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Journal Abstract Search

699 related items for PubMed ID: 18194654

  • 1. Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila.
    Sykiotis GP, Bohmann D.
    Dev Cell; 2008 Jan; 14(1):76-85. PubMed ID: 18194654
    [Abstract] [Full Text] [Related]

  • 2. Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles.
    Turpaev KT.
    Biochemistry (Mosc); 2013 Feb; 78(2):111-26. PubMed ID: 23581983
    [Abstract] [Full Text] [Related]

  • 3. Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.
    Probst BL, McCauley L, Trevino I, Wigley WC, Ferguson DA.
    PLoS One; 2015 Feb; 10(8):e0135257. PubMed ID: 26301506
    [Abstract] [Full Text] [Related]

  • 4. Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.
    Ohta T, Iijima K, Miyamoto M, Nakahara I, Tanaka H, Ohtsuji M, Suzuki T, Kobayashi A, Yokota J, Sakiyama T, Shibata T, Yamamoto M, Hirohashi S.
    Cancer Res; 2008 Mar 01; 68(5):1303-9. PubMed ID: 18316592
    [Abstract] [Full Text] [Related]

  • 5. The Keap1-Nrf2 system and diabetes mellitus.
    Uruno A, Yagishita Y, Yamamoto M.
    Arch Biochem Biophys; 2015 Jan 15; 566():76-84. PubMed ID: 25528168
    [Abstract] [Full Text] [Related]

  • 6. Mechanistic studies of the Nrf2-Keap1 signaling pathway.
    Zhang DD.
    Drug Metab Rev; 2006 Jan 15; 38(4):769-89. PubMed ID: 17145701
    [Abstract] [Full Text] [Related]

  • 7. The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation.
    Bryan HK, Olayanju A, Goldring CE, Park BK.
    Biochem Pharmacol; 2013 Mar 15; 85(6):705-17. PubMed ID: 23219527
    [Abstract] [Full Text] [Related]

  • 8. Nrf2 protects against airway disorders.
    Cho HY, Kleeberger SR.
    Toxicol Appl Pharmacol; 2010 Apr 01; 244(1):43-56. PubMed ID: 19646463
    [Abstract] [Full Text] [Related]

  • 9. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z, Zhang S, Chan JY, Zhang DD.
    Mol Cell Biol; 2007 Sep 01; 27(18):6334-49. PubMed ID: 17636022
    [Abstract] [Full Text] [Related]

  • 10. Nrf2: friend and foe in preventing cigarette smoking-dependent lung disease.
    Müller T, Hengstermann A.
    Chem Res Toxicol; 2012 Sep 17; 25(9):1805-24. PubMed ID: 22686525
    [Abstract] [Full Text] [Related]

  • 11. Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old.
    Safdar A, deBeer J, Tarnopolsky MA.
    Free Radic Biol Med; 2010 Nov 30; 49(10):1487-93. PubMed ID: 20708680
    [Abstract] [Full Text] [Related]

  • 12. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.
    Giudice A, Arra C, Turco MC.
    Methods Mol Biol; 2010 Nov 30; 647():37-74. PubMed ID: 20694660
    [Abstract] [Full Text] [Related]

  • 13. Keap1 mutations and Nrf2 pathway activation in epithelial ovarian cancer.
    Konstantinopoulos PA, Spentzos D, Fountzilas E, Francoeur N, Sanisetty S, Grammatikos AP, Hecht JL, Cannistra SA.
    Cancer Res; 2011 Aug 01; 71(15):5081-9. PubMed ID: 21676886
    [Abstract] [Full Text] [Related]

  • 14. Dysregulation of the Keap1-Nrf2 pathway in cancer.
    Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL.
    Biochem Soc Trans; 2015 Aug 01; 43(4):645-9. PubMed ID: 26551706
    [Abstract] [Full Text] [Related]

  • 15. Epigenetic regulation of Keap1-Nrf2 signaling.
    Guo Y, Yu S, Zhang C, Kong AN.
    Free Radic Biol Med; 2015 Nov 01; 88(Pt B):337-349. PubMed ID: 26117320
    [Abstract] [Full Text] [Related]

  • 16. Toward clinical application of the Keap1-Nrf2 pathway.
    Suzuki T, Motohashi H, Yamamoto M.
    Trends Pharmacol Sci; 2013 Jun 01; 34(6):340-6. PubMed ID: 23664668
    [Abstract] [Full Text] [Related]

  • 17. Immunohistochemical study of the Nrf2 pathway in colorectal cancer: Nrf2 expression is closely correlated to Keap1 in the tumor and Bach1 in the normal tissue.
    Chang LC, Fan CW, Tseng WK, Chen JR, Chein HP, Hwang CC, Hua CC.
    Appl Immunohistochem Mol Morphol; 2013 Dec 01; 21(6):511-7. PubMed ID: 23455180
    [Abstract] [Full Text] [Related]

  • 18. Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance.
    Jeddi F, Soozangar N, Sadeghi MR, Somi MH, Samadi N.
    DNA Repair (Amst); 2017 Jun 01; 54():13-21. PubMed ID: 28415030
    [Abstract] [Full Text] [Related]

  • 19. Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice.
    Yueh MF, Tukey RH.
    J Biol Chem; 2007 Mar 23; 282(12):8749-58. PubMed ID: 17259171
    [Abstract] [Full Text] [Related]

  • 20. NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer.
    Hayes JD, McMahon M.
    Trends Biochem Sci; 2009 Apr 23; 34(4):176-88. PubMed ID: 19321346
    [Abstract] [Full Text] [Related]

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