These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

362 related items for PubMed ID: 18240300

  • 1. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury.
    Nadler Y, Alexandrovich A, Grigoriadis N, Hartmann T, Rao KS, Shohami E, Stein R.
    Glia; 2008 Apr; 56(5):552-67. PubMed ID: 18240300
    [Abstract] [Full Text] [Related]

  • 2. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Brijbassi S, Amtul Z, Newbigging S, Westaway D, St George-Hyslop P, Rozmahel RF.
    Neurobiol Dis; 2007 Feb; 25(2):291-6. PubMed ID: 17071095
    [Abstract] [Full Text] [Related]

  • 3. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease.
    Damjanac M, Rioux Bilan A, Barrier L, Pontcharraud R, Anne C, Hugon J, Page G.
    Brain Res; 2007 Jan 12; 1128(1):40-9. PubMed ID: 17125750
    [Abstract] [Full Text] [Related]

  • 4. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
    Laudon H, Winblad B, Näslund J.
    Physiol Behav; 2007 Sep 10; 92(1-2):115-20. PubMed ID: 17588625
    [Abstract] [Full Text] [Related]

  • 5. Minor contribution of presenilin 2 for γ-secretase activity in mouse embryonic fibroblasts and adult mouse brain.
    Frånberg J, Svensson AI, Winblad B, Karlström H, Frykman S.
    Biochem Biophys Res Commun; 2011 Jan 07; 404(1):564-8. PubMed ID: 21146496
    [Abstract] [Full Text] [Related]

  • 6. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J, Ayral E, Hernandez JF, Martinez J, Checler F.
    J Neurochem; 2009 Jul 07; 110(1):275-83. PubMed ID: 19457123
    [Abstract] [Full Text] [Related]

  • 7. Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain.
    Siman R, Salidas S.
    Neuroscience; 2004 Jul 07; 129(3):615-28. PubMed ID: 15541883
    [Abstract] [Full Text] [Related]

  • 8. Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and gamma-secretase activity.
    Brunkan AL, Martinez M, Wang J, Walker ES, Beher D, Shearman MS, Goate AM.
    J Neurochem; 2005 Sep 07; 94(5):1315-28. PubMed ID: 16001967
    [Abstract] [Full Text] [Related]

  • 9. The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity.
    Kaether C, Capell A, Edbauer D, Winkler E, Novak B, Steiner H, Haass C.
    EMBO J; 2004 Dec 08; 23(24):4738-48. PubMed ID: 15549135
    [Abstract] [Full Text] [Related]

  • 10. Temporal-spatial expression of presenilin 1 and the production of amyloid-beta after acute spinal cord injury in adult rat.
    Kobayashi S, Sasaki T, Katayama T, Hasegawa T, Nagano A, Sato K.
    Neurochem Int; 2010 Feb 08; 56(3):387-93. PubMed ID: 19932144
    [Abstract] [Full Text] [Related]

  • 11. Conserved residues in juxtamembrane region of the extracellular domain of nicastrin are essential for gamma-secretase complex formation.
    Walker ES, Martinez M, Wang J, Goate A.
    J Neurochem; 2006 Jul 08; 98(1):300-9. PubMed ID: 16805816
    [Abstract] [Full Text] [Related]

  • 12. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB, Franko M, Banks WA, Kasinadhuni P, Farr SA, Vyas K, Choudhuri V, Morley JE.
    J Exp Biol; 2009 Feb 08; 212(Pt 4):494-8. PubMed ID: 19181896
    [Abstract] [Full Text] [Related]

  • 13. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K, Tomioka M, Kremmer E, Haass C, Steiner H.
    Neurobiol Dis; 2007 Jul 08; 27(1):102-7. PubMed ID: 17560791
    [Abstract] [Full Text] [Related]

  • 14. Neprilysin activity and expression are controlled by nicastrin.
    Pardossi-Piquard R, Dunys J, Yu G, St George-Hyslop P, Alves da Costa C, Checler F.
    J Neurochem; 2006 May 08; 97(4):1052-6. PubMed ID: 16606360
    [Abstract] [Full Text] [Related]

  • 15. PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity.
    Aoyagi N, Uemura K, Kuzuya A, Kihara T, Kawamata J, Shimohama S, Kinoshita A, Takahashi R.
    Biochem Biophys Res Commun; 2010 Jan 08; 391(2):1240-5. PubMed ID: 20006583
    [Abstract] [Full Text] [Related]

  • 16. Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
    Ilaya NT, Evin G, Masters CL, Culvenor JG.
    J Neurochem; 2004 Oct 08; 91(1):230-7. PubMed ID: 15379903
    [Abstract] [Full Text] [Related]

  • 17. Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
    Evin G, Canterford LD, Hoke DE, Sharples RA, Culvenor JG, Masters CL.
    Biochemistry; 2005 Mar 22; 44(11):4332-41. PubMed ID: 15766262
    [Abstract] [Full Text] [Related]

  • 18. Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia.
    Stalder AK, Pagenstecher A, Yu NC, Kincaid C, Chiang CS, Hobbs MV, Bloom FE, Campbell IL.
    J Immunol; 1997 Aug 01; 159(3):1344-51. PubMed ID: 9233631
    [Abstract] [Full Text] [Related]

  • 19. Reconstitution of gamma-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of gamma-secretase complex.
    Shiraishi H, Marutani T, Wang HQ, Maeda Y, Kurono Y, Takashima A, Araki W, Nishimura M, Yanagisawa K, Komano H.
    Genes Cells; 2006 Jan 01; 11(1):83-93. PubMed ID: 16371134
    [Abstract] [Full Text] [Related]

  • 20. CD147, a gamma-secretase associated protein is upregulated in Alzheimer's disease brain and its cellular trafficking is affected by presenilin-2.
    Nahalkova J, Volkmann I, Aoki M, Winblad B, Bogdanovic N, Tjernberg LO, Behbahani H.
    Neurochem Int; 2010 Jan 01; 56(1):67-76. PubMed ID: 19751784
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 19.