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213 related items for PubMed ID: 18207204
1. SV2A protein is a broad-spectrum anticonvulsant target: functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy. Kaminski RM, Matagne A, Leclercq K, Gillard M, Michel P, Kenda B, Talaga P, Klitgaard H. Neuropharmacology; 2008 Mar; 54(4):715-20. PubMed ID: 18207204 [Abstract] [Full Text] [Related]
3. Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures. Upton N, Blackburn TP, Campbell CA, Cooper D, Evans ML, Herdon HJ, King PD, Ray AM, Stean TO, Chan WN, Evans JM, Thompson M. Br J Pharmacol; 1997 Aug; 121(8):1679-86. PubMed ID: 9283703 [Abstract] [Full Text] [Related]
4. Profile of the new pyrrolidone derivative seletracetam (ucb 44212) in animal models of epilepsy. Matagne A, Margineanu DG, Potschka H, Löscher W, Michel P, Kenda B, Klitgaard H. Eur J Pharmacol; 2009 Jul 01; 614(1-3):30-7. PubMed ID: 19383493 [Abstract] [Full Text] [Related]
6. Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy. van Vliet EA, Aronica E, Redeker S, Boer K, Gorter JA. Epilepsia; 2009 Mar 01; 50(3):422-33. PubMed ID: 18717715 [Abstract] [Full Text] [Related]
7. Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties. Gillard M, Fuks B, Leclercq K, Matagne A. Eur J Pharmacol; 2011 Aug 16; 664(1-3):36-44. PubMed ID: 21575627 [Abstract] [Full Text] [Related]
8. mGlu1 and mGlu5 receptor antagonists lack anticonvulsant efficacy in rodent models of difficult-to-treat partial epilepsy. Löscher W, Dekundy A, Nagel J, Danysz W, Parsons CG, Potschka H. Neuropharmacology; 2006 Jun 16; 50(8):1006-15. PubMed ID: 16563443 [Abstract] [Full Text] [Related]
9. Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models. Rowley NM, White HS. Epilepsy Res; 2010 Dec 16; 92(2-3):163-9. PubMed ID: 20951004 [Abstract] [Full Text] [Related]
12. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B. Proc Natl Acad Sci U S A; 2004 Jun 29; 101(26):9861-6. PubMed ID: 15210974 [Abstract] [Full Text] [Related]
13. Visualization of SV2A conformations in situ by the use of Protein Tomography. Lynch BA, Matagne A, Brännström A, von Euler A, Jansson M, Hauzenberger E, Söderhäll JA. Biochem Biophys Res Commun; 2008 Oct 31; 375(4):491-5. PubMed ID: 18692481 [Abstract] [Full Text] [Related]
14. Preferential increase in the hippocampal synaptic vesicle protein 2A (SV2A) by pentylenetetrazole kindling. Ohno Y, Ishihara S, Terada R, Kikuta M, Sofue N, Kawai Y, Serikawa T, Sasa M. Biochem Biophys Res Commun; 2009 Dec 18; 390(3):415-20. PubMed ID: 19751703 [Abstract] [Full Text] [Related]
15. Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy. Stöhr T, Kupferberg HJ, Stables JP, Choi D, Harris RH, Kohn H, Walton N, White HS. Epilepsy Res; 2007 May 18; 74(2-3):147-54. PubMed ID: 17433624 [Abstract] [Full Text] [Related]
19. Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, Kaminski RM, Gillard M, Klitgaard H. ; 2012 May 18. PubMed ID: 22787627 [Abstract] [Full Text] [Related]
20. Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam. Kaminski RM, Matagne A, Patsalos PN, Klitgaard H. Epilepsia; 2009 Mar 18; 50(3):387-97. PubMed ID: 18627416 [Abstract] [Full Text] [Related] Page: [Next] [New Search]