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951 related items for PubMed ID: 18175316

  • 1. Structure-function relationship of inhibitory Smads: Structural flexibility contributes to functional divergence.
    Hariharan R, Pillai MR.
    Proteins; 2008 Jun; 71(4):1853-62. PubMed ID: 18175316
    [Abstract] [Full Text] [Related]

  • 2. Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif.
    Makkar P, Metpally RP, Sangadala S, Reddy BV.
    J Mol Graph Model; 2009 Apr; 27(7):803-12. PubMed ID: 19157940
    [Abstract] [Full Text] [Related]

  • 3. Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7.
    Inamoto S, Iwata S, Inamoto T, Nomura S, Sasaki T, Urasaki Y, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
    Oncogene; 2007 Feb 08; 26(6):893-904. PubMed ID: 16909115
    [Abstract] [Full Text] [Related]

  • 4. Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling.
    Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K.
    J Biol Chem; 2004 Jul 23; 279(30):31568-74. PubMed ID: 15148321
    [Abstract] [Full Text] [Related]

  • 5. The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
    Hanyu A, Ishidou Y, Ebisawa T, Shimanuki T, Imamura T, Miyazono K.
    J Cell Biol; 2001 Dec 10; 155(6):1017-27. PubMed ID: 11739411
    [Abstract] [Full Text] [Related]

  • 6. Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells.
    Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K.
    Bone; 2006 Feb 10; 38(2):206-14. PubMed ID: 16203197
    [Abstract] [Full Text] [Related]

  • 7. Regulation of transforming growth factor-beta signaling.
    Zhu HJ, Burgess AW.
    Mol Cell Biol Res Commun; 2001 Nov 10; 4(6):321-30. PubMed ID: 11703090
    [Abstract] [Full Text] [Related]

  • 8. Homology modeling of the DNA-binding domain of human Smad5: a molecular model for inhibitor design.
    Hariharan R, Pillai MR.
    J Mol Graph Model; 2006 Jan 10; 24(4):271-7. PubMed ID: 16243555
    [Abstract] [Full Text] [Related]

  • 9. Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction.
    Kuang C, Chen Y.
    Oncogene; 2004 Feb 05; 23(5):1021-9. PubMed ID: 14647410
    [Abstract] [Full Text] [Related]

  • 10. Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation.
    Zhang S, Fei T, Zhang L, Zhang R, Chen F, Ning Y, Han Y, Feng XH, Meng A, Chen YG.
    Mol Cell Biol; 2007 Jun 05; 27(12):4488-99. PubMed ID: 17438144
    [Abstract] [Full Text] [Related]

  • 11. Molecular characterisation of a second structurally unusual AR-Smad without an MH1 domain and a Smad4 orthologue from Echinococcus multilocularis.
    Zavala-Góngora R, Derrer B, Gelmedin V, Knaus P, Brehm K.
    Int J Parasitol; 2008 Feb 05; 38(2):161-76. PubMed ID: 17845804
    [Abstract] [Full Text] [Related]

  • 12. Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma.
    Liu X, Lee J, Cooley M, Bhogte E, Hartley S, Glick A.
    Cancer Res; 2003 Nov 15; 63(22):7760-8. PubMed ID: 14633701
    [Abstract] [Full Text] [Related]

  • 13. Prognostic value of the expression of Smad6 and Smad7, as inhibitory Smads of the TGF-beta superfamily, in esophageal squamous cell carcinoma.
    Osawa H, Nakajima M, Kato H, Fukuchi M, Kuwano H.
    Anticancer Res; 2004 Nov 15; 24(6):3703-9. PubMed ID: 15736400
    [Abstract] [Full Text] [Related]

  • 14. Structural basis for inhibitory effects of Smad7 on TGF-β family signaling.
    Murayama K, Kato-Murayama M, Itoh Y, Miyazono K, Miyazawa K, Shirouzu M.
    J Struct Biol; 2020 Dec 01; 212(3):107661. PubMed ID: 33166654
    [Abstract] [Full Text] [Related]

  • 15. Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.
    Christian JL, Nakayama T.
    Bioessays; 1999 May 01; 21(5):382-90. PubMed ID: 10376010
    [Abstract] [Full Text] [Related]

  • 16. Localization of Smad6 and Smad7 in the rat kidney and their regulated expression in the anti-Thy-1 nephritis.
    Uchida K, Nitta K, Kobayashi H, Kawachi H, Shimizu F, Yumura W, Nihei H.
    Mol Cell Biol Res Commun; 2000 Aug 01; 4(2):98-105. PubMed ID: 11170839
    [Abstract] [Full Text] [Related]

  • 17. Echinococcus multilocularis: molecular characterization of EmSmadE, a novel BR-Smad involved in TGF-β and BMP signaling.
    Epping K, Brehm K.
    Exp Parasitol; 2011 Oct 01; 129(2):85-94. PubMed ID: 21802416
    [Abstract] [Full Text] [Related]

  • 18. IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.
    Weng H, Mertens PR, Gressner AM, Dooley S.
    J Hepatol; 2007 Feb 01; 46(2):295-303. PubMed ID: 17125875
    [Abstract] [Full Text] [Related]

  • 19. The Delta intracellular domain mediates TGF-beta/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway.
    Hiratochi M, Nagase H, Kuramochi Y, Koh CS, Ohkawara T, Nakayama K.
    Nucleic Acids Res; 2007 Feb 01; 35(3):912-22. PubMed ID: 17251195
    [Abstract] [Full Text] [Related]

  • 20. Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.
    Imoto S, Sugiyama K, Sekine Y, Matsuda T.
    FEBS Lett; 2005 May 23; 579(13):2853-62. PubMed ID: 15907489
    [Abstract] [Full Text] [Related]

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