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252 related items for PubMed ID: 18192694

  • 1. 15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS.
    Kim EH, Na HK, Kim DH, Park SA, Kim HN, Song NY, Surh YJ.
    Carcinogenesis; 2008 Apr; 29(4):688-95. PubMed ID: 18192694
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism.
    Grau R, Iñiguez MA, Fresno M.
    Cancer Res; 2004 Aug 01; 64(15):5162-71. PubMed ID: 15289320
    [Abstract] [Full Text] [Related]

  • 3. 15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species.
    Kitz K, Windischhofer W, Leis HJ, Huber E, Kollroser M, Malle E.
    Free Radic Biol Med; 2011 Apr 01; 50(7):854-65. PubMed ID: 21236332
    [Abstract] [Full Text] [Related]

  • 4. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Shin SW, Seo CY, Han H, Han JY, Jeong JS, Kwak JY, Park JI.
    Clin Cancer Res; 2009 Sep 01; 15(17):5414-25. PubMed ID: 19690198
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism.
    Farrajota K, Cheng S, Martel-Pelletier J, Afif H, Pelletier JP, Li X, Ranger P, Fahmi H.
    Arthritis Rheum; 2005 Jan 01; 52(1):94-104. PubMed ID: 15641079
    [Abstract] [Full Text] [Related]

  • 6. Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.
    Song NY, Kim DH, Kim EH, Na HK, Kim NJ, Suh YG, Surh YJ.
    Chem Res Toxicol; 2011 Aug 15; 24(8):1231-41. PubMed ID: 21728338
    [Abstract] [Full Text] [Related]

  • 7. Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells.
    Liu JD, Lin SY, Ho YS, Pan S, Hung LF, Tsai SH, Lin JK, Liang YC.
    Mol Carcinog; 2003 May 15; 37(1):16-24. PubMed ID: 12720296
    [Abstract] [Full Text] [Related]

  • 8. The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1.
    Jung WK, Park IS, Park SJ, Yea SS, Choi YH, Oh S, Park SG, Choi IW.
    Life Sci; 2009 Jul 03; 85(1-2):46-53. PubMed ID: 19409914
    [Abstract] [Full Text] [Related]

  • 9. Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.
    Sánchez-Gómez FJ, Cernuda-Morollón E, Stamatakis K, Pérez-Sala D.
    Mol Pharmacol; 2004 Nov 03; 66(5):1349-58. PubMed ID: 15317873
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells.
    Kondoh K, Tsuji N, Asanuma K, Kobayashi D, Watanabe N.
    Exp Cell Res; 2007 Oct 01; 313(16):3486-96. PubMed ID: 17706193
    [Abstract] [Full Text] [Related]

  • 11. 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells.
    Lee DR, Kwon CH, Park JY, Kim YK, Woo JS.
    Toxicology; 2009 Apr 05; 258(1):17-24. PubMed ID: 19167456
    [Abstract] [Full Text] [Related]

  • 12. An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome.
    Shibata T, Yamada T, Kondo M, Tanahashi N, Tanaka K, Nakamura H, Masutani H, Yodoi J, Uchida K.
    Biochemistry; 2003 Dec 02; 42(47):13960-8. PubMed ID: 14636064
    [Abstract] [Full Text] [Related]

  • 13. 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state.
    Katura T, Moriya T, Nakahata N.
    Mol Pharmacol; 2010 Apr 02; 77(4):601-11. PubMed ID: 20086036
    [Abstract] [Full Text] [Related]

  • 14. Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis.
    Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
    Clin Cancer Res; 2010 Apr 15; 16(8):2320-32. PubMed ID: 20371690
    [Abstract] [Full Text] [Related]

  • 15. Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.
    Shen ZN, Nishida K, Doi H, Oohashi T, Hirohata S, Ozaki T, Yoshida A, Ninomiya Y, Inoue H.
    Biochem Biophys Res Commun; 2005 Mar 11; 328(2):375-82. PubMed ID: 15694358
    [Abstract] [Full Text] [Related]

  • 16. Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2).
    Campo PA, Das S, Hsiang CH, Bui T, Samuel CE, Straus DS.
    Cell Growth Differ; 2002 Sep 11; 13(9):409-20. PubMed ID: 12354750
    [Abstract] [Full Text] [Related]

  • 17. Peroxisome proliferator-activated receptor-gamma suppresses cyclooxygenase-2 expression in human prostate cells.
    Sabichi AL, Subbarayan V, Llansa N, Lippman SM, Menter DG.
    Cancer Epidemiol Biomarkers Prev; 2004 Nov 11; 13(11 Pt 1):1704-9. PubMed ID: 15533896
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.
    Fionda C, Nappi F, Piccoli M, Frati L, Santoni A, Cippitelli M.
    Mol Pharmacol; 2007 Nov 11; 72(5):1246-57. PubMed ID: 17673570
    [Abstract] [Full Text] [Related]

  • 19. 15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression.
    Kamagata C, Tsuji N, Moriai M, Kobayashi D, Watanabe N.
    Breast Cancer Res Treat; 2007 May 11; 102(3):263-73. PubMed ID: 17028981
    [Abstract] [Full Text] [Related]

  • 20. 15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation.
    Han H, Shin SW, Seo CY, Kwon HC, Han JY, Kim IH, Kwak JY, Park JI.
    Apoptosis; 2007 Nov 11; 12(11):2101-14. PubMed ID: 17786557
    [Abstract] [Full Text] [Related]

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