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220 related items for PubMed ID: 1825652

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  • 3. Rate and extent of interconversion of tetrahydrofolate cofactors to dihydrofolate after cessation of dihydrofolate reductase activity in stationary versus log phase L1210 leukemia cells.
    Trent DF, Seither RL, Goldman ID.
    J Biol Chem; 1991 Mar 25; 266(9):5445-9. PubMed ID: 1825999
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  • 5. Compartmentation of intracellular folates. Failure to interconvert tetrahydrofolate cofactors to dihydrofolate in mitochondria of L1210 leukemia cells treated with trimetrexate.
    Trent DF, Seither RL, Goldman ID.
    Biochem Pharmacol; 1991 Aug 08; 42(5):1015-9. PubMed ID: 1831361
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  • 6. Evidence for a localized conversion of endogenous tetrahydrofolate cofactors to dihydrofolate as an important element in antifolate action in murine leukemia cells.
    Matherly LH, Muench SP.
    Biochem Pharmacol; 1990 Jun 15; 39(12):2005-14. PubMed ID: 2141258
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  • 7. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 15; 46(2):588-93. PubMed ID: 2416428
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  • 8. The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase.
    Galivan J, Rhee MS, Johnson TB, Dilwith R, Nair MG, Bunni M, Priest DG.
    J Biol Chem; 1989 Jun 25; 264(18):10685-92. PubMed ID: 2525127
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  • 9. Predictions of a network thermodynamics computer model relating to the mechanism of methotrexate rescue by 5-formyltetrahydrofolate and to the importance of inhibition of thymidylate synthase by methotrexate-polyglutamates.
    White JC.
    Adv Exp Med Biol; 1983 Jun 25; 163():305-26. PubMed ID: 6193692
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  • 10. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL, McQueen CA, DeAngelis LM, Bertino JR.
    Cancer Res; 1976 Jul 25; 36(7 PT 1):2442-9. PubMed ID: 1277151
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  • 11. Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
    Jackson RC, Fry DW, Boritzki TJ, Besserer JA, Leopold WR, Sloan BJ, Elslager EF.
    Adv Enzyme Regul; 1984 Jul 25; 22():187-206. PubMed ID: 6236675
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  • 12. Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1989 Mar 01; 38(5):815-22. PubMed ID: 2467676
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  • 13. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
    Galivan J, Nimec Z, Rhee M, Boschelli D, Oronsky AL, Kerwar SS.
    Cancer Res; 1988 May 01; 48(9):2421-5. PubMed ID: 2965613
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  • 14. Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
    Galivan J, Nimec Z, Rhee M.
    Cancer Res; 1987 Oct 15; 47(20):5256-60. PubMed ID: 2958130
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  • 15. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr 15; 45(4):783-91. PubMed ID: 7514264
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  • 18. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, Shackelford KA, Mendelsohn LG, Soose DJ, Patel VF, Andis SL, Bewley JR, Rayl EA, Moroson BA, Beardsley GP, Kohler W, Ratnam M, Schultz RM.
    Cancer Res; 1997 Mar 15; 57(6):1116-23. PubMed ID: 9067281
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  • 19. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells.
    Rhee MS, Balinska M, Bunni M, Priest DG, Maley GF, Maley F, Galivan J.
    Cancer Res; 1990 Jul 01; 50(13):3979-84. PubMed ID: 2162250
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  • 20. Depletion of 5,10-methylenetetrahydrofolate and 10-formyltetrahydrofolate by methotrexate in cultured hepatoma cells.
    Rhee MS, Coward JK, Galivan J.
    Mol Pharmacol; 1992 Nov 01; 42(5):909-16. PubMed ID: 1435754
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