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Journal Abstract Search


299 related items for PubMed ID: 18252896

  • 1. Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.
    Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.
    Diabetes; 2008 May; 57(5):1205-15. PubMed ID: 18252896
    [Abstract] [Full Text] [Related]

  • 2. Exendin-4 inhibits interleukin-1beta-induced iNOS expression at the protein level, but not at the transcriptional and posttranscriptional levels, in RINm5F beta-cells.
    Kang JH, Chang SY, Jang HJ, Kim DB, Ryu GR, Ko SH, Jeong IK, Jo YH, Kim MJ.
    J Endocrinol; 2009 Jul; 202(1):65-75. PubMed ID: 19398497
    [Abstract] [Full Text] [Related]

  • 3. Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
    Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.
    Diabetes; 2008 Apr; 57(4):967-79. PubMed ID: 18162507
    [Abstract] [Full Text] [Related]

  • 4. Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways.
    Li XL, Xu G, Chen T, Wong YS, Zhao HL, Fan RR, Gu XM, Tong PC, Chan JC.
    Int J Biochem Cell Biol; 2009 Jul; 41(7):1526-35. PubMed ID: 19166964
    [Abstract] [Full Text] [Related]

  • 5. Exendin-4 induction of Egr-1 expression in INS-1 beta-cells: interaction of SRF, not YY1, with SRE site of rat Egr-1 promoter.
    Kim MJ, Kang JH, Chang SY, Jang HJ, Ryu GR, Ko SH, Jeong IK, Kim MS, Jo YH.
    J Cell Biochem; 2008 Aug 15; 104(6):2261-71. PubMed ID: 18446785
    [Abstract] [Full Text] [Related]

  • 6. Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4.
    Xiang JN, Chen DL, Yang LY.
    Biochem Biophys Res Commun; 2012 May 18; 421(4):701-6. PubMed ID: 22542939
    [Abstract] [Full Text] [Related]

  • 7. Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction.
    Eckhoff DE, Smyth CA, Eckstein C, Bilbao G, Young CJ, Thompson JA, Contreras JL.
    Surgery; 2003 Aug 18; 134(2):169-79. PubMed ID: 12947315
    [Abstract] [Full Text] [Related]

  • 8. Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1.
    Blandino-Rosano M, Perez-Arana G, Mellado-Gil JM, Segundo C, Aguilar-Diosdado M.
    J Mol Endocrinol; 2008 Jul 18; 41(1):35-44. PubMed ID: 18487229
    [Abstract] [Full Text] [Related]

  • 9. Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic beta-cells.
    Shao W, Yu Z, Fantus IG, Jin T.
    Cell Signal; 2010 Aug 18; 22(8):1240-6. PubMed ID: 20385228
    [Abstract] [Full Text] [Related]

  • 10. Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway.
    Díaz-Delfín J, Morales M, Caelles C.
    Diabetes; 2007 Jul 18; 56(7):1865-71. PubMed ID: 17416798
    [Abstract] [Full Text] [Related]

  • 11. JNK-AP-1 pathway involved in interleukin-1beta-induced calcitonin gene-related peptide secretion in human type II alveolar epithelial cells.
    Li W, Zheng S, Tang C, Zhu Y, Wang X.
    Peptides; 2007 Jun 18; 28(6):1252-9. PubMed ID: 17481780
    [Abstract] [Full Text] [Related]

  • 12. Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.
    Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I.
    J Endocrinol; 2007 Apr 18; 193(1):65-74. PubMed ID: 17400804
    [Abstract] [Full Text] [Related]

  • 13. Exendin-4 regulates GLUT2 expression via the CaMKK/CaMKIV pathway in a pancreatic β-cell line.
    Chen K, Yu X, Murao K, Imachi H, Li J, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.
    Metabolism; 2011 Apr 18; 60(4):579-85. PubMed ID: 20598720
    [Abstract] [Full Text] [Related]

  • 14. Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells.
    Natalicchio A, De Stefano F, Orlando MR, Melchiorre M, Leonardini A, Cignarelli A, Labarbuta R, Marchetti P, Perrini S, Laviola L, Giorgino F.
    Endocrinology; 2010 May 18; 151(5):2019-29. PubMed ID: 20219981
    [Abstract] [Full Text] [Related]

  • 15. Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis.
    Fan R, Li X, Gu X, Chan JC, Xu G.
    Diabetes Obes Metab; 2010 Sep 18; 12(9):815-24. PubMed ID: 20649634
    [Abstract] [Full Text] [Related]

  • 16. Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
    Gurzov EN, Ortis F, Cunha DA, Gosset G, Li M, Cardozo AK, Eizirik DL.
    Cell Death Differ; 2009 Nov 18; 16(11):1539-50. PubMed ID: 19629134
    [Abstract] [Full Text] [Related]

  • 17. Helioxanthin inhibits interleukin-1 beta-induced MIP-1 beta production by reduction of c-jun expression and binding of the c-jun/CREB1 complex to the AP-1/CRE site of the MIP-1 beta promoter in Huh7 cells.
    Tseng PC, Hsu HC, Janmanchi D, Lin CH, Kuo YH, Chou CK, Yeh SF.
    Biochem Pharmacol; 2008 Oct 30; 76(9):1121-33. PubMed ID: 18789903
    [Abstract] [Full Text] [Related]

  • 18. Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.
    Klinger S, Poussin C, Debril MB, Dolci W, Halban PA, Thorens B.
    Diabetes; 2008 Mar 30; 57(3):584-93. PubMed ID: 18025410
    [Abstract] [Full Text] [Related]

  • 19. Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells.
    Romero L, Andrews K, Ng L, O'Rourke K, Maslen A, Kirby G.
    Biochem J; 2006 Nov 15; 400(1):135-41. PubMed ID: 16836488
    [Abstract] [Full Text] [Related]

  • 20. Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues.
    Tews D, Werner U, Eckel J.
    Horm Metab Res; 2008 Mar 15; 40(3):172-80. PubMed ID: 18348079
    [Abstract] [Full Text] [Related]


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