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Journal Abstract Search

226 related items for PubMed ID: 18253123

  • 1. 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.
    Wang W, Wang H, Rayburn ER, Zhao Y, Hill DL, Zhang R.
    Br J Cancer; 2008 Feb 26; 98(4):792-802. PubMed ID: 18253123
    [Abstract] [Full Text] [Related]

  • 2. Isolation, structural determination, and evaluation of the biological activity of 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol [20(S)-25-OCH3-PPD], a novel natural product from Panax notoginseng.
    Zhao Y, Wang W, Han L, Rayburn ER, Hill DL, Wang H, Zhang R.
    Med Chem; 2007 Jan 26; 3(1):51-60. PubMed ID: 17266624
    [Abstract] [Full Text] [Related]

  • 3. Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides.
    Wang W, Rayburn ER, Hao M, Zhao Y, Hill DL, Zhang R, Wang H.
    Prostate; 2008 Jun 01; 68(8):809-19. PubMed ID: 18324646
    [Abstract] [Full Text] [Related]

  • 4. Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2.
    Wang W, Zhang X, Qin JJ, Voruganti S, Nag SA, Wang MH, Wang H, Zhang R.
    PLoS One; 2012 Jun 01; 7(7):e41586. PubMed ID: 22911819
    [Abstract] [Full Text] [Related]

  • 5. Anti-lung cancer effects of novel ginsenoside 25-OCH(3)-PPD.
    Wang W, Rayburn ER, Hang J, Zhao Y, Wang H, Zhang R.
    Lung Cancer; 2009 Sep 01; 65(3):306-11. PubMed ID: 19131140
    [Abstract] [Full Text] [Related]

  • 6. 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells.
    Ai HH, Zhou ZL, Sun LG, Yang MT, Li W, Yu CL, Song ZB, Huang YX, Wu Y, Liu L, Yang XG, Zhao YQ, Bao YL, Li YX.
    Apoptosis; 2017 Nov 01; 22(11):1404-1418. PubMed ID: 28864870
    [Abstract] [Full Text] [Related]

  • 7. 20(S)-25-methoxyl-dammarane-3β,12β,20-triol attenuates endoplasmic reticulum stress via ERK/MAPK signaling pathway.
    Qin H, Li W, Sun Y, Bao Y, Sun L, Song Z, Zheng L, Zhao Y, Li Y.
    Eur J Pharmacol; 2018 Oct 05; 836():75-82. PubMed ID: 30096296
    [Abstract] [Full Text] [Related]

  • 8. Novel ginsenosides 25-OH-PPD and 25-OCH3-PPD as experimental therapy for pancreatic cancer: anticancer activity and mechanisms of action.
    Wang W, Rayburn ER, Zhao Y, Wang H, Zhang R.
    Cancer Lett; 2009 Jun 18; 278(2):241-248. PubMed ID: 19203832
    [Abstract] [Full Text] [Related]

  • 9. New perspective on the metabolism of AD-1 in vivo: Characterization of a series of dammarane-type derivatives with novel metabolic sites and anticancer mechanisms of active oleanane-type metabolites.
    Ding M, Wang X, Zhang Y, Yuan W, Zhang H, Xu L, Wang Z, Lu J, Li W, Zhao Y.
    Bioorg Chem; 2019 Jul 18; 88():102961. PubMed ID: 31075741
    [Abstract] [Full Text] [Related]

  • 10. Stereoselective pharmacokinetics of 25-methoxyl-dammarane-3β,12β,20-triol and its active demethyl-metabolite epimers in rats after oral and intravenous administration.
    Shao N, Jiang H, Wang X, Yuan B, Jin Y, Song M, Zhao Y, Xu H.
    Fitoterapia; 2017 Jan 18; 116():139-145. PubMed ID: 27940119
    [Abstract] [Full Text] [Related]

  • 11. Natural Product Ginsenoside 20(S)-25-Methoxyl-Dammarane-3β, 12β, 20-Triol in Cancer Treatment: A Review of the Pharmacological Mechanisms and Pharmacokinetics.
    Kim D, Park M, Haleem I, Lee Y, Koo J, Na YC, Song G, Lee J.
    Front Pharmacol; 2020 Jan 18; 11():521. PubMed ID: 32425780
    [Abstract] [Full Text] [Related]

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  • 15. In vitro metabolism of 20(R)-25-methoxyl-dammarane-3, 12, 20-triol from Panax notoginseng in human, monkey, dog, rat, and mouse liver microsomes.
    Zhang X, Zhang J, Li W, Liu L, Sun B, Guo Z, Shi C, Zhao Y.
    PLoS One; 2014 Jan 18; 9(4):e94962. PubMed ID: 24736630
    [Abstract] [Full Text] [Related]

  • 16. 25-methoxyl-dammarane-3β, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation through downregulation of testes-specific protease 50 (TSP50) expression.
    Wang D, Zhao Y, Wang Y, Rong Y, Qin H, Bao Y, Song Z, Yu C, Sun L, Li Y.
    Tumour Biol; 2016 Sep 18; 37(9):11805-11813. PubMed ID: 27039397
    [Abstract] [Full Text] [Related]

  • 17. In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng.
    Wang W, Zhao Y, Rayburn ER, Hill DL, Wang H, Zhang R.
    Cancer Chemother Pharmacol; 2007 Apr 18; 59(5):589-601. PubMed ID: 16924497
    [Abstract] [Full Text] [Related]

  • 18. Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways.
    Gao JL, Lv GY, He BC, Zhang BQ, Zhang H, Wang N, Wang CZ, Du W, Yuan CS, He TC.
    Oncol Rep; 2013 Jul 18; 30(1):292-8. PubMed ID: 23633038
    [Abstract] [Full Text] [Related]

  • 19. Novel dammarane-type sapogenins from Panax ginseng berry and their biological activities.
    Zhao JM, Li N, Zhang H, Wu CF, Piao HR, Zhao YQ.
    Bioorg Med Chem Lett; 2011 Feb 01; 21(3):1027-31. PubMed ID: 21216145
    [Abstract] [Full Text] [Related]

  • 20. Pharmacokinetics of 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol and its active metabolite after oral and intravenous administration in rat.
    Zhang X, Xu J, Zhang D, Gu J, Zhao Y.
    Xenobiotica; 2009 Jun 01; 39(6):457-64. PubMed ID: 19480551
    [Abstract] [Full Text] [Related]

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