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644 related items for PubMed ID: 18253720

  • 1. Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats.
    Nishimura J, Dewa Y, Okamura T, Muguruma M, Jin M, Saegusa Y, Umemura T, Mitsumori K.
    Arch Toxicol; 2008 Sep; 82(9):641-54. PubMed ID: 18253720
    [Abstract] [Full Text] [Related]

  • 2. Effect of fenofibrate on oxidative DNA damage and on gene expression related to cell proliferation and apoptosis in rats.
    Nishimura J, Dewa Y, Muguruma M, Kuroiwa Y, Yasuno H, Shima T, Jin M, Takahashi M, Umemura T, Mitsumori K.
    Toxicol Sci; 2007 May; 97(1):44-54. PubMed ID: 17264098
    [Abstract] [Full Text] [Related]

  • 3. beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.
    Dewa Y, Nishimura J, Muguruma M, Jin M, Saegusa Y, Okamura T, Tasaki M, Umemura T, Mitsumori K.
    Toxicology; 2008 Feb 28; 244(2-3):179-89. PubMed ID: 18164116
    [Abstract] [Full Text] [Related]

  • 4. Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine.
    Shimamoto K, Dewa Y, Ishii Y, Kemmochi S, Taniai E, Hayashi H, Imaoka M, Morita R, Kuwata K, Suzuki K, Shibutani M, Mitsumori K.
    Toxicology; 2011 May 10; 283(2-3):109-17. PubMed ID: 21396975
    [Abstract] [Full Text] [Related]

  • 5. Possible involvement of oxidative stress in piperonyl butoxide induced hepatocarcinogenesis in rats.
    Muguruma M, Unami A, Kanki M, Kuroiwa Y, Nishimura J, Dewa Y, Umemura T, Oishi Y, Mitsumori K.
    Toxicology; 2007 Jul 01; 236(1-2):61-75. PubMed ID: 17498859
    [Abstract] [Full Text] [Related]

  • 6. Role of Nrf2 and oxidative stress on fenofibrate-induced hepatocarcinogenesis in rats.
    Nishimura J, Dewa Y, Okamura T, Jin M, Saegusa Y, Kawai M, Umemura T, Shibutani M, Mitsumori K.
    Toxicol Sci; 2008 Dec 01; 106(2):339-49. PubMed ID: 18775883
    [Abstract] [Full Text] [Related]

  • 7. Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression.
    Kinoshita A, Wanibuchi H, Morimura K, Wei M, Shen J, Imaoka S, Funae Y, Fukushima S.
    Carcinogenesis; 2003 Aug 01; 24(8):1389-99. PubMed ID: 12807726
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of in vivo genotoxic potential of fenofibrate in rats subjected to two-week repeated oral administration.
    Tawfeeq MM, Suzuki T, Shimamoto K, Hayashi H, Shibutani M, Mitsumori K.
    Arch Toxicol; 2011 Aug 01; 85(8):1003-11. PubMed ID: 21127841
    [Abstract] [Full Text] [Related]

  • 9. Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats.
    Dewa Y, Nishimura J, Muguruma M, Jin M, Kawai M, Saegusa Y, Okamura T, Umemura T, Mitsumori K.
    Arch Toxicol; 2009 May 01; 83(5):503-11. PubMed ID: 18754104
    [Abstract] [Full Text] [Related]

  • 10. Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.
    Shimamoto K, Dewa Y, Kemmochi S, Taniai E, Hayashi H, Imaoka M, Shibutani M, Mitsumori K.
    Arch Toxicol; 2011 Sep 01; 85(9):1159-66. PubMed ID: 21203749
    [Abstract] [Full Text] [Related]

  • 11. Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice.
    Moto M, Okamura M, Muguruma M, Ito T, Jin M, Kashida Y, Mitsumori K.
    Toxicol Pathol; 2006 Sep 01; 34(6):744-51. PubMed ID: 17162532
    [Abstract] [Full Text] [Related]

  • 12. Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats.
    Muguruma M, Kawai M, Dewa Y, Nishimura J, Saegusa Y, Yasuno H, Jin M, Matsumoto S, Takabatake M, Arai K, Mitsumori K.
    Arch Toxicol; 2009 Feb 01; 83(2):183-93. PubMed ID: 18648771
    [Abstract] [Full Text] [Related]

  • 13. Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
    Hayashi M, Tamura T, Kuroda J, Ohnota H, Shibata N, Akahane M, Kashida Y, Mitsumori K.
    Toxicol Sci; 2005 Mar 01; 84(1):22-8. PubMed ID: 15564315
    [Abstract] [Full Text] [Related]

  • 14. A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay.
    Ou YC, Conolly RB, Thomas RS, Xu Y, Andersen ME, Chubb LS, Pitot HC, Yang RS.
    Cancer Res; 2001 Mar 01; 61(5):1879-89. PubMed ID: 11280742
    [Abstract] [Full Text] [Related]

  • 15. Mechanistic study on liver tumor promoting effects of flutamide in rats.
    Tawfeeq MM, Hayashi H, Shimamoto K, Suzuki K, Shibutani M, Inokuma H, Mitsumori K.
    Arch Toxicol; 2012 Mar 01; 86(3):497-507. PubMed ID: 22076107
    [Abstract] [Full Text] [Related]

  • 16. Oxidative stress in carcinogenesis. Correlation between lipid peroxidation and induction of preneoplastic lesions in rat hepatocarcinogenesis.
    Sánchez-Pérez Y, Carrasco-Legleu C, García-Cuellar C, Pérez-Carreón J, Hernández-García S, Salcido-Neyoy M, Alemán-Lazarini L, Villa-Treviño S.
    Cancer Lett; 2005 Jan 10; 217(1):25-32. PubMed ID: 15596293
    [Abstract] [Full Text] [Related]

  • 17. Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
    Hayashi M, Ohnota H, Tamura T, Kuroda J, Shibata N, Akahane M, Moriwaki H, Machida N, Mitsumori K.
    Arch Toxicol; 2004 Aug 10; 78(8):460-6. PubMed ID: 15034639
    [Abstract] [Full Text] [Related]

  • 18. Induction of liver preneoplastic foci in F344 rats subjected to 28-day oral administration of diheptyl phthalate and its in vivo genotoxic potential.
    Jin M, Dewa Y, Kawai M, Nishimura J, Saegusa Y, Kemmochi S, Harada T, Shibutani M, Mitsumori K.
    Toxicology; 2009 Oct 01; 264(1-2):16-25. PubMed ID: 19643158
    [Abstract] [Full Text] [Related]

  • 19. Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.
    Kawai M, Saegusa Y, Dewa Y, Nishimura J, Kemmochi S, Harada T, Ishii Y, Umemura T, Shibutani M, Mitsumori K.
    Arch Toxicol; 2010 Feb 01; 84(2):155-64. PubMed ID: 20101389
    [Abstract] [Full Text] [Related]

  • 20. Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model.
    Dewa Y, Nishimura J, Jin M, Kawai M, Saegusa Y, Kenmochi S, Shimamoto K, Harada T, Shibutani M, Mitsumori K.
    Arch Toxicol; 2011 Feb 01; 85(2):155-62. PubMed ID: 20502879
    [Abstract] [Full Text] [Related]

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