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Journal Abstract Search

130 related items for PubMed ID: 18205296

  • 1. Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.
    Liénard BM, Hüting R, Lassaux P, Galleni M, Frère JM, Schofield CJ.
    J Med Chem; 2008 Feb 14; 51(3):684-8. PubMed ID: 18205296
    [Abstract] [Full Text] [Related]

  • 2. Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-beta-lactamases.
    Siemann S, Clarke AJ, Viswanatha T, Dmitrienko GI.
    Biochemistry; 2003 Feb 18; 42(6):1673-83. PubMed ID: 12578382
    [Abstract] [Full Text] [Related]

  • 3. Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.
    Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ.
    Org Biomol Chem; 2008 Jul 07; 6(13):2282-94. PubMed ID: 18563261
    [Abstract] [Full Text] [Related]

  • 4. Irreversible inhibition of metallo-beta-lactamase (IMP-1) by 3-(3-mercaptopropionylsulfanyl)propionic acid pentafluorophenyl ester.
    Kurosaki H, Yamaguchi Y, Higashi T, Soga K, Matsueda S, Yumoto H, Misumi S, Yamagata Y, Arakawa Y, Goto M.
    Angew Chem Int Ed Engl; 2005 Jun 20; 44(25):3861-4. PubMed ID: 15892033
    [No Abstract] [Full Text] [Related]

  • 5. Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups.
    Kurosaki H, Yamaguchi Y, Yasuzawa H, Jin W, Yamagata Y, Arakawa Y.
    ChemMedChem; 2006 Sep 20; 1(9):969-72. PubMed ID: 16937423
    [No Abstract] [Full Text] [Related]

  • 6. Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.
    Lassaux P, Hamel M, Gulea M, Delbrück H, Mercuri PS, Horsfall L, Dehareng D, Kupper M, Frère JM, Hoffmann K, Galleni M, Bebrone C.
    J Med Chem; 2010 Jul 08; 53(13):4862-76. PubMed ID: 20527888
    [Abstract] [Full Text] [Related]

  • 7. Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors.
    Liénard BM, Selevsek N, Oldham NJ, Schofield CJ.
    ChemMedChem; 2007 Feb 08; 2(2):175-9. PubMed ID: 17206734
    [No Abstract] [Full Text] [Related]

  • 8. Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis.
    Sun Q, Law A, Crowder MW, Geysen HM.
    Bioorg Med Chem Lett; 2006 Oct 01; 16(19):5169-75. PubMed ID: 16875814
    [Abstract] [Full Text] [Related]

  • 9. Inhibitors of the FEZ-1 metallo-beta-lactamase.
    Liénard BM, Horsfall LE, Galleni M, Frère JM, Schofield CJ.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):964-8. PubMed ID: 17157014
    [Abstract] [Full Text] [Related]

  • 10. New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design.
    Olsen L, Jost S, Adolph HW, Pettersson I, Hemmingsen L, Jørgensen FS.
    Bioorg Med Chem; 2006 Apr 15; 14(8):2627-35. PubMed ID: 16378729
    [Abstract] [Full Text] [Related]

  • 11. Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.
    Thomson JM, Distler AM, Bonomo RA.
    Biochemistry; 2007 Oct 09; 46(40):11361-8. PubMed ID: 17848099
    [Abstract] [Full Text] [Related]

  • 12. Zinc-bound thiolate-disulfide exchange: a strategy for inhibiting metallo-beta-lactamases.
    Boerzel H, Koeckert M, Bu W, Spingler B, Lippard SJ.
    Inorg Chem; 2003 Mar 10; 42(5):1604-15. PubMed ID: 12611529
    [Abstract] [Full Text] [Related]

  • 13. 68Zn isotope exchange experiments reveal an unusual kinetic lability of the metal ions in the di-zinc form of IMP-1 metallo-beta-lactamase.
    Siemann S, Badiei HR, Karanassios V, Viswanatha T, Dmitrienko GI.
    Chem Commun (Camb); 2006 Feb 07; (5):532-4. PubMed ID: 16432573
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry.
    Tabei K, Feng X, Venkatesan AM, Abe T, Hideki U, Mansour TS, Siegel MM.
    J Med Chem; 2004 Jul 01; 47(14):3674-88. PubMed ID: 15214794
    [Abstract] [Full Text] [Related]

  • 15. Metal content and localization during turnover in B. cereus metallo-beta-lactamase.
    Llarrull LI, Tioni MF, Vila AJ.
    J Am Chem Soc; 2008 Nov 26; 130(47):15842-51. PubMed ID: 18980306
    [Abstract] [Full Text] [Related]

  • 16. Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases.
    Simm AM, Loveridge EJ, Crosby J, Avison MB, Walsh TR, Bennett PM.
    Biochem J; 2005 May 01; 387(Pt 3):585-90. PubMed ID: 15569001
    [Abstract] [Full Text] [Related]

  • 17. Inhibition studies on the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia.
    Yang KW, Crowder MW.
    Arch Biochem Biophys; 1999 Aug 01; 368(1):1-6. PubMed ID: 10415104
    [Abstract] [Full Text] [Related]

  • 18. Inhibitors of metallo-beta-lactamase generated from beta-lactam antibiotics.
    Badarau A, Llinás A, Laws AP, Damblon C, Page MI.
    Biochemistry; 2005 Jun 21; 44(24):8578-89. PubMed ID: 15952764
    [Abstract] [Full Text] [Related]

  • 19. Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry.
    Selevsek N, Tholey A, Heinzle E, Liénard BM, Oldham NJ, Schofield CJ, Heinz U, Adolph HW, Frère JM.
    J Am Soc Mass Spectrom; 2006 Jul 21; 17(7):1000-4. PubMed ID: 16713713
    [Abstract] [Full Text] [Related]

  • 20. Complexes of thiomandelate and captopril mercaptocarboxylate inhibitors to metallo-beta-lactamase by polarizable molecular mechanics. Validation on model binding sites by quantum chemistry.
    Antony J, Piquemal JP, Gresh N.
    J Comput Chem; 2005 Aug 21; 26(11):1131-47. PubMed ID: 15937993
    [Abstract] [Full Text] [Related]

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