob) mice.
    Irwin N, McClean PL, Flatt PR.
    J Pept Sci; 2007 Jun 14; 13(6):400-5. PubMed ID: 17486662
    [Abstract] [Full Text] [Related]

  • 4. Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP(LysPAL16) and N-AcGIP(LysPAL37).
    Irwin N, Gault VA, Green BD, Greer B, Harriott P, Bailey CJ, Flatt PR, O'Harte FP.
    Biol Chem; 2005 Jul 14; 386(7):679-87. PubMed ID: 16207089
    [Abstract] [Full Text] [Related]

  • 5. A comparison of the cellular and biological properties of DPP-IV-resistant N-glucitol analogues of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide.
    Green BD, Gault VA, O'Harte FP, Flatt PR.
    Diabetes Obes Metab; 2005 Sep 14; 7(5):595-604. PubMed ID: 16050953
    [Abstract] [Full Text] [Related]

  • 6. The incretin hormones GIP and GLP-1 in diabetic rats: effects on insulin secretion and small bowel motility.
    Edholm T, Cejvan K, Abdel-Halim SM, Efendic S, Schmidt PT, Hellström PM.
    Neurogastroenterol Motil; 2009 Mar 14; 21(3):313-21. PubMed ID: 19126188
    [Abstract] [Full Text] [Related]

  • 7. Administration of an acylated GLP-1 and GIP preparation provides added beneficial glucose-lowering and insulinotropic actions over single incretins in mice with Type 2 diabetes and obesity.
    Gault VA, Kerr BD, Harriott P, Flatt PR.
    Clin Sci (Lond); 2011 Aug 14; 121(3):107-17. PubMed ID: 21332446
    [Abstract] [Full Text] [Related]

  • 8. Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties.
    Kerr BD, Irwin N, O'Harte FP, Bailey CJ, Flatt PR, Gault VA.
    Biochem Pharmacol; 2009 Oct 15; 78(8):1008-16. PubMed ID: 19523458
    [Abstract] [Full Text] [Related]

  • 9. Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness.
    Delmeire D, Flamez D, Moens K, Hinke SA, Van Schravendijk C, Pipeleers D, Schuit F.
    Biochem Pharmacol; 2004 Jul 01; 68(1):33-9. PubMed ID: 15183115
    [Abstract] [Full Text] [Related]

  • 10. Incretin and islet hormonal responses to fat and protein ingestion in healthy men.
    Carr RD, Larsen MO, Winzell MS, Jelic K, Lindgren O, Deacon CF, Ahrén B.
    Am J Physiol Endocrinol Metab; 2008 Oct 01; 295(4):E779-84. PubMed ID: 18612044
    [Abstract] [Full Text] [Related]

  • 11. Biological activity and antidiabetic potential of synthetic fragment peptides of glucose-dependent insulinotropic polypeptide, GIP(1-16) and (Pro3)GIP(1-16).
    Irwin N, Green BD, Parker JC, Gault VA, O'Harte FP, Flatt PR.
    Regul Pept; 2006 Jul 15; 135(1-2):45-53. PubMed ID: 16675042
    [Abstract] [Full Text] [Related]

  • 12. Stable agonist of glucose-dependent insulinotropic polypeptide (GIP) restores pancreatic beta cell glucose responsiveness but not glucose intolerance in aging mice.
    Irwin N, Green BD, Gault VA, Harriot P, O'Harte FP, Flatt PR.
    Exp Gerontol; 2006 Feb 15; 41(2):151-6. PubMed ID: 16378704
    [Abstract] [Full Text] [Related]

  • 13. What do we know about the secretion and degradation of incretin hormones?
    Deacon CF.
    Regul Pept; 2005 Jun 15; 128(2):117-24. PubMed ID: 15780431
    [Abstract] [Full Text] [Related]

  • 14. Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice.
    Pathak V, Gault VA, Flatt PR, Irwin N.
    Mol Cell Endocrinol; 2015 Feb 05; 401():120-9. PubMed ID: 25449420
    [Abstract] [Full Text] [Related]

  • 15. Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice.
    Irwin N, Gault VA, Green BD, Greer B, McCluskey JT, Harriott P, O'Harte FP, Flatt PR.
    Biol Chem; 2004 Sep 05; 385(9):845-52. PubMed ID: 15493880
    [Abstract] [Full Text] [Related]

  • 16. The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.
    Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Holst JJ, Krarup T.
    Regul Pept; 2007 Dec 04; 144(1-3):123-30. PubMed ID: 17692937
    [Abstract] [Full Text] [Related]

  • 17. Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.
    McShane LM, Irwin N, O'Flynn D, Franklin ZJ, Hewage CM, O'Harte FP.
    J Endocrinol; 2016 Jun 04; 229(3):319-30. PubMed ID: 27098830
    [Abstract] [Full Text] [Related]

  • 18. Evaluation of the insulinotropic and glucose-lowering actions of zebrafish GIP in mammalian systems: Evidence for involvement of the GLP-1 receptor.
    Graham GV, Conlon JM, Abdel-Wahab YH, Gault VA, Flatt PR.
    Peptides; 2018 Feb 04; 100():182-189. PubMed ID: 29157578
    [Abstract] [Full Text] [Related]

  • 19. Clinical endocrinology and metabolism. Glucose-dependent insulinotropic polypeptide/gastric inhibitory polypeptide.
    Meier JJ, Nauck MA.
    Best Pract Res Clin Endocrinol Metab; 2004 Dec 04; 18(4):587-606. PubMed ID: 15533777
    [Abstract] [Full Text] [Related]

  • 20. Glucose-dependent Insulinotropic Polypeptide (GIP): From prohormone to actions in endocrine pancreas and adipose tissue.
    Ugleholdt R.
    Dan Med Bull; 2011 Dec 04; 58(12):B4368. PubMed ID: 22142579
    [Abstract] [Full Text] [Related]

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