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Journal Abstract Search

86 related items for PubMed ID: 18191824

  • 1. The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
    Narimatsu S, Kiryu K, Yonemoto R, Yoshino M, Kobatake M, Kazamori D, Hagino S, Masuda K, Katsu T, Asanuma M, Kumamoto T, Ishikawa T, Funae Y, Yamano S, Hanioka N, Naito S.
    Chem Biol Interact; 2008 Mar 10; 172(1):11-21. PubMed ID: 18191824
    [Abstract] [Full Text] [Related]

  • 2. The roles of amino acid residues at positions 43 and 45 in microsomal contents and enzymatic functions of rat CYP2D1 and CYP2D2.
    Narimatsu S, Imoto K, Isobe T, Kiryu K, Naito S, Hichiya H, Funae Y, Hanioka N, Yamamoto S.
    Biochem Biophys Res Commun; 2004 Nov 12; 324(2):627-33. PubMed ID: 15474473
    [Abstract] [Full Text] [Related]

  • 3. Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N.
    Biochem Pharmacol; 2006 Apr 28; 71(9):1377-85. PubMed ID: 16510126
    [Abstract] [Full Text] [Related]

  • 4. Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N.
    Biochem Pharmacol; 2008 Feb 01; 75(3):752-60. PubMed ID: 17980859
    [Abstract] [Full Text] [Related]

  • 5. Rat CYP2D2, not 2D1, is functionally conserved with human CYP2D6 in endogenous morphine formation.
    Grobe N, Kutchan TM, Zenk MH.
    FEBS Lett; 2012 Jun 21; 586(13):1749-53. PubMed ID: 22641033
    [Abstract] [Full Text] [Related]

  • 6. Cloning and characterization of the CYP2D1-binding protein, retinol dehydrogenase.
    Imaoka S, Wan J, Chow T, Hiroi T, Eyanagi R, Shigematsu H, Funae Y.
    Arch Biochem Biophys; 1998 May 15; 353(2):331-6. PubMed ID: 9606967
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS.
    Caspar AT, Gaab JB, Michely JA, Brandt SD, Meyer MR, Maurer HH.
    Drug Test Anal; 2018 Jan 15; 10(1):184-195. PubMed ID: 28342193
    [Abstract] [Full Text] [Related]

  • 8. Stereoselective hexobarbital 3'-hydroxylation by CYP2C19 expressed in yeast cells and the roles of amino acid residues at positions 300 and 476.
    Saito K, Dan H, Masuda K, Katsu T, Hanioka N, Yamamoto S, Miyano K, Yamano S, Narimatsu S.
    Chirality; 2007 Jul 15; 19(7):550-8. PubMed ID: 17487889
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N,N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites.
    Kamata T, Katagi M, Kamata HT, Miki A, Shima N, Zaitsu K, Nishikawa M, Tanaka E, Honda K, Tsuchihashi H.
    Drug Metab Dispos; 2006 Feb 15; 34(2):281-7. PubMed ID: 16280455
    [Abstract] [Full Text] [Related]

  • 10. Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity.
    Wan J, Imaoka S, Chow T, Hiroi T, Yabusaki Y, Funae Y.
    Arch Biochem Biophys; 1997 Dec 15; 348(2):383-90. PubMed ID: 9434752
    [Abstract] [Full Text] [Related]

  • 11. Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.
    Venhorst J, ter Laak AM, Commandeur JN, Funae Y, Hiroi T, Vermeulen NP.
    J Med Chem; 2003 Jan 02; 46(1):74-86. PubMed ID: 12502361
    [Abstract] [Full Text] [Related]

  • 12. The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol.
    Narimatsu S, Kazamori D, Masuda K, Katsu T, Funae Y, Naito S, Nakura H, Yamano S, Hanioka N.
    Biochem Pharmacol; 2009 Mar 01; 77(5):920-31. PubMed ID: 19059219
    [Abstract] [Full Text] [Related]

  • 13. Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11.
    Liu J, He YA, Halpert JR.
    Arch Biochem Biophys; 1996 Mar 01; 327(1):167-73. PubMed ID: 8615687
    [Abstract] [Full Text] [Related]

  • 14. Importance of CYP2D3 in polymorphism of diazepam p-hydroxylation in rats.
    Sakai N, Saito K, Kim HS, Kazusaka A, Ishizuka M, Funae Y, Fujita S.
    Drug Metab Dispos; 2005 Nov 01; 33(11):1657-60. PubMed ID: 16081673
    [Abstract] [Full Text] [Related]

  • 15. Different effects of desipramine on bufuralol 1''-hydroxylation by rat and human CYP2D enzymes.
    Isobe T, Hichiya H, Hanioka N, Yamamoto S, Shinoda S, Funae Y, Satoh T, Yamano S, Narimatsu S.
    Biol Pharm Bull; 2005 Apr 01; 28(4):634-40. PubMed ID: 15802801
    [Abstract] [Full Text] [Related]

  • 16. Isoform-selective metabolism of mianserin by cytochrome P-450 2D.
    Chow T, Hiroi T, Imaoka S, Chiba K, Funae Y.
    Drug Metab Dispos; 1999 Oct 01; 27(10):1200-4. PubMed ID: 10497148
    [Abstract] [Full Text] [Related]

  • 17. Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2.
    Yamamoto Y, Tasaki T, Nakamura A, Iwata H, Kazusaka A, Gonzalez FJ, Fujita S.
    Pharmacogenetics; 1998 Feb 01; 8(1):73-82. PubMed ID: 9511184
    [Abstract] [Full Text] [Related]

  • 18. Cloning and functional expression of a novel marmoset cytochrome P450 2D enzyme, CYP2D30: comparison with the known marmoset CYP2D19.
    Hichiya H, Kuramoto S, Yamamoto S, Shinoda S, Hanioka N, Narimatsu S, Asaoka K, Miyata A, Iwata S, Nomoto M, Satoh T, Kiryu K, Ueda N, Naito S, Tucker GT, Ellis SW.
    Biochem Pharmacol; 2004 Jul 01; 68(1):165-75. PubMed ID: 15183128
    [Abstract] [Full Text] [Related]

  • 19. Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats.
    Fantegrossi WE, Harrington AW, Kiessel CL, Eckler JR, Rabin RA, Winter JC, Coop A, Rice KC, Woods JH.
    Pharmacol Biochem Behav; 2006 Jan 01; 83(1):122-9. PubMed ID: 16460788
    [Abstract] [Full Text] [Related]

  • 20. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling.
    Spatzenegger M, Liu H, Wang Q, Debarber A, Koop DR, Halpert JR.
    J Pharmacol Exp Ther; 2003 Jan 01; 304(1):477-87. PubMed ID: 12490624
    [Abstract] [Full Text] [Related]

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