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Journal Abstract Search
239 related items for PubMed ID: 18227432
1. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10. Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I. Protein Sci; 2008 Feb; 17(2):261-70. PubMed ID: 18227432 [Abstract] [Full Text] [Related]
2. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,). Li Y, Li H, Smith-Gill SJ, Mariuzza RA. Biochemistry; 2000 May 30; 39(21):6296-309. PubMed ID: 10828942 [Abstract] [Full Text] [Related]
3. The role of hydrogen bonding via interfacial water molecules in antigen-antibody complexation. The HyHEL-10-HEL interaction. Yokota A, Tsumoto K, Shiroishi M, Kondo H, Kumagai I. J Biol Chem; 2003 Feb 14; 278(7):5410-8. PubMed ID: 12444085 [Abstract] [Full Text] [Related]
8. Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces. Kondo H, Shiroishi M, Matsushima M, Tsumoto K, Kumagai I. J Biol Chem; 1999 Sep 24; 274(39):27623-31. PubMed ID: 10488102 [Abstract] [Full Text] [Related]
9. Novel selection method for engineered antibodies using the mechanism of Fv fragment stabilization in the presence of antigen. Tsumoto K, Nishimiya Y, Kasai N, Ueda H, Nagamune T, Ogasahara K, Yutani K, Tokuhisa K, Matsushima M, Kumagai I. Protein Eng; 1997 Nov 24; 10(11):1311-8. PubMed ID: 9514120 [Abstract] [Full Text] [Related]
10. Thermodynamic consequences of grafting enhanced affinity toward the mutated antigen onto an antibody. The case of anti-lysozyme antibody, HyHEL-10. Nishimiya Y, Tsumoto K, Shiroishi M, Yutani K, Kumagai I. J Biol Chem; 2000 Apr 28; 275(17):12813-20. PubMed ID: 10777579 [Abstract] [Full Text] [Related]
11. Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL. Shiroishi M, Tsumoto K, Tanaka Y, Yokota A, Nakanishi T, Kondo H, Kumagai I. J Biol Chem; 2007 Mar 02; 282(9):6783-91. PubMed ID: 17166830 [Abstract] [Full Text] [Related]
12. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen. Li Y, Urrutia M, Smith-Gill SJ, Mariuzza RA. Biochemistry; 2003 Jan 14; 42(1):11-22. PubMed ID: 12515535 [Abstract] [Full Text] [Related]
13. Association of the anti-hen egg lysozyme antibody HyHEL-5 with avian species variant and mutant lysozymes. Shick KA, Xavier KA, Rajpal A, Smith-Gill SJ, Willson RC. Biochim Biophys Acta; 1997 Jul 18; 1340(2):205-14. PubMed ID: 9252107 [Abstract] [Full Text] [Related]
14. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting. Villani ME, Morea V, Consalvi V, Chiaraluce R, Desiderio A, Benvenuto E, Donini M. Mol Immunol; 2008 May 18; 45(9):2474-85. PubMed ID: 18313757 [Abstract] [Full Text] [Related]
15. Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. Shiroishi M, Yokota A, Tsumoto K, Kondo H, Nishimiya Y, Horii K, Matsushima M, Ogasahara K, Yutani K, Kumagai I. J Biol Chem; 2001 Jun 22; 276(25):23042-50. PubMed ID: 11297547 [Abstract] [Full Text] [Related]
16. Salt links dominate affinity of antibody HyHEL-5 for lysozyme through enthalpic contributions. Wibbenmeyer JA, Schuck P, Smith-Gill SJ, Willson RC. J Biol Chem; 1999 Sep 17; 274(38):26838-42. PubMed ID: 10480891 [Abstract] [Full Text] [Related]
17. Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme. Fields BA, Goldbaum FA, Dall'Acqua W, Malchiodi EL, Cauerhff A, Schwarz FP, Ysern X, Poljak RJ, Mariuzza RA. Biochemistry; 1996 Dec 03; 35(48):15494-503. PubMed ID: 8952503 [Abstract] [Full Text] [Related]
18. Role of salt bridge formation in antigen-antibody interaction. Entropic contribution to the complex between hen egg white lysozyme and its monoclonal antibody HyHEL10. Tsumoto K, Ogasahara K, Ueda Y, Watanabe K, Yutani K, Kumagai I. J Biol Chem; 1996 Dec 20; 271(51):32612-6. PubMed ID: 8955089 [Abstract] [Full Text] [Related]
19. Role of Tyr residues in the contact region of anti-lysozyme monoclonal antibody HyHEL10 for antigen binding. Tsumoto K, Ogasahara K, Ueda Y, Watanabe K, Yutani K, Kumagai I. J Biol Chem; 1995 Aug 04; 270(31):18551-7. PubMed ID: 7629185 [Abstract] [Full Text] [Related]
20. Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528. Makabe K, Nakanishi T, Tsumoto K, Tanaka Y, Kondo H, Umetsu M, Sone Y, Asano R, Kumagai I. J Biol Chem; 2008 Jan 11; 283(2):1156-66. PubMed ID: 17947238 [Abstract] [Full Text] [Related] Page: [Next] [New Search]