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220 related items for PubMed ID: 1825652

  • 21. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate.
    Assaraf YG, Molina A, Schimke RT.
    J Biol Chem; 1989 Nov 05; 264(31):18326-34. PubMed ID: 2572592
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  • 22. Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase.
    Cheng YC, Dutschman GE, Starnes MC, Fisher MH, Nanavathi NT, Nair MG.
    Cancer Res; 1985 Feb 05; 45(2):598-600. PubMed ID: 3917852
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  • 23. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.
    Sharma RC, Assaraf YG, Schimke RT.
    Cancer Res; 1991 Jun 01; 51(11):2949-59. PubMed ID: 1674447
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  • 24. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study.
    Jackman AL, Taylor GA, Gibson W, Kimbell R, Brown M, Calvert AH, Judson IR, Hughes LR.
    Cancer Res; 1991 Oct 15; 51(20):5579-86. PubMed ID: 1913676
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  • 25. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
    Mauritz R, Bekkenk MW, Rots MG, Pieters R, Mini E, van Zantwijk CH, Veerman AJ, Peters GJ, Jansen G.
    Clin Cancer Res; 1998 Oct 15; 4(10):2399-410. PubMed ID: 9796971
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  • 26. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.
    Bunni M, Doig MT, Donato H, Kesavan V, Priest DG.
    Cancer Res; 1988 Jun 15; 48(12):3398-404. PubMed ID: 3370638
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  • 32. Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo.
    Mauritz R, Peters GJ, Kathmann I, Teshale H, Noordhuis P, Comijn EM, Pinedo HM, Jansen G.
    Cancer Chemother Pharmacol; 2008 Nov 15; 62(6):937-48. PubMed ID: 18283461
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  • 33. Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.
    Assaraf YG, Ifergan I, Kadry WN, Pinter RY.
    J Theor Biol; 2006 Jun 21; 240(4):637-47. PubMed ID: 16352313
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  • 37. The effects on 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue.
    Matherly LH, Barlowe CK, Phillips VM, Goldman ID.
    J Biol Chem; 1987 Jan 15; 262(2):710-7. PubMed ID: 2948949
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  • 40. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
    Allegra CJ, Hoang K, Yeh GC, Drake JC, Baram J.
    J Biol Chem; 1987 Oct 05; 262(28):13520-6. PubMed ID: 2443493
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