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354 related items for PubMed ID: 18166348

  • 1. Functional characterization of the novel APC N1026S variant associated with attenuated familial adenomatous polyposis.
    Menéndez M, González S, Obrador-Hevia A, Domínguez A, Pujol MJ, Valls J, Canela N, Blanco I, Torres A, Pineda-Lucena A, Moreno V, Bachs O, Capellá G.
    Gastroenterology; 2008 Jan; 134(1):56-64. PubMed ID: 18166348
    [Abstract] [Full Text] [Related]

  • 2. Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
    Venesio T, Balsamo A, Scordamaglia A, Bertolaso M, Arrigoni A, Sprujevnik T, Rossini FP, Risio M.
    Mod Pathol; 2003 Jan; 16(1):57-65. PubMed ID: 12527714
    [Abstract] [Full Text] [Related]

  • 3. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM, Brauburger K, Behrens J, Schneikert J.
    Oncogene; 2010 Mar 18; 29(11):1663-71. PubMed ID: 19966865
    [Abstract] [Full Text] [Related]

  • 4. Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.
    Kohler EM, Chandra SH, Behrens J, Schneikert J.
    Hum Mol Genet; 2009 Jan 15; 18(2):213-26. PubMed ID: 18854359
    [Abstract] [Full Text] [Related]

  • 5. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A, Kullmann F.
    Med Klin (Munich); 2003 Dec 15; 98(12):776-82. PubMed ID: 14685680
    [Abstract] [Full Text] [Related]

  • 6. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H, Sutter C, Kadmon M, Otto HF, Von Knebel-Doeberitz M, Gebert J, Helmke BM.
    Genes Chromosomes Cancer; 2004 Oct 15; 41(2):93-8. PubMed ID: 15287021
    [Abstract] [Full Text] [Related]

  • 7. Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene.
    Aretz S, Uhlhaas S, Sun Y, Pagenstecher C, Mangold E, Caspari R, Möslein G, Schulmann K, Propping P, Friedl W.
    Hum Mutat; 2004 Nov 15; 24(5):370-80. PubMed ID: 15459959
    [Abstract] [Full Text] [Related]

  • 8. Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis.
    Dihlmann S, Gebert J, Siermann A, Herfarth C, von Knebel Doeberitz M.
    Cancer Res; 1999 Apr 15; 59(8):1857-60. PubMed ID: 10213492
    [Abstract] [Full Text] [Related]

  • 9. Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
    Nielsen M, Hes FJ, Nagengast FM, Weiss MM, Mathus-Vliegen EM, Morreau H, Breuning MH, Wijnen JT, Tops CM, Vasen HF.
    Clin Genet; 2007 May 15; 71(5):427-33. PubMed ID: 17489848
    [Abstract] [Full Text] [Related]

  • 10. [From gene to disease; the APC gene and familial adenomatous polyposis coli].
    van der Luijt RB, Tops CM, Vasen HF.
    Ned Tijdschr Geneeskd; 2000 Oct 14; 144(42):2007-9. PubMed ID: 11072519
    [Abstract] [Full Text] [Related]

  • 11. Novel findings in Swedish patients with MYH-associated polyposis: mutation detection and clinical characterization.
    Kanter-Smoler G, Björk J, Fritzell K, Engwall Y, Hallberg B, Karlsson G, Grönberg H, Karlsson P, Wallgren A, Wahlström J, Hultcrantz R, Nordling M.
    Clin Gastroenterol Hepatol; 2006 Apr 14; 4(4):499-506. PubMed ID: 16616356
    [Abstract] [Full Text] [Related]

  • 12. Enhanced expression of cyclooxygenase-2 and nuclear beta-catenin are related to mutations in the APC gene in human colorectal cancer.
    Dimberg J, Hugander A, Sirsjö A, Söderkvist P.
    Anticancer Res; 2001 Apr 14; 21(2A):911-5. PubMed ID: 11396184
    [Abstract] [Full Text] [Related]

  • 13. APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis.
    Ficari F, Cama A, Valanzano R, Curia MC, Palmirotta R, Aceto G, Esposito DL, Crognale S, Lombardi A, Messerini L, Mariani-Costantini R, Tonelli F, Battista P.
    Br J Cancer; 2000 Jan 14; 82(2):348-53. PubMed ID: 10646887
    [Abstract] [Full Text] [Related]

  • 14. [Germline mutation of adenomatous polyposis coli gene in Chinese patients with familial adenomatous polyposis].
    Wang TT, Chen SQ, Zhang XM.
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2008 Apr 14; 25(2):199-202. PubMed ID: 18393246
    [Abstract] [Full Text] [Related]

  • 15. Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients.
    Inomata M, Ochiai A, Akimoto S, Kitano S, Hirohashi S.
    Cancer Res; 1996 May 01; 56(9):2213-7. PubMed ID: 8616874
    [Abstract] [Full Text] [Related]

  • 16. Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.
    Tomita H, Yamada Y, Oyama T, Hata K, Hirose Y, Hara A, Kunisada T, Sugiyama Y, Adachi Y, Linhart H, Mori H.
    Cancer Res; 2007 May 01; 67(9):4079-87. PubMed ID: 17483318
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.
    Yekkala K, Baudino TA.
    Mol Cancer Res; 2007 Dec 01; 5(12):1296-303. PubMed ID: 18171987
    [Abstract] [Full Text] [Related]

  • 18. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Gaujoux S, Pinson S, Gimenez-Roqueplo AP, Amar L, Ragazzon B, Launay P, Meatchi T, Libé R, Bertagna X, Audebourg A, Zucman-Rossi J, Tissier F, Bertherat J.
    Clin Cancer Res; 2010 Nov 01; 16(21):5133-41. PubMed ID: 20978149
    [Abstract] [Full Text] [Related]

  • 19. Colorectal cancer and genetic alterations in the Wnt pathway.
    Segditsas S, Tomlinson I.
    Oncogene; 2006 Dec 04; 25(57):7531-7. PubMed ID: 17143297
    [Abstract] [Full Text] [Related]

  • 20. Neurotensin receptor 1 gene activation by the Tcf/beta-catenin pathway is an early event in human colonic adenomas.
    Souazé F, Viardot-Foucault V, Roullet N, Toy-Miou-Leong M, Gompel A, Bruyneel E, Comperat E, Faux MC, Mareel M, Rostène W, Fléjou JF, Gespach C, Forgez P.
    Carcinogenesis; 2006 Apr 04; 27(4):708-16. PubMed ID: 16299383
    [Abstract] [Full Text] [Related]

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