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Journal Abstract Search

318 related items for PubMed ID: 18238857

  • 1. Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine.
    Wen B, Ma L, Rodrigues AD, Zhu M.
    Drug Metab Dispos; 2008 May; 36(5):841-50. PubMed ID: 18238857
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  • 3. Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4.
    Kalgutkar AS, Henne KR, Lame ME, Vaz AD, Collin C, Soglia JR, Zhao SX, Hop CE.
    Chem Biol Interact; 2005 Jun 30; 155(1-2):10-20. PubMed ID: 15978881
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  • 6. Metabolism and bioactivation of 3-methylindole by human liver microsomes.
    Yan Z, Easterwood LM, Maher N, Torres R, Huebert N, Yost GS.
    Chem Res Toxicol; 2007 Jan 30; 20(1):140-8. PubMed ID: 17226936
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  • 7. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.
    Chem Res Toxicol; 2007 Nov 30; 20(11):1649-57. PubMed ID: 17907785
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  • 15. Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug.
    Bauman JN, Frederick KS, Sawant A, Walsky RL, Cox LM, Obach RS, Kalgutkar AS.
    Drug Metab Dispos; 2008 Jun 30; 36(6):1016-29. PubMed ID: 18332080
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